Search Results - "Knuesel, I"

Decisive role of Reelin signaling during early stages of Alzheimer’s disease by Krstic, D, Pfister, S, Notter, T, Knuesel, I

“…Highlights • Early Alzheimer’s disease neuropathology affects olfactory–limbic networks. • Reelin-expressing projection neurons are crucial for…”
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Maternal immune activation during pregnancy increases limbic GABAA receptor immunoreactivity in the adult offspring : Implications for schizophrenia by NYFFELER, M, MEYER, U, YEE, B. K, FELDON, J, KNUESEL, I

“…Prenatal exposures to a variety of infections have been associated with an increased incidence of schizophrenia. We have reported that a single injection of…”
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Amphetamine sensitization in rats as an animal model of schizophrenia by Peleg-Raibstein, D., Knuesel, I., Feldon, J.

“…Based on the ‘endogenous dopamine sensitization’ hypothesis of schizophrenia the present study employed a repeated amphetamine administration regime in order…”
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S.01.01 New insights into neural substrates of Alzheimer's disease: a role for the regulator of neuroplasticity, Reelin? by Knuesel, I, Notter, T, Pfister, S, Krstic, D

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Alterations in dystrophin and utrophin expression parallel the reorganization of GABAergic synapses in a mouse model of temporal lobe epilepsy by Knuesel, Irene, Zuellig, Richard A., Schaub, Marcus C., Fritschy, Jean-Marc

“…Dystrophin and its autosomal homologue utrophin are coexpressed in muscle cells, and utrophin is functionally able to replace dystrophin in models of Duchenne…”
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Reduced Reelin Expression Accelerates Amyloid-  Plaque Formation and Tau Pathology in Transgenic Alzheimer's Disease Mice by Kocherhans, S., Madhusudan, A., Doehner, J., Breu, K. S., Nitsch, R. M., Fritschy, J.-M., Knuesel, I.

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P.2.29 Hyperactivity and response to amphetamine in SynGAP heterozygous knockout mice by Muhia, M, Yee, B.K, Feldon, J, Knuesel, I

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Altered human oligodendrocyte heterogeneity in multiple sclerosis by Jäkel, Sarah, Agirre, Eneritz, Mendanha Falcão, Ana, van Bruggen, David, Lee, Ka Wai, Knuesel, Irene, Malhotra, Dheeraj, ffrench-Constant, Charles, Williams, Anna, Castelo-Branco, Gonçalo

“…Oligodendrocyte pathology is increasingly implicated in neurodegenerative diseases as oligodendrocytes both myelinate and provide metabolic support to axons…”
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Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice by Meyer, Urs, Nyffeler, Myriel, Yee, Benjamin K, Knuesel, Irene, Feldon, Joram

“…Abstract Maternal infection during pregnancy increases the risk for neurodevelopmental disorders such as schizophrenia and autism in the offspring. This…”
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Maternal immune activation during pregnancy increases limbic GABA A receptor immunoreactivity in the adult offspring: Implications for schizophrenia by Nyffeler, M., Meyer, U., Yee, B.K., Feldon, J., Knuesel, I.

“…Prenatal exposures to a variety of infections have been associated with an increased incidence of schizophrenia. We have reported that a single injection of…”
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Prenatal infection as driving force of aging-associated neurodegenerative diseases by Knuesel, I

“…Alzheimer's disease (AD) is the most common type of age-related dementia. Besides few genetic mutations, many non-genetic risk factors are known to…”
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Comparative studies of suidatrestin, a specific inhibitor of trehalases by Knuesel, Irène, Murao, Sawao, Shin, Takashi, Amachi, Teruo, Kayser, Hartmut

“…Suidatrestin, isolated from a Streptomyces strain, was characterized as a new trehalase inhibitor. Its inhibitory potential was 7 to 50-fold higher than that…”
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Long-term effects of early life deprivation on brain glia in Fischer rats by Leventopoulos, Michail, Rüedi-Bettschen, Daniela, Knuesel, Irene, Feldon, Joram, Pryce, Christopher R, Opacka-Juffry, Jolanta

“…Abstract Both clinical and experimental studies have indicated that depression and depression-like animal conditions are associated with disruption of the…”
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Primate Early Life Stress Leads to Long-Term Mild Hippocampal Decreases in Corticosteroid Receptor Expression by Arabadzisz, Dimitrula, Diaz-Heijtz, Rochellys, Knuesel, Irene, Weber, Elisabeth, Pilloud, Sonia, Dettling, Andrea C, Feldon, Joram, Law, Amanda J, Harrison, Paul J, Pryce, Christopher R

“…Background Expression of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) genes are moderately reduced in several brain regions in depression…”
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Characterization and Turnover of CD73/IP 3 R3-positive Microvillar Cells in the Adult Mouse Olfactory Epithelium by Pfister, S., Dietrich, M. G., Sidler, C., Fritschy, J.-M., Knuesel, I., Elsaesser, R.

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Single nuclei transcriptomics of human white matter oligodendroglia in multiple sclerosis by Agirre, E, Jakel, S, Falcao, AM, van Bruggen, D, Knuesel, I, Malhotra, D, Lee, KW, Ffrench-Constant, C, Williams, A, Castelo-Branco, G

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Single nuclei transcriptomics of human white matter oligodendroglia in multiple sclerosis by Agirre, E, Jakel, S, Falcao, AM, van Bruggen, D, Lee, KW, Knuesel, I, Malhotra, D, Ffrench-Constant, C, Williams, A, Castelo-Branco, G

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Maternal immune activation during pregnancy increases limbic GABA sub(A) receptor immunoreactivity in the adult offspring: Implications for schizophrenia by Nyffeler, M, Meyer, U, Yee, B K, Feldon, J, Knuesel, I

“…Prenatal exposures to a variety of infections have been associated with an increased incidence of schizophrenia. We have reported that a single injection of…”
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P38 AGE-DEPENDENT PHENOTYPIC CHARACTERISTICS OF A TRIPLE TRANSGENIC MOUSE MODEL OF ALZHEIMER??S DISEASE: EMOTION, ATTENTION AND COGNITION by Pietropaolo, S., Laferla, F.M., Knuesel, I., Feldon, J., Yee, B.K.

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Differential expression of utrophin and dystrophin in CNS neurons: An in situ hybridization and immunohistochemical study by Knuesel, Irene, Bornhauser, Beat C., Zuellig, Richard A., Heller, Franziska, Schaub, Marcus C., Fritschy, Jean-Marc

“…The cellular distribution of utrophin, the autosomal homologue of dystrophin, was investigated in developing and adult rat and mouse brain by in situ…”
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