Search Results - "Ko, Ben B C"
-
1
Sirtuin 1 Regulates Hepatitis B Virus Transcription and Replication by Targeting Transcription Factor AP-1
Published in Journal of Virology (01-03-2014)“…Classifications Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
2
Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells
Published in PloS one (08-01-2014)“…Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase that is implicated in plethora of biological processes, including…”
Get full text
Journal Article -
3
Inhibition of urease by bismuth(III): implications for the mechanism of action of bismuth drugs
Published in Biometals (01-10-2006)“…Bismuth compounds are widely used for the treatment of peptic ulcers and Helicobacter pylori infections. It has been suggested that enzyme inhibition plays an…”
Get full text
Journal Article -
4
Sirtuin 1 Is Upregulated in a Subset of Hepatocellular Carcinomas where It Is Essential for Telomere Maintenance and Tumor Cell Growth
Published in Cancer research (Chicago, Ill.) (15-06-2011)“…Hepatocellular carcinoma (HCC) is a highly malignant tumor with a poor prognosis. Treatment of HCC is complicated by the fact that the disease is often…”
Get full text
Journal Article -
5
Inducible nucleosome depletion at OREBP-binding-sites by hypertonic stress
Published in PloS one (24-12-2009)“…Osmotic Response Element-Binding Protein (OREBP), also known as TonEBP or NFAT5, is a unique transcription factor. It is hitherto the only known mammalian…”
Get full text
Journal Article -
6
Pseudolaric acids: isolation, bioactivity and synthetic studies
Published in Natural product reports (01-07-2010)“…The pseudolaric acids are diterpenoids isolated from the root bark of Pseudolarix amabilis, or the golden larch. Pseudolaric acids A and B are the major…”
Get more information
Journal Article -
7
Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms
Published in Frontiers in pharmacology (08-06-2017)“…Emerging evidence suggests the therapeutic role of autophagic modulators in cancer therapy. This study aims to identify novel traditional Chinese medicinal…”
Get full text
Journal Article -
8
Regulation of Nucleocytoplasmic Trafficking of Transcription Factor OREBP/TonEBP/NFAT5
Published in The Journal of biological chemistry (18-08-2006)“…The osmotic response element-binding protein (OREBP), also known as tonicity enhancer-binding protein (TonEBP) or NFAT5, regulates the hypertonicity-induced…”
Get full text
Journal Article -
9
Phosphorylation by Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/Tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking
Published in The Journal of biological chemistry (20-06-2008)“…The osmotic response element-binding protein (OREBP), also known as tonicity enhancer-binding protein (TonEBP) or NFAT5, is the only known osmo-sensitive…”
Get full text
Journal Article -
10
RUVBL1/2 Complex Regulates Pro-Inflammatory Responses in Macrophages via Regulating Histone H3K4 Trimethylation
Published in Frontiers in immunology (04-06-2021)“…Macrophages play an important role in the host defense mechanism. In response to infection, macrophages activate a genetic program of pro-inflammatory response…”
Get full text
Journal Article -
11
Long noncoding RNA ELDR promotes cell cycle progression in normal oral keratinocytes through induction of a CTCF-FOXM1-AURKA signaling axis
Published in The Journal of biological chemistry (01-05-2022)“…Long noncoding RNAs (lncRNAs) have gained widespread attention as a new layer of regulation in biological processes during development and disease. The lncRNA…”
Get full text
Journal Article -
12
Heparin sulphate d -glucosaminyl 3-O-sulfotransferase 3B1 plays a role in HBV replication
Published in Virology (New York, N.Y.) (25-10-2010)“…Abstract Hepatitis B virus infection is a worldwide epidemic and is closely associated with the development of hepatocellular carcinoma. Nevertheless, the…”
Get full text
Journal Article -
13
Unconventional tonicity-regulated nuclear trafficking of NFAT5 mediated by KPNB1, XPOT and RUVBL2
Published in Journal of cell science (01-07-2022)“…NFAT5 is the only known mammalian tonicity-responsive transcription factor with an essential role in cellular adaptation to hypertonic stress. It is also…”
Get full text
Journal Article -
14
Emerging new role of NFAT5 in inducible nitric oxide synthase in response to hypoxia in mouse embryonic fibroblast cells
Published in American Journal of Physiology: Cell Physiology (01-07-2019)“…We previously described the protective role of the nuclear factor of activated T cells 5 (NFAT5) during hypoxia. Alternatively, inducible nitric oxide synthase…”
Get more information
Journal Article -
15
Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity In vivo
Published in Clinical cancer research (15-08-2005)“…Purpose: Pseudolaric acid B (PAB) is the major bioactive constituent in the root bark of Pseudolarix kaempferi that has been used as an antifungal remedy in…”
Get full text
Journal Article -
16
Preparation of N-Sulfonyl- and N-Carbonyl-11-Azaartemisinins with Greatly Enhanced Thermal Stabilities: in vitro Antimalarial Activities
Published in ChemMedChem (08-10-2007)“…As the clinically used artemisinins do not withstand the thermal stress testing required to evaluate shelf life for storage in tropical countries where malaria…”
Get full text
Journal Article -
17
NFAT5 in cellular adaptation to hypertonic stress - regulations and functional significance
Published in Journal of molecular signaling (23-04-2013)“…The Nuclear Factor of Activated T Cells-5 (NFAT5), also known as OREBP or TonEBP, is a member of the nuclear factors of the activated T cells family of…”
Get full text
Journal Article -
18
Aldose Reductase-Deficient Mice Develop Nephrogenic Diabetes Insipidus
Published in Molecular and Cellular Biology (01-08-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
19
Transgenic Mice Expressing Dominant-negative Osmotic-response Element-binding Protein (OREBP) in Lens Exhibit Fiber Cell Elongation Defect Associated with Increased DNA Breaks
Published in The Journal of biological chemistry (20-05-2005)“…Osmotic-response element-binding protein (OREBP), also known as TonEBP or NFAT5, is thought to be responsible for the induction of osmolyte-accumulating genes…”
Get full text
Journal Article -
20
Osmotic Response Element-binding Protein (OREBP) Is an Essential Regulator of the Urine Concentrating Mechanism
Published in The Journal of biological chemistry (12-11-2004)“…OREBP (osmotic response element-binding protein), also called TonEBP or NFAT5, is thought to induce the expression of genes that increase the accumulation of…”
Get full text
Journal Article