Search Results - "Ko, Je Yeong"

Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development by Ko, Je Yeong, Oh, Sumin, Yoo, Kyung Hyun

“…Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer…”
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Mouse models of polycystic kidney disease induced by defects of ciliary proteins by Ko, Je Yeong, Park, Jong Hoon

“…Polycystic kidney disease (PKD) is a common hereditary disorder which is characterized by fluid-filled cysts in the kidney. Mutation in either PKD1, encoding…”
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Deficiency of calpain-6 inhibits primary ciliogenesis by Kim, Bo Hye, Kim, Do Yeon, Oh, Sumin, Ko, Je Yeong, Rah, Gyuyeong, Yoo, Kyung Hyun, Park, Jong Hoon

“…The primary cilium is a microtubule-based structure projecting from a cell. Although the primary cilium shows no motility, it can recognize environmental…”
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Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer by Ko, Je Yeong, Lee, Eun Ji, Park, Jong Hoon

“…Primary cilia and autophagy are two distinct nutrient-sensing machineries required for maintaining intracellular energy homeostasis, either via signal…”
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Targeting of miR34a-NOTCH1 axis reduced breast cancer stemness and chemoresistance by Park, Eun Young, Chang, EunSun, Lee, Eun Ji, Lee, Hyun-Woo, Kang, Hyeok-Gu, Chun, Kyung-Hee, Woo, Yu Mi, Kong, Hyun Kyung, Ko, Je Yeong, Suzuki, Hiromu, Song, Erwei, Park, Jong Hoon

“…Human breast cancers include cancer stem cell populations as well as nontumorigenic cancer cells. Breast cancer stem cells have self-renewal capability and are…”
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Autophagy inhibits cancer stemness in triple‐negative breast cancer via miR‐181a‐mediated regulation of ATG5 and/or ATG2B by Park, Jee Won, Kim, Yesol, Lee, Soo‐been, Oh, Chae Won, Lee, Eun Ji, Ko, Je Yeong, Park, Jong Hoon

“…Autophagy has a dual role in the maintenance of cancer stem cells (CSCs), but the precise relationship between autophagy and cancer stemness requires further…”
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Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli by Jun, Jae Hee, Lee, Eun Ji, Park, Minah, Ko, Je Yeong, Park, Jong Hoon

“…Renal primary cilia are antenna-like organelles that maintain cellular homeostasis via multiple receptors clustered along their membranes. Recent studies have…”
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Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer by Ko, Je Yeong, Lee, Eun Ji, Park, Jong Hoon

“…Primary cilia and autophagy are two distinct nutrient-sensing machineries required for maintaining intracellular energy homeostasis, either via signal…”
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Mxi1 influences cyst formation in three-dimensional cell culture by Yook, Y.J., Sookmyung Women's University, Seoul, Republic of Korea, Yoo, K.H., Sookmyung Women's University, Seoul, Republic of Korea, Song, S.A., Sookmyung Women's University, Seoul, Republic of Korea, Seo, M.J., Sookmyung Women's University, Seoul, Republic of Korea, Ko, J.Y., Sookmyung Women's University, Seoul, Republic of Korea, Kim, B.H., Sookmyung Women's University, Seoul, Republic of Korea, Lee, E.J., Sookmyung Women's University, Seoul, Republic of Korea, Chang, E.S., Sookmyung Women's University, Seoul, Republic of Korea, Woo, Y.M., Sookmyung Women's University, Seoul, Republic of Korea, Park, J.H., Sookmyung Women's University, Seoul, Republic of Korea

“…Cyst formation is a major characteristic of ADPKD and is caused by the abnormal proliferation of epithelial cells. Renal cyst formation disrupts renal function…”
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Soluble receptor for advanced glycation end products inhibits disease progression in autosomal dominant polycystic kidney disease by down‐regulating cell proliferation by Lee, Eun Ji, Park, Eun Young, Mun, HyoWon, Chang, EunSun, Ko, Je Yeong, Kim, Do Yeon, Park, Jong Hoon

“…Autosomal polycystic kidney disease (ADPKD) is a highly prevalent genetic renal disorder in which epithelial‐lining fluid‐filled cysts appear in kidneys. It is…”
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Autophagy induction promotes renal cyst growth in polycystic kidney disease by Lee, Eun Ji, Ko, Je Yeong, Oh, Sumin, Jun, Jaehee, Mun, Hyowon, Lim, Chae Ji, Seo, Seungwoon, Ko, Hyuk Wan, Kim, Hyunho, Oh, Yun Kyu, Ahn, Curie, Kang, Minyong, Kim, Min Jung, Yoo, Kyung Hyun, Oh, Goo Taeg, Park, Jong Hoon

“…Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been recently suggested as a potential therapeutic…”
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Mouse models of polycystic kidney disease induced by defects of ciliary proteins by Ko, J.Y., Womens University, Seoul , Republic of Korea, Park, J.H., Womens University, Seoul , Republic of Korea

“…Polycystic kidney disease (PKD) is a common hereditary disorder which is characterized by fluid-filled cysts in the kidney. Mutation in either PKD1, encoding…”
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Mxi1 influences cyst formation in three-dimensional cell culture by Yook, Yeon-Joo, Yoo, Kyung-Hyun, Song, Seon-Ah, Seo, Min-Ji, Ko, Je-Yeong, Kim, Bo-Hye, Lee, Eun-Ji, Chang, Eun-Sun, Woo, Yu-Mi, Park, Jong-Hoon

“…Cyst formation is a major characteristic of ADPKD and is caused by the abnormal proliferation of epithelial cells. Renal cyst formation disrupts renal function…”
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Epigenetic activation of LY6K predicts the presence of metastasis and poor prognosis in breast carcinoma by Kong, Hyun Kyung, Park, Sae Jeong, Kim, Ye Sol, Kim, Kyoung Min, Lee, Hyun-Woo, Kang, Hyeok-Gu, Woo, Yu Mi, Park, Eun Young, Ko, Je Yeong, Suzuki, Hiromu, Chun, Kyung-Hee, Song, Erwei, Jang, Kyu Yun, Park, Jong Hoon

“…The role of lymphocyte antigen 6 complex, locus K (LY6K) in breast cancer has been studied, whereas the epigenetic control of LY6K transcription is not fully…”
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IFT46 plays an essential role in cilia development by Lee, Mi-Sun, Hwang, Kyu-Seok, Oh, Hyun-Woo, Ji-Ae, Kim, Kim, Hyun-Taek, Cho, Hyun-Soo, Lee, Jeong-Ju, Yeong Ko, Je, Choi, Jung-Hwa, Jeong, Yun-Mi, You, Kwan-Hee, Kim, Joon, Park, Doo-Sang, Nam, Ki-Hoan, Aizawa, Shinichi, Kiyonari, Hiroshi, Shioi, Go, Park, Jong-Hoon, Zhou, Weibin, Kim, Nam-Soon, Kim, Cheol-Hee

“…Cilia are microtubule-based structures that project into the extracellular space. Ciliary defects are associated with several human diseases, including…”
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Up-regulation of Idh3 α causes reduction of neuronal differentiation in PC12 cells by Cho, Sun-A, Seo, Min-Ji, Ko, Je-Yeong, Shim, Jung-Hee, Yoo, Jin, Kim, Jung-Hee, Kim, Se-Yoon, Ryu, Na-Kyung, Park, Eun-Young, Lee, Han-Woong, Lee, Yeon-Su, Bahk, Young-Yil, Park, Jong-Hoon

“…The PC12 is the widely used cell line to study neuronal differentiation. We had extensively investigated the details of protein expression in differentiated…”
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Differential Expression of $PKD2$-Associated Genes in Autosomal Dominant Polycystic Kidney Disease by Yook, Yeon-Joo, Woo, Yu-Mi, Yang, Moon-Hee, Ko, Je-Yeong, Kim, Bo-Hye, Lee, Eun-Ji, Chang, Eun-Sun, Lee, Min-Joo, Lee, Sun-Young, Park, Jong-Hoon

“…Autosomal dominant polycystic kidney disease (ADPKD) is characterized by formation of multiple fluid-filled cysts that expand over time and destroy renal…”
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Transcriptional programming of pathogenic genes in polycystic kidney disease by Ko, Je Yeong, Park, Jong Hoon

“…Transcriptional dysregulation is a prominent contributor to the pathogenesis of autosomal dominant polycystic kidney disease. Lakhia et al. identified an…”
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Cilk1 Deficiency Induces Cyst Formation and Abnormal Ciliary Trafficking via Klc3: FR-PO276 by Ko, Je Yeong, Rah, Gyuyeong, Park, Jong Hoon

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Functional Study of the Primary Cilia in ADPKD by Ko, Je Yeong

“…The primary cilium is a microtubule-based organelle that is considered to be a cellular antennae, because proteins related to multiple signaling pathways such…”
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