Search Results - "Ko, Jung Hwa"

The Anti‐Inflammatory and Anti‐Angiogenic Role of Mesenchymal Stem Cells in Corneal Wound Healing Following Chemical Injury by Oh, Joo Youn, Kim, Mee Kum, Shin, Mi Sun, Lee, Hyun Ju, Ko, Jung Hwa, Wee, Won Ryang, Lee, Jin Hak

“…To investigate the anti‐inflammatory and anti‐angiogenic effects of mesenchymal stem cells (MSC) in the chemically burned corneas, we mechanically removed the…”
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Intravitreal TSG-6 suppresses laser-induced choroidal neovascularization by inhibiting CCR2+ monocyte recruitment by Jin Kim, Sang, Ju Lee, Hyun, Yun, Ji-Hyun, Hwa Ko, Jung, Choi, Da Ye, Youn Oh, Joo

“…Choroidal neovascularization (CNV) is the hallmark of wet age-related macular degeneration (AMD), one of the leading causes of blindness in the elderly…”
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Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis by Ko, Jung Hwa, Kim, Hyeon Ji, Jeong, Hyun Jeong, Lee, Hyun Ju, Oh, Joo Youn

“…The cross-talk between mesenchymal stem and stromal cells (MSCs) and macrophages is critical for the restoration of tissue homeostasis after injury. Here, we…”
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Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye by Ko, Jung Hwa, Lee, Hyun Ju, Jeong, Hyun Jeong, Kim, Mee Kum, Wee, Won Ryang, Yoon, Sun-ok, Choi, Hosoon, Prockop, Darwin J., Oh, Joo Youn

“…Intravenously administered mesenchymal stem/stromal cells (MSCs) engraft only transiently in recipients, but confer long-term therapeutic benefits in patients…”
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The Effect of miR-146a on the Gene Expression of Immunoregulatory Cytokines in Human Mesenchymal Stromal Cells by Ko, Jung Hwa, Oh, Joo Youn

“…Mounting evidence indicates that microRNAs (miRNAs), including miR-146a, have an impact on the immunomodulatory activities of mesenchymal stem/stromal cells…”
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Myeloid cells protect corneal nerves against sterile injury through negative-feedback regulation of TLR2-IL-6 axis by Lee, Hyun Ju, Kim, Hyeon Ji, Ko, Jung Hwa, Oh, Joo Youn

“…Mounting evidence suggests that the immune system plays detrimental or protective roles in nerve injury and repair. Herein we report that both CD11b Ly6G and…”
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Mesenchymal Stem/Stromal Cells Inhibit the NLRP3 Inflammasome by Decreasing Mitochondrial Reactive Oxygen Species by Oh, Joo Youn, Ko, Jung Hwa, Lee, Hyun Ju, Yu, Ji Min, Choi, Hosoon, Kim, Mee Kum, Wee, Won Ryang, Prockop, Darwin J.

“…Mesenchymal stem/stromal cells (MSCs) control excessive inflammatory responses by modulating a variety of immune cells including monocytes/macrophages…”
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Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner by Song, Hyun Beom, Park, Se Yeon, Ko, Jung Hwa, Park, Jong Woo, Yoon, Chang Ho, Kim, Dong Hyun, Kim, Jeong Hun, Kim, Mee Kum, Lee, Ryang Hwa, Prockop, Darwin J., Oh, Joo Youn

“…The cornea is a transparent tissue devoid of blood and lymphatic vessels. However, various inflammatory conditions can cause hemangiogenesis and…”
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Mesenchymal Stem/Stromal Cells Protect the Ocular Surface by Suppressing Inflammation in an Experimental Dry Eye by Lee, Min Joung, Ko, Ah Young, Ko, Jung Hwa, Lee, Hyun Ju, Kim, Mee Kum, Wee, Won Ryang, Khwarg, Sang In, Oh, Joo Youn

“…Dry eye syndrome (DES) is one of the most common ocular diseases affecting nearly 10% of the US population. Most of the currently available treatments are…”
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Inhibition of Aberrant α(1,2)-Fucosylation at Ocular Surface Ameliorates Dry Eye Disease by Yoon, Chang Ho, Ryu, Jin Suk, Ko, Jung Hwa, Oh, Joo Youn

“…Fucosylation is involved in a wide range of biological processes from cellular adhesion to immune regulation. Although the upregulation of fucosylated glycans…”
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Effects of 20% Human Serum on Corneal Epithelial Toxicity Induced by Benzalkonium Chloride: In Vitro and Clinical Studies by Moon, Jayoon, Ko, Jung Hwa, Yoon, Chang Ho, Kim, Mee Kum, Oh, Joo Youn

“…PURPOSE:Benzalkonium chloride (BAK), the most commonly used preservative in ophthalmic solutions, is known to cause toxicity in the corneal epithelium. In this…”
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The Eyelid Meibomian Gland Deficiency in Fucosyltransferase 1 Knockout Mice by Yoon, Chang Ho, Ryu, Jin Suk, Ko, Jung Hwa, Kim, Yeon Kyung, Oh, Jang-Hee, Chung, Jin Ho, Oh, Joo Youn

“…To investigate the effect of fucosyltransferase (FUT) 1-mediated fucosylation on meibomian glands (MG), we first confirmed that FUT1 and its fucosylated…”
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Prednisolone induces apoptosis in corneal epithelial cells through the intrinsic pathway by Ryu, Jin Suk, Ko, Jung Hwa, Kim, Mee Kum, Wee, Won Ryang, Oh, Joo Youn

“…Glucocorticoid eye drops are one of the most widely used medications in ophthalmology. However, little is known about the effects of glucocorticoids on corneal…”
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Interferon-γ elicits the ocular surface pathology mimicking dry eye through direct modulation of resident corneal cells by Ko, Jung Hwa, Kim, Seonghwan, Ryu, Jin Suk, Song, Hyo Jeong, Oh, Joo Youn

“…Despite accumulating evidence indicating a key role of interferon-γ (IFN-γ)-producing immune cells in ocular infection and immunity, little is known about the…”
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Comparison of the anti-inflammatory effects of induced pluripotent stem cell–derived and bone marrow–derived mesenchymal stromal cells in a murine model of corneal injury by Yun, Young In, Park, Se Yeon, Lee, Hyun Ju, Ko, Jung Hwa, Kim, Mee Kum, Wee, Won Ryang, Reger, Roxanne L, Gregory, Carl A, Choi, Hosoon, Fulcher, Samuel F, Prockop, Darwin J, Oh, Joo Youn

“…Abstract Background aims Mesenchymal stromal cells (MSCs) offer tremendous potential for therapeutic applications for inflammatory diseases. However,…”
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The role of cyclosporine and mycophenolate in an orthotopic porcine-to-rat corneal xenotransplantation by Lee, Hyeon Il, Kim, Mee Kum, Oh, Joo Youn, Ko, Jung Hwa, Lee, Hyun Ju, Wee, Won Ryang, Lee, Jin Hak

“…We performed this study to investigate the feature of rejection in porcine-to-rat corneal orthotopic transplantation and to evaluate the effect of cyclosporine…”
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Analysis of macrophage phenotype in rejected corneal allografts by Oh, Joo Youn, Lee, Hyun Ju, Ko, Ah Young, Ko, Jung Hwa, Kim, Mee Kum, Wee, Won Ryang

“…We investigated the phenotype of macrophages infiltrating rejected corneal allografts. We performed allogeneic or syngeneic corneal transplantation in mice,…”
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Stanniocalcin-1 protects retinal ganglion cells by inhibiting apoptosis and oxidative damage by Kim, Sang Jin, Ko, Jung Hwa, Yun, Ji-Hyun, Kim, Ju-A, Kim, Tae Eun, Lee, Hyun Ju, Kim, Seok Hwan, Park, Ki Ho, Oh, Joo Youn

“…Optic neuropathy including glaucoma is one of the leading causes of irreversible vision loss, and there are currently no effective therapies. The hallmark of…”
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Neonatal systemic inflammation in rats alters retinal vessel development and simulates pathologic features of retinopathy of prematurity by Hong, Hye Kyoung, Lee, Hyun Ju, Ko, Jung Hwa, Park, Ji Hyun, Park, Ji Yeon, Choi, Chang Won, Yoon, Chang-Hwan, Ahn, Seong Joon, Park, Kyu Hyung, Woo, Se Joon, Oh, Joo Youn

“…Alteration of retinal angiogenesis during development leads to retinopathy of prematurity (ROP) in preterm infants, which is a leading cause of visual…”
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Surgical and obstetric outcomes of laparoscopic management for women with heterotopic pregnancy by Eom, Jeong Min, Choi, Joong Sub, Ko, Jung Hwa, Lee, Jung Hun, Park, Seon Hye, Hong, Jin Hwa, Hur, Chang Young

“…Aim The aim of this study was to investigate the obstetric outcomes and clinical efficacy of laparoscopic surgery for women with heterotopic pregnancy…”
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