Search Results - "Ko, Paul"

Non-antibody protein-based biosensors by Ko Ferrigno, Paul

“…Biosensors that depend on a physical or chemical measurement can be adversely affected by non-specific interactions. For example, a biosensor designed to…”
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Pharmacokinetics of levonorgestrel and etonogestrel in rat or minipig following intravenous, subcutaneous, or intradermal administration by Ko, Paul J., Milad, Mark A., Radulovic, Louis L., Gibson, Don M.

“…The objective of these studies was to determine the pharmacokinetics of levonorgestrel and etonogestrel in Sprague-Dawley rat or Göttingen minipig following…”
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The role of BCL6 in lymphomas and routes to therapy by Wagner, Simon D., Ahearne, Matthew, Ferrigno, Paul Ko

“…Summary BCL6 is a transcription factor that has essential B‐cell and T‐cell roles in normal antibody responses. It is involved in chromosomal translocations in…”
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Sensitive and selective Affimer-functionalised interdigitated electrode-based capacitive biosensor for Her4 protein tumour biomarker detection by Zhurauski, Pavel, Arya, Sunil K., Jolly, Pawan, Tiede, Christian, Tomlinson, Darren C., Ko Ferrigno, Paul, Estrela, Pedro

“…A novel Affimer-functionalised interdigitated electrode-based capacitive biosensor platform was developed for detection and estimation of Her4, a protein…”
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In silico discovery and in vitro activity of inhibitors against Mycobacterium tuberculosis 7,8-diaminopelargonic acid synthase ( Mtb BioA) by Billones, Junie B, Carrillo, Maria Constancia O, Organo, Voltaire G, Sy, Jamie Bernadette A, Clavio, Nina Abigail B, Macalino, Stephani Joy Y, Emnacen, Inno A, Lee, Alexandra P, Ko, Paul Kenny L, Concepcion, Gisela P

“…Computer-aided drug discovery and development approaches such as virtual screening, molecular docking, and in silico drug property calculations have been…”
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Student-led curricular approaches in medical education: the educational effects of a virtual fundamentals of COVID-19 course by Chiu, Megan Z, Gerena, Rolando G, Roll, Rebekah L, Baker, Joseph M, Gomez, Maritza, Brown, Cameron M, Brenner, Abigail M, Huang, Christina C, Ko, Paul Y, Bauer, Margaret E, Trujillo, Daniel J

“…As the field of education was adapting to virtual learning during the COVID-19 pandemic, a need quickly emerged for a course to prepare medical students for…”
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Increasing experimental reproducibility, from antibodies to protein arrays by Ko Ferrigno, Paul

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Randomized trial of a novel ACLS teaching tool: does it improve student performance? by Nacca, Nicholas, Holliday, Jordan, Ko, Paul Y

“…Mounting evidence suggests that high-fidelity mannequin-based (HFMBS) and computer-based simulation are useful adjunctive educational tools for advanced…”
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The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain by Evans, Sian E, Goult, Benjamin T, Fairall, Louise, Jamieson, Andrew G, Ko Ferrigno, Paul, Ford, Robert, Schwabe, John W R, Wagner, Simon D

“…BCL6 is a transcriptional repressor that is over-expressed due to chromosomal translocations, or other abnormalities, in ∼40% of diffuse large B-cell lymphoma…”
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Peptide Aptamers in Label-Free Protein Detection: 1. Characterization of the Immobilized Scaffold by Davis, Jason J, Tkac, Jan, Laurenson, Sophie, Ferrigno, Paul Ko

“…Protein microarray development is absolutely dependent upon the ability to construct interfaces capable of specific, stable, sensitive, and designable…”
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Incidental Findings on CT Scans in the Emergency Department by Thompson, Ryan J., Wojcik, Susan M., Grant, William D., Ko, Paul Y.

“…Objectives. Incidental findings on computed tomography (CT) scans are common. We sought to examine rates of findings and disclosure among discharged patients…”
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Sensitive Affimer and Antibody Based Impedimetric Label-Free Assays for C‑Reactive Protein by Johnson, Anthony, Song, Qifeng, Ko Ferrigno, Paul, Bueno, Paulo R, Davis, Jason J

“…C-reactive protein (CRP) is an acute phase protein whose levels are increased in many disorders. Levels greater than 3 μg/mL serum have hitherto been…”
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Peptide Aptamers in Label-Free Protein Detection: 2. Chemical Optimization and Detection of Distinct Protein Isoforms by Davis, Jason J, Tkac, Jan, Humphreys, Rachel, Buxton, Anthony T, Lee, Tracy A, Ko Ferrigno, Paul

“…The early detection and diagnosis of cancer lies central to successful treatment and improved patient outcome. Current techniques are limited by the nature of…”
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Highly specific label-free protein detection from lysed cells using internally referenced microcantilever sensors by Shu, Wenmiao, Laurenson, Sophie, Knowles, Tuomas P.J., Ko Ferrigno, Paul, Seshia, Ashwin A.

“…We report the investigation of label-free protein detection directly from lysed cells using microcantilever sensors. The integration of an internally…”
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Design and Validation of a Neutral Protein Scaffold for the Presentation of Peptide Aptamers by Woodman, Robbie, Yeh, Johannes T.-H., Laurenson, Sophie, Ferrigno, Paul Ko

“…Peptide aptamers are peptides constrained and presented by a scaffold protein that are used to study protein function in cells. They are able to disrupt…”
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Comparison of a Modified Longitudinal Simulation-Based Advanced Cardiovascular Life Support to a Traditional Advanced Cardiovascular Life Support Curriculum in Third-Year Medical Students by Ko, Paul Y., Scott, Jay M., Mihai, Aurel, Grant, William D.

“…Background: Simulation is an effective tool for teaching medical students in cardiac arrest management. Purpose: The purpose of this article is to compare the…”
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Comparison of the specificity and affinity of surface immobilised Affimer binders using the quartz crystal microbalance by Weckman, Nicole E, McRae, Cassey, Ko Ferrigno, Paul, Seshia, Ashwin A

“…To enable multiplexed protein analysis through the use of microarrays, reliable molecules capable of specifically binding to a protein of interest with high…”
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Cerebral Sinus Thrombosis in a 6-Year-Old Boy After a Minor Head Injury by Lebowitz, David C, Ko, Melissa W, Cameron, Ella K, Ko, Paul Y

“…ABSTRACTPosttraumatic cerebral sinus thrombosis is an uncommon disease in children that is rarely seen in the setting of a closed head injury. We report a…”
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Label-Free Sub-picomolar Protein Detection with Field-Effect Transistors by Estrela, Pedro, Paul, Debjani, Song, Qifeng, Stadler, Lukas K. J, Wang, Ling, Huq, Ejaz, Davis, Jason J, Ferrigno, Paul Ko, Migliorato, Piero

“…Proteins mediate the bulk of biological activity and are powerfully assayed in the diagnosis of diseases. Protein detection relies largely on antibodies, which…”
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Label-free electrical detection of DNA hybridization for the example of influenza virus gene sequences by Kukol, Andreas, Li, Peng, Estrela, Pedro, Ko-Ferrigno, Paul, Migliorato, Piero

“…Microarrays based on DNA–DNA hybridization are potentially useful for detecting and subtyping viruses but require fluorescence labeling and imaging equipment…”
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