Search Results - "Knowles, Sonja L."

Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Aspergillus Species by Steenwyk, Jacob L, Mead, Matthew E, Knowles, Sonja L, Raja, Huzefa A, Roberts, Christopher D, Bader, Oliver, Houbraken, Jos, Goldman, Gustavo H, Oberlies, Nicholas H, Rokas, Antonis

“…Abstract Aspergillus fumigatus is a major fungal pathogen of humans but its two closest relatives, Aspergillus fischeri and Aspergillus oerlinghausenensis, are…”
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Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature by Oberlies, Nicholas H, Knowles, Sonja L, Amrine, Chiraz Soumia M, Kao, Diana, Kertesz, Vilmos, Raja, Huzefa A

“…Covering: up to 2019The chemistry of nature can be beautiful, inspiring, beneficial and poisonous, depending on perspective. Since the isolation of the first…”
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Opportunities and Limitations for Assigning Relative Configurations of Antibacterial Bislactones using GIAO NMR Shift Calculations by Knowles, Sonja L, Roberts, Christopher D, Augustinović, Mario, Flores-Bocanegra, Laura, Raja, Huzefa A, Heath-Borrero, Kimberly N, Burdette, Joanna E, Falkinham III, Joseph O, Pearce, Cedric J, Oberlies, Nicholas H

“…Four new bislactones, dihydroacremonol (1), clonostachyone (2), acremodiol B (3), and acremodiol C (4), along with one known compound, hymeglusin (5), were…”
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Mapping the Fungal Battlefield: Using in situ Chemistry and Deletion Mutants to Monitor Interspecific Chemical Interactions Between Fungi by Knowles, Sonja L, Raja, Huzefa A, Wright, Allison J, Lee, Ann Marie L, Caesar, Lindsay K, Cech, Nadja B, Mead, Matthew E, Steenwyk, Jacob L, Ries, Laure N A, Goldman, Gustavo H, Rokas, Antonis, Oberlies, Nicholas H

“…Fungi grow in competitive environments, and to cope, they have evolved strategies, such as the ability to produce a wide range of secondary metabolites. This…”
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Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus by Steenwyk, Jacob L, Mead, Matthew E, de Castro, Patrícia Alves, Valero, Clara, Damasio, André, Dos Santos, Renato A C, Labella, Abigail L, Li, Yuanning, Knowles, Sonja L, Raja, Huzefa A, Oberlies, Nicholas H, Zhou, Xiaofan, Cornely, Oliver A, Fuchs, Frieder, Koehler, Philipp, Goldman, Gustavo H, Rokas, Antonis

“…The ongoing global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for coronavirus disease 2019 (COVID-19),…”
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Genomic and Phenotypic Trait Variation of the Opportunistic Human Pathogen Aspergillus flavus and Its Close Relatives by Hatmaker, E Anne, Rangel-Grimaldo, Manuel, Raja, Huzefa A, Pourhadi, Hadi, Knowles, Sonja L, Fuller, Kevin, Adams, Emily M, Lightfoot, Jorge D, Bastos, Rafael W, Goldman, Gustavo H, Oberlies, Nicholas H, Rokas, Antonis

“…Fungal diseases affect millions of humans annually, yet fungal pathogens remain understudied. The mold Aspergillus flavus can cause both aspergillosis and…”
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Color Protection from UV irradiation of artificial dyes with grape seed (Vitis vinifera) extract by Knowles, Sonja L, Sheng, Wei, Davis, Stephanie, Sica, Vincent P, Pulliam, Christopher J, Baker, Timothy R, Li, Lijuan, Marsh, Jennifer M, Fang, Rui, Padilla-González, Guillermo F, Simmonds, Monique SJ

“…Hair color fade is an important issue for consumers who use permanent hair colorants and is caused by both washing and UV exposure. The mechanism of…”
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Fungal-fungal co-culture: a primer for generating chemical diversity by Knowles, Sonja L, Raja, Huzefa A, Roberts, Christopher D, Oberlies, Nicholas H

“…Covering: 2002 to 2020In their natural environment, fungi must compete for resources. It has been hypothesized that this competition likely induces the…”
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Metabolomics-Guided Comparison of Pollen and Microalgae-Based Artificial Diets in Honey Bees by Ricigliano, Vincent A., Cank, Kristof B., Todd, Daniel A., Knowles, Sonja L., Oberlies, Nicholas H.

“…Managed honey bee colonies used for crop pollination are fed artificial diets to offset nutritional deficiencies related to land-use intensification and…”
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Pathogenic Allodiploid Hybrids of Aspergillus Fungi by Steenwyk, Jacob L., Lind, Abigail L., Ries, Laure N.A., dos Reis, Thaila F., Silva, Lilian P., Almeida, Fausto, Bastos, Rafael W., Fraga da Silva, Thais Fernanda de Campos, Bonato, Vania L.D., Pessoni, André Moreira, Rodrigues, Fernando, Raja, Huzefa A., Knowles, Sonja L., Oberlies, Nicholas H., Lagrou, Katrien, Goldman, Gustavo H., Rokas, Antonis

“…Interspecific hybridization substantially alters genotypes and phenotypes and can give rise to new lineages. Hybrid isolates that differ from their parental…”
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Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri by Knowles, Sonja L, Mead, Matthew E, Silva, Lilian Pereira, Raja, Huzefa A, Steenwyk, Jacob L, Goldman, Gustavo H, Oberlies, Nicholas H, Rokas, Antonis

“…is a major opportunistic human pathogen. Multiple traits contribute to pathogenicity, including its ability to produce specific secondary metabolites, such as…”
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Bioactive diterpenoid metabolism and cytotoxic activities of genetically transformed Euphorbia lathyris roots by Ricigliano, Vincent A., Sica, Vincent P., Knowles, Sonja L., Diette, Nicole, Howarth, Dianella G., Oberlies, Nicholas H.

“…Plants in the genus Euphorbia produce a wide variety of pharmacologically active diterpenoids with anticancer, multidrug resistance reversal, and antiviral…”
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Capturing the antimicrobial profile of Rosmarinus officinalis against methicillin-resistant Staphylococcus aureus (MRSA) with bioassay-guided fractionation and bioinformatics by Khin, Manead, Knowles, Sonja L., Crandall, William J., Jones, Derick D., Oberlies, Nicholas H., Cech, Nadja B., Houriet, Joëlle

“…[Display omitted] •First report of the antimicrobial activity of micromeric acid (1) against MRSA.•Positive correlations of isolated compounds to the…”
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Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS) by Knowles, Sonja L, Vu, Ngoc, Todd, Daniel A, Raja, Huzefa A, Rokas, Antonis, Zhang, Qibin, Oberlies, Nicholas H

“…Most often, the structures of secondary metabolites are solved using a suite of NMR techniques. However, there are times when it can be challenging to position…”
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Wheldone: Characterization of a Unique Scaffold from the Coculture of Aspergillus fischeri and Xylaria flabelliformis by Knowles, Sonja L, Raja, Huzefa A, Isawi, Israa H, Flores-Bocanegra, Laura, Reggio, Patricia H, Pearce, Cedric J, Burdette, Joanna E, Rokas, Antonis, Oberlies, Nicholas H

“…Wheldone (1) was isolated and elucidated from a coculture of Aspergillus fischeri (NRRL 181) and Xylaria flabelliformis (G536), where secondary metabolite…”
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Regulation of gliotoxin biosynthesis and protection in Aspergillus species by de Castro, Patrícia Alves, Colabardini, Ana Cristina, Moraes, Maísa, Horta, Maria Augusta Crivelente, Knowles, Sonja L, Raja, Huzefa A, Oberlies, Nicholas H, Koyama, Yasuji, Ogawa, Masahiro, Gomi, Katsuya, Steenwyk, Jacob L, Rokas, Antonis, Gonçales, Relber A, Duarte-Oliveira, Cláudio, Carvalho, Agostinho, Ries, Laure N A, Goldman, Gustavo H

“…Aspergillus fumigatus causes a range of human and animal diseases collectively known as aspergillosis. A. fumigatus possesses and expresses a range of genetic…”
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Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144) by Cank, Kristóf B., Shepherd, Robert A., Knowles, Sonja L., Rangel-Grimaldo, Manuel, Raja, Huzefa A., Bunch, Zoie L., Cech, Nadja B., Rice, Christopher A., Kyle, Dennis E., Falkinham, Joseph O., Burdette, Joanna E., Oberlies, Nicholas H.

“…Studies on an organic extract of a marine fungus, Periconia sp. (strain G1144), led to the isolation of three halogenated cyclopentenes along with the known…”
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Characterizing the Pathogenic, Genomic, and Chemical Traits of Aspergillus fischeri , a Close Relative of the Major Human Fungal Pathogen Aspergillus fumigatus by Mead, Matthew E, Knowles, Sonja L, Raja, Huzefa A, Beattie, Sarah R, Kowalski, Caitlin H, Steenwyk, Jacob L, Silva, Lilian P, Chiaratto, Jessica, Ries, Laure N A, Goldman, Gustavo H, Cramer, Robert A, Oberlies, Nicholas H, Rokas, Antonis

“…is closely related to , the major cause of invasive mold infections. Even though is commonly found in diverse environments, including hospitals, it rarely…”
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Draft Genome Sequence of the Griseofulvin-Producing Fungus Xylaria flabelliformis Strain G536 by Mead, Matthew E., Raja, Huzefa A., Steenwyk, Jacob L., Knowles, Sonja L., Oberlies, Nicholas H., Rokas, Antonis

“…The draft genome of the ascomycete fungus Xylaria flabelliformis (previously known as Xylaria cubensis ) was sequenced using Illumina paired-end technology…”
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Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence Across Aspergillus Species by Steenwyk, Jacob L, Mead, Matthew E, Knowles, Sonja L, Raja, Huzefa A, Roberts, Christopher D, Bader, Oliver, Houbraken, Jos, Goldman, Gustavo H, Oberlies, Nicholas H, Rokas, Antonis

“…Aspergillus fumigatus is a major fungal pathogen of humans but its two closest relatives, Aspergillus fischeri and Aspergillus oerlinghausenensis, are not…”
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