Search Results - "Ko, Chiew"

Reduced Immunopathology and Mortality Despite Tissue Persistence in a Mycobacterium tuberculosis Mutant Lacking Alternative σ Factor, SigH by Kaushal, Deepak, Schroeder, Benjamin G., Tyagi, Sandeep, Yoshimatsu, Tetsuyuki, Scott, Cherise, Ko, Chiew, Carpenter, Liane, Mehrotra, Jyoti, Manabe, Yukari C., Fleischmann, Robert D., Bishai, William R.

“…The pathogenesis of tuberculosis involves multiple phases and is believed to involve both a carefully deployed series of adaptive bacterial virulence factors…”
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Mycobacterium tuberculosis ECF sigma factor sigC is required for lethality in mice and for the conditional expression of a defined gene set by Sun, Ronggai, Converse, Paul J., Ko, Chiew, Tyagi, Sandeep, Morrison, Norman E., Bishai, William R.

“…Summary Bacterial alternative RNA polymerase sigma factors are key global adaptive response regulators with a likely role in Mycobacterium tuberculosis…”
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The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome‐associated gene products in stationary phase and is required for full virulence by Calamita, Heather, Ko, Chiew, Tyagi, Sandeep, Yoshimatsu, Tetsuyuki, Morrison, Norman E., Bishai, William R.

“…Summary During infection Mycobacterium tuberculosis is exposed to several environmental conditions depending on the stage and severity of the disease. To…”
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Absence of mycobacterium avium subsp. paratuberculosis in Crohn's patients by Parrish, Nicole M., Radcliff, Roy P., Brey, Becky J., Anderson, Jennifer L., Clark, Dorn L., Koziczkowski, Jeff J., Ko, Chiew G., Goldberg, Neil D., Brinker, David A., Carlson, Robert A., Dick, James D., Ellingson, Jay L.E.

“…Background: Mycobacterium avium subspecies paratuberculosis (MAP) has been suspected of involvement in Crohn's disease (CD). We investigated this potential…”
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Deletion of Mycobacterium tuberculosis Sigma Factor E Results in Delayed Time to Death with Bacterial Persistence in the Lungs of Aerosol-Infected Mice by ANDO, Masaru, YOSHIMATSU, Tetsuyuki, CHIEW KO, CONVERSE, Paul J, BISHAI, William R

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Activity of DSA against anaerobically adapted Mycobacterium bovis BCG in vitro by Parrish, Nicole M, Ko, Chiew G, Dick, James D

“…Summary DSA is a β-sulfonylacetamide with in vitro activity against pathogenic mycobacteria. Although the enzymatic target(s) of DSA has not been identified,…”
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Attenuation of Late-Stage Disease in Mice Infected by the Mycobacterium tuberculosis Mutant Lacking the SigF Alternate Sigma Factor and Identification of SigF-Dependent Genes by Microarray Analysis by GEIMAN, Deborah E, KAUSHAL, Deepak, BISHAI, William R, KO, Chiew, TYAGI, Sandeep, MANABE, Yukari C, SCHROEDER, Benjamin G, FLEISCHMANN, Robert D, MORRISON, Norman E, CONVERSE, Paul J, PING CHEN

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Exposure to antibiotics induces expression of the Mycobacterium tuberculosis sigF gene : Implications for chemotherapy against mycobacterial persistors by MICHELE, T. M, CHIEW KO, BISHAI, W. R

“…The sigF gene encodes an alternate sigma factor found in Mycobacterium tuberculosis and related pathogenic mycobacteria. Determination of conditions of sigF…”
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The Staphylococcus aureus rsbW(orf159) Gene Encodes an Anti-Sigma Factor of SigB by Miyazaki, E, Chen, J M, Ko, C, Bishai, W R

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Conditional Sigma Factor Expression, Using the Inducible Acetamidase Promoter, Reveals that the Mycobacterium tuberculosis sigF Gene Modulates Expression of the 16-Kilodalton Alpha-Crystallin Homologue by Manabe, Y C, Chen, J M, Ko, C G, Chen, P, Bishai, W R

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Growth, Congo Red Agar Colony Morphotypes and Antibiotic Susceptibility Testing of Mycobacterium avium subspecies paratuberculosis by Parrish, Nicole M, Ko, Chiew G, Dick, James D, Jones, Paul B, Ellingson, Jay L E

“…Mycobacterium avium subspecies (subsp.) paratuberculosis (MAP) is the causative agent of Johne's disease in ruminants and has been associated with Crohn's…”
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Exposure to Antibiotics Induces Expression of theMycobacterium tuberculosis sigF Gene: Implications for Chemotherapy against Mycobacterial Persistors by Michele, Theresa M, Ko, Chiew, Bishai, William R

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Neutrophil adhesion molecule expression during cardiopulmonary bypass with bubble and membrane oxygenators by Gillinov, A.Marc, Bator, Jenny M., Zehr, Kenton J., Redmond, J.Mark, Burch, Ronald M., Ko, Chiew, Winkelstein, Jerry A., Stuart, R.Scott, Baumgartner, William A., Cameron, Duke E.

“…The neutrophil-mediated tissue injury associated with cardiopulmonary bypass (CPB) is thought to require the interaction of specific neutrophil and endothelial…”
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Effect of n-octanesulphonylacetamide (OSA) on ATP and protein expression in Mycobacterium bovis BCG by Parrish, Nicole M., Ko, Chiew G., Hughes, Minerva A., Townsend, Craig A., Dick, James D.

“…Objective: To determine the effect on BCG of n-octanesulphonylacetamide (OSA), a novel compound of the class β-sulphonylcarboxamides, which has potent in vitro…”
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Evaluation of a Whole-Blood Interferon-γ Release Assay for the Detection of Mycobacterium tuberculosis Infection in 2 Study Populations by Bellete, Bahrie, Coberly, Jacqueline, Link Barnes, Grace, Ko, Chiew, Chaisson, Richard E., Comstock, George W., Bishai, William R.

“…A whole-blood interferon-γ release assay (IGRA) is being evaluated for its potential to replace the tuberculin skin test (TST) for detecting Mycobacterium…”
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A Stationary-Phase Stress-Response Sigma Factor from Mycobacterium tuberculosis by DeMaio, James, Zhang, Ying, Ko, Chiew, Young, Douglas B., Bishai, William R.

“…Alternative RNA polymerase sigma factors are a common means of coordinating gene regulation in bacteria. Using PCR amplification with degenerate primers, we…”
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Effect ofn-octanesulphonylacetamide (OSA) on ATP and protein expression in Mycobacterium bovis BCG by Parrish, Nicole M., Ko, Chiew G., Hughes, Minerva A., Townsend, Craig A., Dick, James D.

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The Mycobacterium tuberculosis SigD sigma factor controls the expression of ribosome-associated gene products in stationary phase and is required for full virulence: Mycobacterium tuberculosis sigma factor SigD by Calamita, Heather, Ko, Chiew, Tyagi, Sandeep, Yoshimatsu, Tetsuyuki, Morrison, Norman E., Bishai, William R.

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Deletionof Mycobacterium tuberculosis Sigma Factor E Results inDelayed Time to Death with Bacterial Persistence in the Lungsof Aerosol-InfectedMice by Ando, Masaru, Yoshimatsu, Tetsuyuki, Ko, Chiew, Converse, Paul J., Bishai, William R.

“…The stress-induced extracytoplasmic sigma factor E (SigE) of Mycobacterium tuberculosis shows increased expression after heat shock, sodium dodecyl sulfate…”
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Attenuation of Late-Stage Disease in Mice Infected bythe Mycobacterium tuberculosis Mutant Lacking theSigF Alternate Sigma Factor and Identification ofSigF-Dependent Genes by MicroarrayAnalysis by Geiman, Deborah E., Kaushal, Deepak, Ko, Chiew, Tyagi, Sandeep, Manabe, Yukari C., Schroeder, Benjamin G., Fleischmann, Robert D., Morrison, Norman E., Converse, Paul J., Chen, Ping, Bishai, William R.

“…The Mycobacterium tuberculosis alternate sigma factor, SigF, is expressed during stationary growth phase and under stress conditions in vitro. To better…”
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