Search Results - "Ko, Kisung"
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Expression of a Large Single-Chain 13F6 Antibody with Binding Activity against Ebola Virus-Like Particles in a Plant System
Published in International journal of molecular sciences (01-10-2020)“…Pathogenic animal and human viruses present a growing and persistent threat to humans worldwide. Ebola virus (EBOV) causes zoonosis in humans. Here, two…”
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2
Endoplasmic reticulum retention motif fused to recombinant anti-cancer monoclonal antibody (mAb) CO17-1A affects mAb expression and plant stress response
Published in PloS one (24-09-2018)“…The endoplasmic reticulum (ER) is the main site of protein synthesis, folding, and secretion to other organelles. The capacity of the ER to process proteins is…”
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Expression and In Vitro Function of Anti-Breast Cancer Llama-Based Single Domain Antibody VHH Expressed in Tobacco Plants
Published in International journal of molecular sciences (17-02-2020)“…Overexpression of human epidermal growth factor receptor type 2 (HER2) is considered as a prognostic factor of breast cancer, which is positively associated…”
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4
Enhanced Luminescent Detection of Circulating Tumor Cells by a 3D Printed Immunomagnetic Concentrator
Published in Biosensors (Basel) (17-08-2021)“…Circulating tumor cells (CTCs) are an indicator of metastatic progression and relapse. Since non-CTC cells such as red blood cells outnumber CTCs in the blood,…”
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5
Application of Engineered Zinc Finger Proteins Immobilized on Paramagnetic Beads for Multiplexed Detection of Pathogenic DNA
Published in Journal of microbiology and biotechnology (28-09-2021)“…Micro-scale magnetic beads are widely used for isolation of proteins, DNA, and cells, leading to the development of in vitro diagnostics. Efficient isolation…”
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Anticancer effects of different seaweeds on human colon and breast cancers
Published in Marine Drugs (24-09-2014)“…Seafoods and seaweeds represent some of the most important reservoirs of new therapeutic compounds for humans. Seaweed has been shown to have several…”
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Effect of plasma-activated water on peanut seed germination and vegetative growth in a hydroponic system
Published in Plant biotechnology reports (01-08-2023)“…Peanut sprouts have recently been reported to be rich in some nutrients, including vitamin C, resveratrol, antioxidants, and folate, and are consumed as…”
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A Plant-Derived Antigen-Antibody Complex Induces Anti-Cancer Immune Responses by Forming a Large Quaternary Structure
Published in International journal of molecular sciences (05-08-2020)“…The antigen-antibody complex (AAC) has novel functions for immunomodulation, encouraging the application of diverse quaternary protein structures for…”
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Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibody
Published in PloS one (15-08-2013)“…Plant genetic engineering, which has led to the production of plant-derived monoclonal antibodies (mAb(P)s), provides a safe and economically effective…”
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Effect of IgG Fc-fusion and KDEL-ER retention signal on prostate-specific antigen expression in plant and its immune in mice
Published in Plant biotechnology reports (01-12-2022)“…Prostate-specific antigen (PSA) is a protein highly expressed in cancer cells of the prostate gland. In this study, the PSA recombinant protein was fused to…”
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11
Specific binding of plant-expressed anti-PD-L1 monoclonal antibody to multiple myeloma cell line RPMI8226
Published in Plant biotechnology reports (01-12-2023)“…Multiple myeloma (MM) is an incurable disease characterized by malignant plasma cells within the bone marrow, and its increasing occurrence has highlighted the…”
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12
Generation of human androgenetic induced pluripotent stem cells
Published in Scientific reports (27-02-2020)“…In humans, parthenogenesis and androgenesis occur naturally in mature cystic ovarian teratomas and androgenetic complete hydatidiform moles (CHM),…”
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13
Expression, function, and glycosylation of anti-colorectal cancer large single-chain antibody (LSC) in plant
Published in Plant biotechnology reports (01-06-2020)“…In this study, transgenic tobacco plants were generated to express anti-colorectal cancer large single chain (LSC) antibody CO17-1A (LSC CO) and LSC CO tagged…”
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Single-cell transcriptome sequencing of plant leaf expressing anti-HER2 VHH–FcK cancer therapeutic protein
Published in Scientific data (19-12-2023)“…The transgenic plant is a promising strategy for the production of highly valuable biotherapeutic proteins such as recombinant vaccines and antibodies. To…”
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15
Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant
Published in PeerJ (San Francisco, CA) (07-04-2021)“…Immunization with thetumor-associated antigen GA733 glycoprotein, which is highly expressed in colorectal cancer, is considered to be a promising strategy for…”
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Expression and in vitro function of anti-PD-L1 human antibody expressed in plant
Published in Plant biotechnology reports (01-08-2023)“…Plants can be used to produce recombinant functional proteins such as antibodies and vaccines. In this study, transgenic plants were utilized to express…”
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Production of Monoclonal Antibodies in Plants for Cancer Immunotherapy
Published in BioMed research international (01-01-2015)“…Plants are considered as an alternative platform for recombinant monoclonal antibody (mAb) production due to the improvement and diversification of transgenic…”
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Structure of PAP-IgM FcK fusion protein with J-chain expressed in transgenic plant
Published in The eurobiotech journal (01-01-2023)“…Transgenic plants expressing immunoglobulin (Ig) M Fc-fused Prostate acid phosphatase (PAP) antigenic proteins (PAP-IgM FcK) and J-chain proteins were…”
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Transient Plant Expression of Recombinant Rabies Virus Glycoprotein: A strategy for Vaccine Production
Published in Weon'ye gwahag gi'sulji (01-01-2024)“…The rabies virus causes neurological infections, resulting in the deaths of over 60,000 people worldwide each year. Currently available rabies vaccines are…”
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AFM probing the mechanism of synergistic effects of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) with cefotaxime against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli
Published in PloS one (13-11-2012)“…Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae poses serious challenges to clinicians because of its resistance to many classes of…”
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