Search Results - "Ko, Ryan B"
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Noninvasive Early Identification of Therapeutic Benefit from Immune Checkpoint Inhibition
Published in Cell (15-10-2020)“…Although treatment of non-small cell lung cancer (NSCLC) with immune checkpoint inhibitors (ICIs) can produce remarkably durable responses, most patients…”
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Real-world risk of brain metastases in stage III non-small cell lung cancer in the era of PET and MRI staging
Published in Frontiers in oncology (24-03-2023)“…The 2-year incidence of brain metastases (BrMs) in stage III non-small lung cell cancer (NSCLC) has been estimated to be around 30%. However, recent clinical…”
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3
FLASH Irradiation Results in Reduced Severe Skin Toxicity Compared to Conventional-Dose-Rate Irradiation
Published in Radiation research (01-12-2020)“…Radiation therapy, along with surgery and chemotherapy, is one of the main treatments for cancer. While radiotherapy is highly effective in the treatment of…”
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Circulating Tumor DNA Analysis to Assess Risk of Progression after Long-term Response to PD-(L)1 Blockade in NSCLC
Published in Clinical cancer research (15-06-2020)“…Treatment with PD-(L)1 blockade can produce remarkably durable responses in patients with non-small cell lung cancer (NSCLC). However, a significant fraction…”
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Circulating Tumor DNA Dynamics Predict Benefit from Consolidation Immunotherapy in Locally Advanced Non-Small Cell Lung Cancer
Published in Nature cancer (01-02-2020)“…Circulating tumor DNA (ctDNA) molecular residual disease (MRD) following curative-intent treatment strongly predicts recurrence in multiple tumor types, but…”
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Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer
Published in Radiotherapy and oncology (01-02-2024)“…•Pulmonary interstitial lymphography is feasible to identify primary nodal drainage.•Contrast was visualized in all patients; drainage frequently involved…”
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Dosimetric calibration of anatomy-specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments
Published in Medical physics (Lancaster) (27-09-2024)“…FLASH radiation therapy (RT) offers a promising avenue for the broadening of the therapeutic index. However, to leverage the full potential of FLASH in the…”
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Evaluating the Reproducibility of Mouse Anatomy under Rotation in a Custom Immobilization Device for Conformal FLASH Radiotherapy
Published in Radiation research (01-12-2020)“…The observation of an enhanced therapeutic index for FLASH radiotherapy in mice has created interest in practical laboratory-based FLASH irradiators. To date,…”
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Pulmonary Hemorrhage in Patients Treated With Thoracic Stereotactic Ablative Radiotherapy and Antiangiogenic Agents
Published in Journal of thoracic oncology (01-07-2023)“…Severe pulmonary hemorrhage can occur in patients treated with thoracic stereotactic ablative radiotherapy (SABR) and vascular endothelial growth factor…”
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Vaping-Related Clotting Phenomena Presenting As Central Retinal Vein Occlusion
Published in Curēus (Palo Alto, CA) (05-08-2022)“…Central retinal vein occlusion (CRVO) typically manifests as unilateral vision loss from thrombosis and occlusion of the central retinal vein in patients with…”
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Isolated Nodal Recurrence After Definitive Stereotactic Ablative Radiation Therapy for Non-Small Cell Lung Cancer
Published in Practical Radiation Oncology (01-01-2023)“…Stereotactic ablative radiation therapy (SABR) results in high rates of primary tumor control for early-stage non-small cell lung cancer (NSCLC). For patients…”
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Patient motion tracking for non‐isocentric and non‐coplanar treatments via fixed frame‐of‐reference 3D camera
Published in Journal of applied clinical medical physics (01-03-2020)“…Purpose As C‐arm linac radiation therapy evolves toward faster, more efficient delivery, and more conformal dosimetry, treatments with increasingly complex…”
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Abstract 5666: A noninvasive approach for early prediction of therapeutic benefit from immune checkpoint inhibition for lung cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Although treatment of non-small cell lung cancer (NSCLC) with immune checkpoint inhibitors (ICI) can produce remarkably durable responses, most…”
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Integrating genomic features for noninvasive early lung cancer detection
Published in Nature (London) (25-03-2020)“…Radiologic screening of high-risk adults reduces lung cancer-related mortality 1 – 3 . Despite this, < 5% of eligible individuals undergo such screening in the…”
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Dosimetric calibration of an anatomically specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments
Published 17-12-2023“…We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and…”
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16
Vaping-Related Clotting Phenomena Presenting As Central Retinal Vein Occlusion
Published in Cureus (01-08-2022)Get full text
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