Search Results - "Ko, Ben C. B."

Sirtuin 1 Regulates Hepatitis B Virus Transcription and Replication by Targeting Transcription Factor AP-1 by Ren, Ji-Hua, Tao, Ying, Zhang, Zhen-Zhen, Chen, Wei-Xian, Cai, Xue-Fei, Chen, Ke, Ko, Ben C B, Song, Chun-Li, Ran, Long-Kuan, Li, Wan-Yu, Huang, Ai-Long, Chen, Juan

“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells by Zhang, Bin, Chen, Juan, Cheng, Alfred S L, Ko, Ben C B

“…Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that is implicated in plethora of biological processes, including…”
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Inhibition of urease by bismuth(III): implications for the mechanism of action of bismuth drugs by Zhang, Li, Mulrooney, Scott B, Leung, Andy F K, Zeng, Yibo, Ko, Ben B C, Hausinger, Robert P, Sun, Hongzhe

“…Bismuth compounds are widely used for the treatment of peptic ulcers and Helicobacter pylori infections. It has been suggested that enzyme inhibition plays an…”
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Sirtuin 1 Is Upregulated in a Subset of Hepatocellular Carcinomas where It Is Essential for Telomere Maintenance and Tumor Cell Growth by JUAN CHEN, BIN ZHANG, JUN YU, NG, Ho-Keung, LING, Ming-Tat, HUANG, Ai-Long, CAI, Xue-Fei, KO, Ben C. B, WONG, Nathalie, LO, Anthony W. I, TO, Ka-Fai, CHAN, Anthony W. H, NG, Margaret H. L, HO, Cecilia Y. S, CHENG, Suk-Hang, LAI, Paul B. S

“…Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. Treatment of HCC is complicated by the fact that the disease is often…”
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Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress by Tong, Edith H Y, Guo, Jin-Jun, Xu, Song-Xiao, Mak, Keri, Chung, Sookja K, Chung, Stephen S M, Huang, Ali-Long, Ko, Ben C B

“…Osmotic Response Element-Binding Protein (OREBP), also known as TonEBP or NFAT5, is a unique transcription factor. It is hitherto the only known mammalian…”
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Pseudolaric acids: isolation, bioactivity and synthetic studies by Chiu, Pauline, Leung, Lai To, Ko, Ben C B

“…The pseudolaric acids are diterpenoids isolated from the root bark of Pseudolarix amabilis, or the golden larch. Pseudolaric acids A and B are the major…”
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Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms by Wong, Vincent Kam Wai, Zeng, Wu, Chen, Juan, Yao, Xiao Jun, Leung, Elaine Lai Han, Wang, Qian Qian, Chiu, Pauline, Ko, Ben C B, Law, Betty Yuen Kwan

“…Emerging evidence suggests the therapeutic role of autophagic modulators in cancer therapy. This study aims to identify novel traditional Chinese medicinal…”
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Regulation of Nucleocytoplasmic Trafficking of Transcription Factor OREBP/TonEBP/NFAT5 by Tong, Edith H.Y., Guo, Jin-Jun, Huang, Ai-Long, Liu, Han, Hu, Chang-Deng, Chung, Stephen S.M., Ko, Ben C.B.

“…The osmotic response element-binding protein (OREBP), also known as tonicity enhancer-binding protein (TonEBP) or NFAT5, regulates the hypertonicity-induced…”
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Phosphorylation by Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/Tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking by Xu, SongXiao, Wong, Catherine C.L., Tong, Edith H.Y., Chung, Stephen S.M., Yates, John R., Yin, YiBing, Ko, Ben C.B.

“…The osmotic response element-binding protein (OREBP), also known as tonicity enhancer-binding protein (TonEBP) or NFAT5, is the only known osmo-sensitive…”
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RUVBL1/2 Complex Regulates Pro-Inflammatory Responses in Macrophages via Regulating Histone H3K4 Trimethylation by Zhang, Rui, Cheung, Chris Y., Seo, Sang-Uk, Liu, Hang, Pardeshi, Lakhansing, Wong, Koon Ho, Chow, Larry M. C., Chau, Mary P., Wang, Yixiang, Lee, Ah Ra, Kwon, Woon Yong, Chen, Sheng, Chan, Bill Kwan-wai, Wong, Kenneth, Choy, Richard K. W., Ko, Ben C. B.

“…Macrophages play an important role in the host defense mechanism. In response to infection, macrophages activate a genetic program of pro-inflammatory response…”
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Long noncoding RNA ELDR promotes cell cycle progression in normal oral keratinocytes through induction of a CTCF-FOXM1-AURKA signaling axis by Sur, Subhayan, Steele, Robert, Ko, Ben C.B., Zhang, Jinsong, Ray, Ratna B.

“…Long noncoding RNAs (lncRNAs) have gained widespread attention as a new layer of regulation in biological processes during development and disease. The lncRNA…”
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Heparin sulphate d -glucosaminyl 3-O-sulfotransferase 3B1 plays a role in HBV replication by Zhang, Zhenzhen, Liu, Xiang, Chen, Juan, Su, Huaibin, Luo, Qiang, Ye, Jia, Tang, Ni, Zhang, Wenlu, Chen, WeiXian, Ko, Ben C.B, Huang, Ailong

“…Abstract Hepatitis B virus infection is a worldwide epidemic and is closely associated with the development of hepatocellular carcinoma. Nevertheless, the…”
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Unconventional tonicity-regulated nuclear trafficking of NFAT5 mediated by KPNB1, XPOT and RUVBL2 by Cheung, Chris Y, Huang, Ting-Ting, Chow, Ning, Zhang, Shuqi, Zhao, Yanxiang, Chau, Mary P, Chan, Wing Cheung, Wong, Catherine C L, Boassa, Daniela, Phan, Sebastien, Ellisman, Mark H, Yates, John R, Xu, SongXiao, Yu, Zicheng, Zhang, Yajing, Zhang, Rui, Ng, Ling Ling, Ko, Ben C B

“…NFAT5 is the only known mammalian tonicity-responsive transcription factor with an essential role in cellular adaptation to hypertonic stress. It is also…”
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Emerging new role of NFAT5 in inducible nitric oxide synthase in response to hypoxia in mouse embryonic fibroblast cells by Serman, Yair, Fuentealba, Rodrigo A, Pasten, Consuelo, Rocco, Jocelyn, Ko, Ben C B, Carrión, Flavio, Irarrázabal, Carlos E

“…We previously described the protective role of the nuclear factor of activated T cells 5 (NFAT5) during hypoxia. Alternatively, inducible nitric oxide synthase…”
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Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity In vivo by WONG, Vincent K. W, CHIU, Pauline, CHUNG, Stephen S. M, CHOW, Larry M. C, ZHAO, Yun-Zhe, YANG, Burton B, KO, Ben C. B

“…Purpose: Pseudolaric acid B (PAB) is the major bioactive constituent in the root bark of Pseudolarix kaempferi that has been used as an antifungal remedy in…”
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Preparation of N-Sulfonyl- and N-Carbonyl-11-Azaartemisinins with Greatly Enhanced Thermal Stabilities: in vitro Antimalarial Activities by Haynes, Richard K., Wong, Ho-Ning, Lee, Kin-Wo, Lung, Chung-Man, Shek, Lai Yung, Williams, Ian D., Croft, Simon L., Vivas, Livia, Rattray, Lauren, Stewart, Lindsay, Wong, Vincent K. W., Ko, Ben C. B.

“…As the clinically used artemisinins do not withstand the thermal stress testing required to evaluate shelf life for storage in tropical countries where malaria…”
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NFAT5 in cellular adaptation to hypertonic stress - regulations and functional significance by Cheung, Chris Yk, Ko, Ben Cb

“…The Nuclear Factor of Activated T Cells-5 (NFAT5), also known as OREBP or TonEBP, is a member of the nuclear factors of the activated T cells family of…”
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Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus by Ho, Horace T. B., Chung, Sookja K., Law, Janice W. S., Ko, Ben C. B., Tam, Sidney C. F., Brooks, Heddwen L., Knepper, Mark A., Chung, Stephen S. M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Transgenic Mice Expressing Dominant-negative Osmotic-response Element-binding Protein (OREBP) in Lens Exhibit Fiber Cell Elongation Defect Associated with Increased DNA Breaks by Wang, Yu, Ko, Ben C.B., Yang, James Y., Lam, Terrence T.L., Jiang, Zhirong, Zhang, Jinsong, Chung, Sookja K., Chung, Stephen S.M.

“…Osmotic-response element-binding protein (OREBP), also known as TonEBP or NFAT5, is thought to be responsible for the induction of osmolyte-accumulating genes…”
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Osmotic Response Element-binding Protein (OREBP) Is an Essential Regulator of the Urine Concentrating Mechanism by Lam, Amy K M, Ko, Ben C B, Tam, Sidney, Morris, Ryan, Yang, James Y, Chung, Sookja K, Chung, Stephen S M

“…OREBP (osmotic response element-binding protein), also called TonEBP or NFAT5, is thought to induce the expression of genes that increase the accumulation of…”
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