Search Results - "Knull, Harvey R"

Brownian Dynamics Simulations of Aldolase Binding Glyceraldehyde 3-Phosphate Dehydrogenase and the Possibility of Substrate Channeling by Ouporov, Igor V., Knull, Harvey R., Huber, Amanda, Thomasson, Kathryn A.

“…Brownian dynamics (BD) simulations test for channeling of the substrate, glyceraldehyde 3-phosphate (GAP), as it passes between the enzymes…”
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Glycolytic Enzyme Interactions with Yeast and Skeletal Muscle F-Actin by Waingeh, Victor F., Gustafson, Carol D., Kozliak, Evguenii I., Lowe, Stephen L., Knull, Harvey R., Thomasson, Kathryn A.

“…Interaction of glycolytic enzymes with F-actin is suggested to be a mechanism for compartmentation of the glycolytic pathway. Earlier work demonstrates that…”
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Brownian Dynamics Simulations of Interactions between Aldolase and G- or F-Actin by Ouporov, Igor V., Knull, Harvey R., Thomasson, Kathryn A.

“…Compartmentation of proteins in cells is important to proper cell function. Interactions of F-actin and glycolytic enzymes is one mechanism by which glycolytic…”
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Location—location—location by Srere, Paul A, Knull, Harvey R

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Glycolytic enzymes and assembly of microtubule networks by Volker, K.Warren, Reinitz, Catharine A., Knull, Harvey R.

“…The ability of glycolytic enzymes, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), aldolase, pyruvate kinase (PK), and lactate dehydrogenase muscle-type (LDH…”
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Effects of nonenzymatic glycation of subfragment-1 of myosin on interactions with actin by Brown, M R, Knull, H R

“…Nonenzymatic bonding of reducing sugars to subfragment-1 of myosin (S-1) resulted in a reduction in actin-activated S-1 ATPase activity. Fructose caused a…”
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The effect of streptozotocin-induced diabetes on glycogen metabolism in rat kidney and its relationship to the liver system by Khandelwal, R L, Zinman, S M, Knull, H R

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Effects of Energy Metabolism on in Vivo Distribution of Hexokinase in Brain by Knull, Harvey R., Taylor, William F., Wells, William W.

“…Hexokinase partitioning between the soluble and mitochondrial fractions of brain has been observed to vary according to the energy status of the brain…”
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A Glycolytic Enzyme Binding Domain on Tubulin by Volker, K.Warren, Knull, Harvey R.

“…Cleavage of tubulin at tryptophan residues yielded several peptides, one of which strongly interacted with aldolase as determined by inhibition of aldolase…”
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Insulin Effects on Brain Energy Metabolism and the Related Hexokinase Distribution by Knull, H R, Taylor, W F, Wells, W W

“…After 11 hours, male chicks (5 days old) injected intraperitoneally with 2 units of insulin, became hypoglycemic (2.51 ± 0.48 m m versus 14.42 ± 0.35 m m )…”
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Interactions of glyceraldehyde-3-phosphate dehydrogenase with G- and F-actin predicted by Brownian dynamics by Ouporov, Igor V., Knull, Harvey R., Lowe, Stephen L., Thomasson, Kathryn A.

“…Brownian dynamics (BD) was used to simulate the binding of glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) to G‐ and F‐actin. High‐resolution…”
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Binding constants and stoichiometries of glyceraldehyde 3-phosphate dehydrogenase-tubulin complexes by Muronetz, V I, Wang, Z X, Keith, T J, Knull, H R, Srivastava, D K

“…The catalytic activity of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) decreased (almost linearly) as a function of increasing concentrations of tubulin;…”
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Association of glycolytic enzymes with the cytoskeleton by Knull, H R, Walsh, J L

“…The diverse physical associations of the glycolytic enzymes with structural components of the cell suggest that the glycolytic enzymes are not entirely soluble…”
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Computer Simulations of Glycolytic Enzyme Interactions with F-actin by Ouporov, Igor V., Keith, Tim J., Knull, Harvey R., Thomasson, Kathryn A.

“…Muscle actin and fructose-1, 6-bisphosphate aldolase (aldolase) were chemically crosslinked to produce an 80 kDa product representing one subunit of aldolase…”
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Effect of tubulin on the activity of the muscle isoenzyme of lactate dehydrogenase by Marmillot, P, Keith, T, Srivastava, D K, Knull, H R

“…The interaction between muscle-type lactate dehydrogenase (LDHm) and tubulin was investigated by monitoring the combined effect of NADH and tubulin on…”
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Glycolytic enzyme-tubulin interactions: role of tubulin carboxy terminals by Volker, K W, Knull, H R

“…Tubulin and microtubules were modified with the protease, subtilisin. The modification reduced the length of alpha- or beta-tubulin by cleaving a peptide…”
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Glycolytic enzyme interactions with tubulin and microtubules by Walsh, J L, Keith, T J, Knull, H R

“…Interactions of the glycolytic enzymes glucose-6-phosphate isomerase, aldolase, glyceraldehyde-3-phosphate dehydrogenase, triose-phosphate isomerase, enolase,…”
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Nonenzymatic incorporation of glucose and galactose into brain cytoskeletal proteins in vitro by Brown, M R, Keith, T J, Knull, H R

“…Initial studies demonstrated the loss of lysine and simultaneous appearance of glucitollysine in intracellular proteins following incubation with sugar. For…”
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Extraction of glycolytic enzymes: myo-inositol as a marker of membrane porosity by Knull, H R

“…Detergent extraction of brain slices and mouse fibroblast 3T3 cells was performed to determine rates and relative amounts of extraction of inositol versus the…”
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Demonstration of tubulin-glycolytic enzyme interactions using a novel electrophoretic approach by Karkhoff-Schweizer, R, Knull, H R

“…A gel electrophoretic technique was used to demonstrate an interaction with the soluble enzymes aldolase, glyceraldehydephosphate dehydrogenase, pyruvate…”
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