Search Results - "Knowles, BB"

A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo by Do, Dang Vinh, Ueda, Jun, Messerschmidt, Daniel M, Lorthongpanich, Chanchao, Zhou, Yi, Feng, Bo, Guo, Guoji, Lin, Peiyu J, Hossain, Md Zakir, Zhang, Wenjun, Moh, Akira, Wu, Qiang, Robson, Paul, Ng, Huck Hui, Poellinger, Lorenz, Knowles, Barbara B, Solter, Davor, Fu, Xin-Yuan

“…Although it is known that OCT4-NANOG are required for maintenance of pluripotent cells in vitro, the upstream signals that regulate this circuit during early…”
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Retrotransposons Regulate Host Genes in Mouse Oocytes and Preimplantation Embryos by Peaston, Anne E., Evsikov, Alexei V., Graber, Joel H., de Vries, Wilhelmine N., Holbrook, Andrea E., Solter, Davor, Knowles, Barbara B.

“…A comprehensive analysis of transposable element (TE) expression in mammalian full-grown oocytes reveals that LTR class III retrotransposons make an…”
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The$G_{s}-Linked$Receptor GPR3 Maintains Meiotic Arrest in Mammalian Oocytes by Mehlmann, Lisa M., Saeki, Yoshinaga, Tanaka, Shigeru, Brennan, Thomas J., Evsikov, Alexei V., Pendola, Frank L., Knowles, Barbara B., Eppig, John J., Jaffe, Laurinda A.

“…Mammalian oocytes are held in prophase arrest by an unknown signal from the surrounding somatic cells. Here we show that the orphan$G_{s}-linked$receptor GPR3,…”
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Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells by Akopian, Veronika, Andrews, Peter W, Beil, Stephen, Benvenisty, Nissim, Brehm, Jennifer, Christie, Megan, Ford, Angela, Fox, Victoria, Gokhale, Paul J, Healy, Lyn, Holm, Frida, Hovatta, Outi, Knowles, Barbara B, Ludwig, Tenneille E, McKay, Ronald D. G, Miyazaki, Takamichi, Nakatsuji, Norio, Oh, Steve K. W, Pera, Martin F, Rossant, Janet, Stacey, Glyn N, Suemori, Hirofumi

“…There are many reports of defined culture systems for the propagation of human embryonic stem cells in the absence of feeder cell support, but no previous…”
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Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast by Kemler, Rolf, Hierholzer, Andreas, Kanzler, Benoît, Kuppig, Stefan, Hansen, Kati, Taketo, Makoto M, de Vries, Wilhelmine N, Knowles, Barbara B, Solter, Davor

“…Many components of the Wnt/beta-catenin signaling pathway are expressed during mouse pre-implantation embryo development, suggesting that this pathway may…”
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Timely translation during the mouse oocyte-to-embryo transition by Oh, B, Hwang, S, McLaughlin, J, Solter, D, Knowles, B B

“…In the mouse, completion of oocyte maturation and the initiation of preimplantation development occur during transcriptional silence and depend on the presence…”
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The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein by Ackerman, Susan L, Kozak, Leslie P, Przyborski, Stefan A, Rund, Laurie A, Boyer, Bert B, Knowles, Barbara B

“…Migration of neurons from proliferative zones to their functional sites is fundamental to the normal development of the central nervous system. Mice homozygous…”
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Systems biology of the 2-cell mouse embryo by Evsikov, A V, de Vries, W N, Peaston, A E, Radford, E E, Fancher, K S, Chen, F H, Blake, J A, Bult, C J, Latham, K E, Solter, D, Knowles, B B

“…The transcriptome of the 2-cell mouse embryo was analyzed to provide insight into the molecular networks at play during nuclear reprogramming and embryonic…”
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Genome function and nuclear architecture: from gene expression to nanoscience by O'Brien, Timothy P, Bult, Carol J, Cremer, Christoph, Grunze, Michael, Knowles, Barbara B, Langowski, Jorg, McNally, James, Pederson, Thoru, Politz, Joan C, Pombo, Ana, Schmahl, Gunter, Spatz, Joachim P, van Driel, Roel

“…Biophysical, chemical, and nanoscience approaches to the study of nuclear structure and activity have been developing recently and hold considerable promise. A…”
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Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary by Przyborski, S A, Knowles, B B, Ackerman, S L

“…Mutation of the Unc5h3 (formally known as rcm) gene has important consequences on neuronal migration during cerebellar development. Unc5h3 transcripts are…”
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Spindlin, a major maternal transcript expressed in the mouse during the transition from oocyte to embryo by Oh, B, Hwang, S Y, Solter, D, Knowles, B B

“…Timely translation of maternal transcripts and post-translational modification of their gene products control the initial development of preimplantation-stage…”
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Molecular control of the oocyte to embryo transition by Knowles, Barbara B., Evsikov, Alexei V., de Vries, Wilhelmine N., Peaston, Anne E., Solter, Davor

“…The elucidation of the molecular control of the initiation of mammalian embryogenesis is possible now that the transcriptomes of the full–grown oocyte and…”
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Proteotypic classification of spontaneous and transgenic mammary neoplasms by Mikaelian, Igor, Blades, Natalie, Churchill, Gary A, Fancher, Karen, Knowles, Barbara B, Eppig, Janan T, Sundberg, John P

“…Mammary tumors in mice are categorized by using morphologic and architectural criteria. Immunolabeling for terminal differentiation markers was compared among…”
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Abnormalities of chromosome 1 and loss of heterozygosity on 1p in primary hepatomas by Simon, D, Knowles, B B, Weith, A

“…Cytogenetic analysis of eight human hepatoma-derived cell lines and one primary hepatocellular carcinoma biopsy revealed multiple chromosome abnormalities;…”
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New member of the Snf1/AMPK kinase family, Melk, is expressed in the mouse egg and preimplantation embryo by Heyer, Babette S., Warsowe, Jennie, Solter, Davor, Knowles, Barbara B., Ackerman, Susan L.

“…The initial phase of mammalian preimplantation development is directed by stored maternal mRNAs and their encoded proteins, yet most of the molecules…”
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Sequential loss of cytotoxic T lymphocyte responses to simian virus 40 large T antigen epitopes in T antigen transgenic mice developing osteosarcomas by SCHELL, T. D, KNOWLES, B. B, TEVETHIA, S. S

“…The role of CTL tolerance in tumor immunity to SV40 large T antigen (T ag)-induced tumors was studied using T ag transgenic mice of the line 501 (H2b). 501…”
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Expression and cell membrane localization of catenins during mouse preimplantation development by Ohsugi, Mami, Hwang, Sue‐Yun, Butz, Stefan, Knowles, Barbara B., Solter, Davor, Kemler, Rolf

“…We have studied transcription, expression, and membrane localization of components of the E‐cadherin‐catenin complex stage by stage during mouse…”
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Epigenetic mechanisms in early mammalian development by Solter, D, Hiiragi, T, Evsikov, A V, Moyer, J, De Vries, W N, Peaston, A E, Knowles, B B

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Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23 by ACKERMAN, S. L, KNOWLES, B. B

“…The vertebrate Unc5 genes, like their Caenorhabditis elegans counterpart, define a family of putative netrin receptors. One member of this family, Unc5h3, has…”
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Immune Effector Mechanisms Required for Protection to Rabies Virus by XIANG, Z.Q., KNOWLES, B.B., McCARRICK, J.W., ERTL, H.C.J.

“…Genetically engineered mice with targeted mutations in genes encoding immunologically relevant molecules were used to elucidate the role of different immune…”
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