Search Results - "Knott, G. W"

Neuron Segmentation With High-Level Biological Priors by Krasowski, N. E., Beier, T., Knott, G. W., Kothe, U., Hamprecht, F. A., Kreshuk, A.

“…We present a novel approach to the problem of neuron segmentation in image volumes acquired by an electron microscopy. Existing methods, such as agglomerative…”
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Development of Walking, Swimming and Neuronal Connections after Complete Spinal Cord Transection in the Neonatal Opossum, Monodelphis domestica by Saunders, N. R, Kitchener, P, Knott, G. W, Nicholls, J. G, Potter, A, Smith, T. J

“…Development of coordinated movements was quantitatively assessed in adult opossums (Monodelphis domestica) with thoracic spinal cords transected by (1)…”
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Synapse formation in adult barrel cortex following naturalistic environmental enrichment by Landers, M.S, Knott, G.W, Lipp, H.P, Poletaeva, I, Welker, E

“…Abstract Environmental enrichment paradigms in adult laboratory animals, consisting of physical, perceptual, and social stimulation, have been shown to affect…”
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Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex by Svoboda, Karel, Trachtenberg, Joshua T, Chen, Brian E, Knott, Graham W, Feng, Guoping, Sanes, Joshua R, Welker, Egbert

“…Do new synapses form in the adult cortex to support experience-dependent plasticity? To address this question, we repeatedly imaged individual pyramidal…”
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Imaging of experience-dependent structural plasticity in the mouse neocortex in vivo by Holtmaat, A., De Paola, V., Wilbrecht, L., Knott, G.W.

“…The functionality of adult neocortical circuits can be altered by novel experiences or learning. This functional plasticity appears to rely on changes in the…”
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Albumin transfer across the choroid plexus of South American opossum (Monodelphis domestica) by Knott, G W, Dziegielewska, K M, Habgood, M D, Li, Z S, Saunders, N R

“…1. Blood-cerebrospinal fluid (CSF) transfer of various exogenous albumins has been investigated in developing Monodelphis domestica (South American grey…”
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The nature of the decrease in blood-cerebrospinal fluid barrier exchange during postnatal brain development in the rat by Habgood, M D, Knott, G W, Dziegielewska, K M, Saunders, N R

“…1. The blood-cerebrospinal fluid (CSF) exchange of a wide range of passively transported lipid insoluble compounds (0.43-5.4 nm molecular radius) has been…”
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Improving 3D EM data segmentation by joint optimization over boundary evidence and biological priors by Krasowski, N., Beier, T., Knott, G. W., Koethe, U., Hamprecht, F. A., Kreshuk, A.

“…We present a new automated neuron segmentation algorithm for isotropic 3D electron microscopy data. We cast the problem into the asymmetric multiway cut…”
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Altered Synapse Formation in the Adult Somatosensory Cortex of Brain-Derived Neurotrophic Factor Heterozygote Mice by Genoud, Christel, Knott, Graham W, Sakata, Kazuko, Lu, Bai, Welker, Egbert

“…Increased sensory stimulation in the adult whisker-to-barrel pathway induces the expression of BDNF as well as synapse formation in cortical layer IV. Here, we…”
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PERMEABILITY OF THE DEVELOPING AND MATURE BLOOD-BRAIN BARRIERS TO THEOPHYLLINE IN RATS by Habgood, MD, Knott, GW, Dziegielewska, KM, Saunders, NR

“…SUMMARY 1. In the present study, the uptake of theophylline and L‐glucose into the adult and neonatal rat brain has been investigated. Steady state…”
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Development of connections by axons growing through injured spinal cord of neonatal opossum in culture by WOODWARD, S. K. A, TREHERNE, J. M, KNOTT, G. W, FERNANDEZ, J, VARGA, Z. M, NICHOLLS, J. G

“…The ability of neurites to grow through a lesion and form synaptic connections has been analyzed in a developing mammalian spinal cord in vitro. After…”
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Repair and recovery following spinal cord injury in a neonatal marsupial (Monodelphis domestica) by Saunders, N R, Deal, A, Knott, G W, Varga, Z M, Nicholls, J G

“…1. Repair and recovery following spinal cord injury (complete spinal cord crush) has been studied in vitro in neonatal opossum (Monodelphis domestica), fetal…”
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Barriers in the immature brain by Saunders, N R, Knott, G W, Dziegielewska, K M

“…1. The term "blood-brain barrier" describes a range of mechanisms that control the exchange of molecules between the internal environment of the brain and the…”
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TGF-beta receptor type II and fetuin in the developing sheep neocortex by Dziegielewska, K M, Williams, R T, Knott, G W, Kitchener, P D, Monk, S E, Potter, A, Saunders, N R

“…Fetuin shows a characteristic pattern of distribution in the developing neocortex in many mammalian species. Its expression is confined to early-appearing…”
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Fetuin expression in the dorsal root ganglia and trigeminal ganglia of perinatal rats by Kitchener, P.D., Dziegielewska, K.M., Knott, G.W., Miller, J.M., Nawratil, P., Potter, A.E., Saunders, N.R.

“…Fetuin, a fetal plasma glycoprotein, has been shown previously to be present in sub‐populations of neurons in the developing central and peripheral nervous…”
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Development of thalamocortical projections in the South American gray short-tailed opossum (Monodelphis domestica) by Molnár, Zoltán, Knott, Graham W., Blakemore, Colin, Saunders, Norman R.

“…We determined the time‐course and general pattern of thalamocortical development of Monodelphis domestica by tracing projections with carbocyanine dye in fixed…”
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Formation of Dendritic Spines with GABAergic Synapses Induced by Whisker Stimulation in Adult Mice by Knott, Graham W., Quairiaux, Charles, Genoud, Christel, Welker, Egbert

“…During development, alterations in sensory experience modify the structure of cortical neurons, particularly at the level of the dendritic spine. Are similar…”
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The nature and composition of the internal environment of the developing brain by Dziegielewska, K M, Knott, G W, Saunders, N R

“…1. The fetal brain develops within its own environment, which is protected from free exchange of most molecules among its extracellular fluid, blood plasma,…”
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Delayed and Temporally Imprecise Neurotransmission in Reorganizing Cortical Microcircuits by Barnes, Samuel J, Cheetham, Claire E, Liu, Yan, Bennett, Sophie H, Albieri, Giorgia, Jorstad, Anne A, Knott, Graham W, Finnerty, Gerald T

“…Synaptic neurotransmission is modified at cortical connections throughout life. Varying the amplitude of the postsynaptic response is one mechanism that…”
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Development of motoneurons and primary sensory afferents in the thoracic and lumbar spinal cord of the South American opossum Monodelphis domestica by Knott, Graham W., Kitchener, Peter D., Saunders, Norman R.

“…The postnatal development of the primary sensory afferent projection to the thoracic (T4) and lumbar (L4) spinal cord of the marsupial species Monodelphis…”
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