Search Results - "Ko, Albert I."
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Global Morbidity and Mortality of Leptospirosis: A Systematic Review
Published in PLoS neglected tropical diseases (17-09-2015)“…Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and…”
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2
Leptospira : the dawn of the molecular genetics era for an emerging zoonotic pathogen
Published in Nature reviews. Microbiology (01-10-2009)“…Key Points Leptospira spp. belong to the bacterial phylum Spirochaetes, an evolutionarily and structurally unique group of bacteria. The genus Leptospira is…”
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3
Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics
Published in Nature biotechnology (01-10-2020)“…We measured severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in primary sewage sludge in the New Haven, Connecticut, USA,…”
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Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study
Published in BMJ (Online) (20-08-2021)“…To estimate the effectiveness of the inactivated whole virus vaccine, CoronaVac (Sinovac Biotech), against symptomatic covid-19 in the elderly population of…”
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Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators
Published in The Journal of immunology (1950) (15-01-2021)“…The COVID-19 pandemic has affected more than 20 million people worldwide, with mortality exceeding 800,000 patients. Risk factors associated with severe…”
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Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination
Published in Nature medicine (01-03-2022)“…The recent emergence of the SARS-CoV-2 Omicron variant is raising concerns because of its increased transmissibility and its numerous spike mutations, which…”
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7
Zika Virus Infection and Stillbirths: A Case of Hydrops Fetalis, Hydranencephaly and Fetal Demise
Published in PLoS neglected tropical diseases (25-02-2016)“…The rapid spread of Zika virus in the Americas and current outbreak of microcephaly in Brazil has raised attention to the possible deleterious effects that the…”
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8
Quantification of Leptospira interrogans Survival in Soil and Water Microcosms
Published in Applied and environmental microbiology (01-07-2018)“…is the etiological agent of leptospirosis, a globally distributed zoonotic disease. Human infection usually occurs through skin exposure with water and soil…”
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Global Burden of Leptospirosis: Estimated in Terms of Disability Adjusted Life Years
Published in PLoS neglected tropical diseases (01-10-2015)“…Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and…”
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10
COVID-19 vulnerability: the potential impact of genetic susceptibility and airborne transmission
Published in Human genomics (12-05-2020)“…The recent coronavirus disease (COVID-19), caused by SARS-CoV-2, is inarguably the most challenging coronavirus outbreak relative to the previous outbreaks…”
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Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil
Published in Nature communications (06-10-2022)“…The effectiveness of inactivated vaccines (VE) against symptomatic and severe COVID-19 caused by omicron is unknown. We conducted a nationwide, test-negative,…”
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12
Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2
Published in Nature communications (06-06-2022)“…The Omicron variant of SARS-CoV-2 recently swept the globe and showed high level of immune evasion. Here, we generate an Omicron-specific lipid nanoparticle…”
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13
Incidence and prevalence of tuberculosis in incarcerated populations: a systematic review and meta-analysis
Published in The Lancet. Public health (01-05-2021)“…Prisons are recognised as high-risk environments for tuberculosis, but there has been little systematic investigation of the global and regional incidence and…”
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14
MPL36, a major plasminogen (PLG) receptor in pathogenic Leptospira, has an essential role during infection
Published in PLoS pathogens (01-07-2023)“…Leptospirosis, a zoonosis with worldwide distribution, is caused by pathogenic spirochetes belonging to the genus Leptospira. Bacterial outer membrane proteins…”
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15
Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19
Published in BMC neurology (18-06-2020)“…COVID-19 is caused by the severe acute respiratory syndrome virus SARS-CoV-2. It is widely recognized as a respiratory pathogen, but neurologic complications…”
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Evaluating strategies for control of tuberculosis in prisons and prevention of spillover into communities: An observational and modeling study from Brazil
Published in PLoS medicine (24-01-2019)“…It has been hypothesized that prisons serve as amplifiers of general tuberculosis (TB) epidemics, but there is a paucity of data on this phenomenon and the…”
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Feasibility and acceptability of a pilot, peer-led HIV self-testing intervention in a hyperendemic fishing community in rural Uganda
Published in PloS one (07-08-2020)“…Background Novel interventions are needed to reach young people and adult men with HIV services given the low HIV testing rates in these population sub-groups…”
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Quantification of pathogenic Leptospira in the soils of a Brazilian urban slum
Published in PLoS neglected tropical diseases (06-04-2018)“…Leptospirosis is an important zoonotic disease that causes considerable morbidity and mortality globally, primarily in residents of urban slums. While contact…”
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Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva
Published in Emerging infectious diseases (01-04-2021)“…The expense of saliva collection devices designed to stabilize severe acute respiratory syndrome coronavirus 2 RNA is prohibitive to mass testing. However,…”
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Patterns in Leptospira Shedding in Norway Rats (Rattus norvegicus) from Brazilian Slum Communities at High Risk of Disease Transmission
Published in PLoS neglected tropical diseases (05-06-2015)“…We address some critical but unknown parameters of individuals and populations of Norway rats (Rattus norvegicus) that influence leptospiral infection,…”
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