Search Results - "Knowles, Robert W."

Kinetics of Cell Fusion Induced by a Syncytia-Producing Mutant of Herpes Simplex Virus Type I by Person, S, Knowles, R W, Read, G S, Warner, S C, Bond, V C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Treatment of Recalcitrant Plaque Psoriasis with a Humanized Non-depleting Antibody to CD4 by Bachelez, Hervé, Flageul, Béatrice, Dubertret, Louis, Fraitag, Sylvie, Grossman, Rachel, Brousse, Nicole, Poisson, Dominique, Knowles, Robert W., Wacholtz, Mary C., Haverty, Thomas P., Chatenoud, Lucienne, Bach, Jean-François

“…The presence of activated CD4+T lymphocytes in psoriatic skin plaques suggests an immune-mediated pathogenesis for the disease. Six patients with recalcitrant…”
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Humanized IgG1 and IgG4 anti-CD4 monoclonal antibodies: effects on lymphocytes in the blood, lymph nodes, and renal allografts in cynomolgus monkeys by Mourad, G J, Preffer, F I, Wee, S L, Powelson, J A, Kawai, T, Delmonico, F L, Knowles, R W, Cosimi, A B, Colvin, R B

“…Optimizing therapeutic monoclonal antibody (mAb) depends on the incorporation of the necessary effector functions and the development of hypoantigenic…”
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Nondepleting humanized anti-CD4 monoclonal antibody in patients with refractory rheumatoid arthritis by Moreland, L W, Haverty, T P, Wacholtz, M C, Knowles, R W, Bucy, R P, Heck, Jr, L W, Koopman, W J

“…To investigate the safety, tolerability, pharmacokinetics, and immunologic activity of single intravenous infusions (0.2-10 mg/kg) of Orthoclone OKTcdr4a, a…”
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HUMANIZED IgG1 AND IgG4 ANTI-CD4 MONOCLONAL ANTIBODIES: Effects on Lymphocytes in the Blood, Lymph Nodes, and Renal Allografts in Cynomolgus Monkeys1 by Mourad, Georges J., Preffer, Frederic I., Wee, Siew-Lin, Powelson, John A., Kawai, Tatsuo, Delmonico, Francis L., Knowles, Robert W., Cosimi, A. Benedict, Colvin, Robert B.

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An aberrantDRB4 null gene transcript is found that could encode a novel HLA-DR chain by Sutton, Vivien R., Knowles, Robert W.

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CDR-grafted OKT4A monoclonal antibody in cynomolgus renal allograft recipients by Powelson, J A, Knowles, R W, Delmonico, F L, Kawai, T, Mourad, G, Preffer, F K, Colvin, R B, Cosimi, A B

“…In an attempt to improve therapeutic efficacy and limit antimurine responses to the IgG2a monoclonal antibody OKT4A, humanized complementarity determining…”
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A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin by Knowles, R W, Bodmer, W F

“…A monoclonal antibody, M241, was produced which binds to a human cell surface molecule with properties similar to the murine thymus leukemia (TL) antigen. This…”
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An altered splice site is found in the DRB4 gene that is not expressed in HLA-DR7, Dw11 individuals by SUTTON, V. R, KIENZLE, B. K, KNOWLES, R. W

“…The HLA-DR beta protein, DR beta IV, encoded by the DRB4 gene, is found on class II+ cells of all DR4, DR9, and most DR7 individuals. However, in some DR7…”
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The Origin of ABH Antigens on Human Platelets by Dunstan, Robert A., Simpson, Marcus B., Knowles, Robert W., Rosse, Wendell F.

“…ABH antigens are present on platelets from individuals of the corresponding red cell phenotype, but the extent to which these antigens are intrinsic or…”
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A unique epitope on the CD2 molecule defined by the monoclonal antibody 9-1: epitope-specific modulation of the E-rosette receptor and effects on T-cell functions by Bernard, A, Knowles, R W, Naito, K, Dupont, B, Raynal, B, Tran, H C, Boumsell, L

“…Monoclonal antibody (MoAb) 9-1 shows unique binding properties to CD2 resulting in peculiar epitope specific changes. 9-1 shows competitive binding with MoAb…”
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CELL FUSION AND THE GLYCOPROTEINS OF HERPES SIMPLEX VIRUS by KNOWLES, ROBERT W

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"The Evolution of Modern Land Warfare: Theory and Practice" by Christopher Bellamy (Book Review) by Knowles, Robert W

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Allocytotoxic T cell clones: both Leu 2+3- and Leu 2-3+ T cells recognize class I histocompatibility antigens by Flomenberg, N, Naito, K, Duffy, E, Knowles, R W, Evans, R L, Dupont, B

“…T cell clones were selected which were cytotoxic for human class I major histocompatibility target antigens. Specificity was based on target cell panel studies…”
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Identification of residues involved in polymorphic antibody binding epitopes on HLA-DR molecules by Fu, X T, Yu, W Y, Alber, C, Benson, C, Watts, R, Nordwig, H, Johnson, J P, Knowles, R W, Karr, R W

“…Based on previous studies it was predicted that amino acids 4 or 25 of the DR4 beta 1 and DR7 beta 1 chains are involved in polymorphic antibody binding…”
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A new supertypic HLA class II determinant (PL2) differentially expressed with DR7, DRw11(5), DRw13(w6), DRw14(w6), DR3, and DR2 and biochemically localized to DR7 molecules by Horibe, K, Knowles, R W, Dupont, B

“…A monoclonal antibody, PL2, has been produced that reacts with a new supertypic determinant expressed on the peripheral blood B lymphocytes and B-leukemic…”
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The evolution of modern land warfare - theory and practice by Bellamy, Christopher, Knowles, Robert W

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Two monoclonal antibodies identifying a subset of human peripheral mononuclear cells with natural killer cell activity by Bai, Y, Beverley, P C, Knowles, R W, Bodmer, W F

“…Two monoclonal antibodies (H25 and H366) raised against the cultured T lymphoid cell line HSB-2 were shown to define a subset of peripheral mononuclear cells…”
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Human cutaneous dendritic cells express two glycoproteins T6 and M241 which are biochemically identical to those found on cortical thymocytes by van de Rijn, M, Lerch, P G, Bronstein, B R, Knowles, R W, Bhan, A K, Terhorst, C

“…Monoclonal antibodies anti-T6 and anti-M241 define unique cell populations within different lineages: cortical thymocytes and dendritic cells in the skin. T6…”
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T lymphocyte clones detecting novel supertypic HLA class II allospecificities by Flomenberg, N, Knowles, R W, Williams, D, Horibe, K, Rosenkrantz, K, Dupont, B

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