Search Results - "Knutzen, Christine A"
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Control of mTORC1 signaling by the Opitz syndrome protein MID1
Published in Proceedings of the National Academy of Sciences - PNAS (24-05-2011)“…Mutations in the MID1 gene are causally linked to X-linked Opitz BBB/G syndrome (OS), a congenital disorder that primarily affects the formation of diverse…”
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Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect
Published in The Journal of biological chemistry (09-12-2011)“…Metabolic rewiring is an established hallmark of cancer, but the details of this rewiring at a systems level are not well characterized. Here we acquire this…”
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REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase
Published in EMBO reports (01-08-2009)“…The cellular response to hypoxia involves several signalling pathways that mediate adaptation and survival. REDD1 (regulated in development and DNA damage…”
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Comparative Metabolic Flux Profiling of Melanoma Cell Lines
Published in The Journal of biological chemistry (01-12-2011)“…Metabolic rewiring is an established hallmark of cancer, but the details of this rewiring at a systems level are not well characterized. Here we acquire this…”
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Journal Article -
5
Abstract 69: Functional metabolomic profiling of human melanocyte and melanoma cells during hypoxic adaptation
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Adaptation to hypoxia is an important part of the cellular progression from normal melanocyte to malignant melanoma. This adaptation can be comprised of…”
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