Search Results - "Ko, A H"
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A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer
Published in British journal of cancer (20-08-2013)“…Background: PEP02, also known as MM-398, is a novel nanoliposomal irinotecan that has improved pharmacokinetics and tumour bio-distribution of the free drug…”
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Temsirolimus combined with sorafenib in hepatocellular carcinoma: a phase I dose-finding trial with pharmacokinetic and biomarker correlates
Published in Annals of oncology (01-07-2013)“…Based upon preclinical evidence for improved antitumor activity in combination, this phase I study investigated the maximum-tolerated dose (MTD), safety,…”
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A phase 1 trial of imatinib, bevacizumab, and metronomic cyclophosphamide in advanced colorectal cancer
Published in British journal of cancer (01-10-2013)“…Background: This phase 1 clinical trial was conducted to determine the safety, maximum-tolerated dose (MTD), and pharmacokinetics of imatinib, bevacizumab, and…”
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Randomized, double-blind, placebo-controlled phase II study of istiratumab (MM-141) plus nab-paclitaxel and gemcitabine versus nab-paclitaxel and gemcitabine in front-line metastatic pancreatic cancer (CARRIE)
Published in Annals of oncology (01-01-2020)“…Preclinical data suggest that dual blockade of the insulin-like growth factor-1 receptor (IGF-1R) and HER3 pathways has superior activity to IGF-1R blockade…”
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Serum CA19-9 response as a surrogate for clinical outcome in patients receiving fixed-dose rate gemcitabine for advanced pancreatic cancer
Published in British journal of cancer (25-07-2005)“…The use of serial serum measurements of the carbohydrate antigen 19-9 (CA19-9) to guide treatment decisions and serve as a surrogate end point in clinical…”
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Cavitary Pulmonary Lesions in Patients Infected with Human Immunodeficiency Virus
Published in Clinical infectious diseases (01-04-1996)“…The differential diagnosis of cavitary pulmonary lesions in individuals infected with human immunodeficiency virus (HIV) is broad, especially in patients with…”
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A phase I trial of the combination of temsirolimus (TEM) and sorafenib (SOR) in advanced hepatocellular carcinoma (HCC)
Published in Journal of clinical oncology (20-05-2010)“…Abstract only…”
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Hedgehog signaling in gastrointestinal development and disease
Published in Current molecular medicine (01-02-2002)“…The development of the gastrointestinal (GI) tract and its associated parenchymal organs depends on Hedgehog signals from the endoderm to the surrounding…”
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Non-Hodgkin's lymphoma and Kaposi's sarcoma causing cavitary lung lesions in a patient with AIDS: an HIV-associated collision tumor
Published in AIDS (London) (01-10-1995)Get more information
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Kinetic characterization of a prestart cell division control step in yeast. Implications for the mechanism of alpha-factor-induced division arrest
Published in The Journal of biological chemistry (15-12-1990)“…In Saccharomyces cerevisiae yeast, a cycloheximide-sensitive “prestart” step (Ki = 0.12 +/- 0.05 microM) is passaged greater than or equal to 4 to less than or…”
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Corrigendum to ‘Randomized, double-blind, placebo-controlled phase II study of istiratumab (MM-141) plus nab-paclitaxel and gemcitabine versus nab-paclitaxel and gemcitabine in front-line metastatic pancreatic cancer (CARRIE)’: Annals of Oncology, Volume 31, Issue 1, 2020, Pages 79–87
Published in Annals of oncology (01-08-2020)Get full text
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Clinical Outcomes Associated with very Late Relapses in Diffuse Large Cell Lymphoma
Published in Leukemia & lymphoma (2002)“…While the majority of patients achieve complete remission (CR) following treatment for diffuse intermediate-grade and immunoblastic non-Hodgkin's lymphoma,…”
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Community level exposure to chemicals and oxidative stress in adult population
Published in Toxicology letters (30-01-2009)“…Little information is available on the role of environmental chemical exposure in oxidative stress. This study was designed to investigate whether exposure to…”
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Green tea consumption and risk of stomach cancer: A meta‐analysis of epidemiologic studies
Published in International journal of cancer (01-02-2009)“…This meta‐analysis investigated the quantitative association between the consumption of green tea and the risk of stomach cancer in epidemiologic studies using…”
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Acinetobacter species isolates from a range of environments: species survey and observations of antimicrobial resistance
Published in Diagnostic microbiology and infectious disease (01-10-2012)“…Abstract Acinetobacter species isolates from a range of environments, including soil, were investigated. We determined 16S rRNA and rpoB gene sequences for…”
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Nanomedicine developments in the treatment of metastatic pancreatic cancer: focus on nanoliposomal irinotecan
Published in International Journal of Nanomedicine (01-01-2016)“…Nanoliposomal irinotecan (nal-IRI) was originally developed using an efficient and high-loading capacity system to encapsulate irinotecan within a liposomal…”
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Acinetobacter sp. isolates from emergency departments in two hospitals of South Korea
Published in Journal of medical microbiology (01-10-2014)“…A total of 114 Acinetobacter sp. isolates were collected from patients in the emergency departments (EDs) of two Korean hospitals. Most isolates belonged to…”
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