Search Results - "Ko, Jihye"

Efficacious, safe, and stable inhibition of corneal neovascularization by AAV-vectored anti-VEGF therapeutics by Su, Wenqi, Sun, Shuo, Tian, Bo, Tai, Phillip W.L., Luo, Yongwen, Ko, Jihye, Zhan, Wei, Ke, Xiao, Zheng, Qiang, Li, Xiaorong, Yan, Hua, Gao, Guangping, Lin, Haijiang

“…Corneal neovascularization (CoNV) leads to visual impairment, affecting over 1.4 million people in the United States per year. It is caused by a variety of…”
Get full text

Coagulation factor IX gene transfer to non-human primates using engineered AAV3 capsid and hepatic optimized expression cassette by Kumar, Sandeep R.P., Xie, Jun, Hu, Shilang, Ko, Jihye, Huang, Qifeng, Brown, Harrison C., Srivastava, Alok, Markusic, David M., Doering, Christopher B., Spencer, H. Trent, Srivastava, Arun, Gao, Guangping, Herzog, Roland W.

“…Hepatic gene transfer with adeno-associated viral (AAV) vectors shows much promise for the treatment of the X-linked bleeding disorder hemophilia B in multiple…”
Get full text

Low-Dose Recombinant Adeno-Associated Virus-Mediated Inhibition of Vascular Endothelial Growth Factor Can Treat Neovascular Pathologies Without Inducing Retinal Vasculitis by Cheng, Shun-Yun, Luo, Yongwen, Malachi, Anneliese, Ko, Jihye, Su, Qin, Xie, Jun, Tian, Bo, Lin, Haijiang, Ke, Xiao, Zheng, Qiang, Tai, Phillip W L, Gao, Guangping, Punzo, Claudio

“…The wet form of age-related macular degeneration is characterized by neovascular pathologies that, if untreated, can result in edemas followed by rapid vision…”
Get more information

Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold by Xie, Jun, Tai, Phillip W.L., Brown, Alexander, Gong, Shoufang, Zhu, Sha, Wang, Yi, Li, Chengjian, Colpan, Cansu, Su, Qin, He, Ran, Ma, Hong, Li, Jia, Ye, Hanqing, Ko, Jihye, Zamore, Phillip D., Gao, Guangping

“…Short hairpin RNAs that are delivered by recombinant adeno-associated virus (rAAV) have the potential to elicit long-term RNAi therapy for human disease…”
Get full text