Search Results - "Knowles, Michelle K."

Phosphatidic Acid Accumulates at Areas of Curvature in Tubulated Lipid Bilayers and Liposomes by Bills, Broderick L, Knowles, Michelle K

“…Phosphatidic acid (PA) is a signaling lipid that is produced enzymatically from phosphatidylcholine (PC), lysophosphatidic acid, or diacylglycerol. Compared to…”
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Membrane curvature based lipid sorting using a nanoparticle patterned substrate by Black, Joshua C, Cheney, Philip P, Campbell, Travis, Knowles, Michelle K

“…Cellular membranes contain a variety of shapes that likely act as motifs for sorting lipids and proteins. To understand the sorting that takes place within…”
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Membrane dynamics are slowed for Alexa594-labeled membrane proteins due to substrate interactions by Weisgerber, Alan W., Knowles, Michelle K.

“…The addition of fluorescent dyes to proteins, lipids and other biological molecules can affect a range of processes such as mobility, molecular interactions,…”
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Biochemically prepared C-reactive protein conformational states differentially affect C1q binding by Moon, Carrie L., Alnaas, Aml A., Cai, Yuheng, Reed, Scott M., Knowles, Michelle K.

“…•The pCRP to mCRP change is measured using several methods sensitive to conformation.•Several chemical treatments yield modified CRP, few lead to a form that…”
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Single Lipid Molecule Dynamics on Supported Lipid Bilayers with Membrane Curvature by Cheney, Philip P, Weisgerber, Alan W, Feuerbach, Alec M, Knowles, Michelle K

“…The plasma membrane is a highly compartmentalized, dynamic material and this organization is essential for a wide variety of cellular processes. Nanoscale…”
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Modelling the effect of tethering on exosome secretion by Otruba, Zdenek, Mahmood, Anarkali, Weisgerber, Alan, Knowles, Michelle K.

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Phospholipase D1 localizes to mobile, docking and fusing secretory vesicles and multivesicular endosomes by Bills, Broderick L., Hulser, Megan, Knowles, Michelle K.

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Phospholipase D1 produces phosphatidic acid at sites of secretory vesicle docking and fusion by Bills, Broderick L, Hulser, Megan L, Knowles, Michelle K

“…Phospholipase D1 (PLD1) activity is essential for the stimulated exocytosis of secretory vesicles where it acts as a lipid-modifying enzyme to produces…”
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Exosome secretion kinetics are controlled by temperature by Mahmood, Anarkali, Otruba, Zdeněk, Weisgerber, Alan W., Palay, Max D., Nguyen, Melodie T., Bills, Broderick L., Knowles, Michelle K.

“…When multivesicular endosomes (MVEs) fuse with the plasma membrane, exosomes are released into the extracellular space where they can affect other cells. The…”
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Polymer mediated layer-by-layer assembly of different shaped gold nanoparticles by Budy, Stephen M., Hamilton, Desmond J., Cai, Yuheng, Knowles, Michelle K., Reed, Scott M.

“…[Display omitted] Gold nanoparticles (GNPs) have a wide range of properties with potential applications in electronics, optics, catalysis, and sensing. In…”
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Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure by Alhalwani, Amani Y., Repine, John E., Knowles, Michelle K., Huffman, J. Alex

“…Lactoferrin (LF) is an important multifunctional protein that comprises a large fraction of the protein mass in certain human fluids and tissues, and its…”
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Cytoskeletal-Assisted Dynamics of the Mitochondrial Reticulum in Living Cells by Knowles, Michelle K., Guenza, Marina G., Capaldi, Roderick A., Marcus, Andrew H.

“…Subcellular organelle dynamics are strongly influenced by interactions with cytoskeletal filaments and their associated motor proteins, and lead to complex…”
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Conformational Changes in C‑Reactive Protein Affect Binding to Curved Membranes in a Lipid Bilayer Model of the Apoptotic Cell Surface by Alnaas, Aml A, Moon, Carrie L, Alton, Mitchell, Reed, Scott M, Knowles, Michelle K

“…C-reactive protein (CRP) is a serum protein that binds to damaged membranes through a phosphatidylcholine binding site. The membrane binding process can…”
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Fluorescence quantum yield measurements of fluorescent proteins: A laboratory experiment for a biochemistry or molecular biophysics laboratory course by Wall, Kathryn P., Dillon, Rebecca, Knowles, Michelle K.

“…Fluorescent proteins are commonly used in cell biology to assess where proteins are within a cell as a function of time and provide insight into intracellular…”
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C-reactive protein (CRP) aptamer binds to monomeric but not pentameric form of CRP by Wang, Min S., Black, Joshua C., Knowles, Michelle K., Reed, Scott M.

“…Native C-reactive protein (CRP) is composed of five identical subunits arranged in a pentameric structure (pCRP). Binding of pCRP to damaged cell membranes…”
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Quantification of phosphatidic acid sorting in curved membranes using tubulated bilayers by Bills, Broderick L., Knowles, Michelle K.

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A Membrane Tubule Bilayer Assay for Curvature Sorting of Phosphatidic Acid by Bills, Broderick L., Knowles, Michelle K.

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Direct measurement of relative and collective diffusion in a dilute binary colloidal suspension by Knowles, Michelle K, Honerkamp-Smith, Aurelia R, Marcus, Andrew H

“…Experimental characterization of the dynamics of multicomponent fluids is a problem of general importance to the field of complex fluids. We demonstrate a new…”
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Dynamics of Syntaxin at sites of constitutive and stimulated fusion by Weisgerber, Alan W., Nguyen, Melodie, Mahmood, Anarkali, Palay, Max, Otruba, Zdenek, Knowles, Michelle K.

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Exosome secretion kinetics are controlled by tethering and temperature by Mahmood, Anarkali, Weisgerber, Alan, Otruba, Zdenek, Palay, Max, Knowles, Michelle K.

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