Search Results - "Knops, Elena"

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents by Kalaghatgi, Prabhav, Sikorski, Anna Maria, Knops, Elena, Rupp, Daniel, Sierra, Saleta, Heger, Eva, Neumann-Fraune, Maria, Beggel, Bastian, Walker, Andreas, Timm, Jörg, Walter, Hauke, Obermeier, Martin, Kaiser, Rolf, Bartenschlager, Ralf, Lengauer, Thomas

“…The face of hepatitis C virus (HCV) therapy is changing dramatically. Direct-acting antiviral agents (DAAs) specifically targeting HCV proteins have been…”
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HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice by Horwitz, Joshua A., Halper-Stromberg, Ariel, Mouquet, Hugo, Gitlin, Alexander D., Tretiakova, Anna, Eisenreich, Thomas R., Malbec, Marine, Gravemann, Sophia, Billerbeck, Eva, Dorner, Marcus, Büning, Hildegard, Schwartz, Olivier, Knops, Elena, Kaiser, Rolf, Seaman, Michael S., Wilson, James M., Rice, Charles M., Ploss, Alexander, Bjorkman, Pamela J., Klein, Florian, Nussenzweig, Michel C.

“…Effective control of HIV-1 infection in humans is achieved using combinations of antiretroviral therapy (ART) drugs. In humanized mice (hu-mice), control of…”
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RNAemia Corresponds to Disease Severity and Antibody Response in Hospitalized COVID-19 Patients by Eberhardt, Kirsten Alexandra, Meyer-Schwickerath, Charlotte, Heger, Eva, Knops, Elena, Lehmann, Clara, Rybniker, Jan, Schommers, Philipp, Eichenauer, Dennis A, Kurth, Florian, Ramharter, Michael, Kaiser, Rolf, Holtick, Udo, Klein, Florian, Jung, Norma, Di Cristanziano, Veronica

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a global health emergency. To improve the understanding of the systemic component of…”
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Optimizing Antiretroviral Therapy in Heavily ART-Experienced Patients with Multi-Class Resistant HIV-1 Using Proviral DNA Genotypic Resistance Testing by Rauschning, Dominic, Ehren, Ira, Heger, Eva, Knops, Elena, Fätkenheuer, Gerd, Suárez, Isabelle, Lehmann, Clara

“…Resistance to multiple antiretroviral drugs among people living with HIV (PLWH) can result in a high pill burden, causing toxicity and drug interactions. Thus,…”
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Detection and characterization of enteroviruses and parechoviruses in healthy people living in the South of Côte d’Ivoire by Cristanziano, Veronica Di, Böttcher, Sindy, Diedrich, Sabine, Timmen-Wego, Monika, Knops, Elena, Lübke, Nadine, Kaiser, Rolf, Pfister, Herbert, Kaboré, Yolande, D'Alfonso, Rossella

“…Highlights • EVs and HPeVs infecting healthy people in Côte d’Ivoire were characterized. • EV serotypes belonging to EV group A–C were identified. • Rarely…”
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Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana by Di Cristanziano, Veronica, D'Alfonso, Rossella, Berrilli, Federica, Sarfo, Fred Stephen, Santoro, Maristella, Fabeni, Lavinia, Knops, Elena, Heger, Eva, Kaiser, Rolf, Dompreh, Albert, Phillips, Richard Odame, Norman, Betty, Feldt, Torsten, Eberhardt, Kirsten Alexandra

“…Sub-Saharan Africa is endemic for intestinal parasites and distinguished for the largest burden of HIV cases. Blastocystis sp. is one of the most common…”
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Drug Resistance Spread in 6 Metropolitan Regions, Germany, 2001-2018 by Stecher, Melanie, Chaillon, Antoine, Stephan, Christoph, Knops, Elena, Kohmer, Niko, Lehmann, Clara, Eberle, Josef, Bogner, Johannes, Spinner, Christoph D, Eis-Hubinger, Anna Maria, Wasmuth, Jan-Christian, Schafer, Guido, Behrens, Georg, Mehta, Sanjay R, Vehreschild, Jorg Janne, Hoenigl, Martin

“…We analyzed 1,397 HIV-1 pol sequences of antiretroviral therapy–naive patients in a total of 7 university hospitals in Bonn, Cologne, Frankfurt, Hamburg,…”
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Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana by Di Cristanziano, Veronica, D Alfonso, Rossella, Berrilli, Federica, Sarfo, Fred Stephen, Santoro, Maristella, Fabeni, Lavinia, Knops, Elena, Heger, Eva, Kaiser, Rolf, Dompreh, Albert, Phillips, Richard Odame, Norman, Betty, Feldt, Torsten, Eberhardt, Kirsten Alexandra

“…[This corrects the article DOI: 10.1371/journal.pone.0221968.]…”
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HIV-1 Sub-Subtype A6: Settings for Normalised Identification and Molecular Epidemiology in the Southern Federal District, Russia by Schlösser, Madita, Kartashev, Vladimir V, Mikkola, Visa H, Shemshura, Andrey, Saukhat, Sergey, Kolpakov, Dmitriy, Suladze, Alexandr, Tverdokhlebova, Tatiana, Hutt, Katharina, Heger, Eva, Knops, Elena, Böhm, Michael, Di Cristanziano, Veronica, Kaiser, Rolf, Sönnerborg, Anders, Zazzi, Maurizio, Bobkova, Marina, Sierra, Saleta

“…Russia has one of the largest and fastest growing HIV epidemics. However, epidemiological data are scarce. Sub-subtype A6 is most prevalent in Russia but its…”
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From Gut to Blood: Redistribution of Zonulin in People Living with HIV by Augustin, Max, Horn, Carola, Ercanoglu, Meryem Seda, Bondet, Vincent, de Silva, Ute Sandaradura, Suarez, Isabelle, Chon, Seung-Hun, Nierhoff, Dirk, Zoufaly, Alexander, Wenisch, Christoph, Knops, Elena, Heger, Eva, Klein, Florian, Duffy, Darragh, Müller-Trutwin, Michaela, Lehmann, Clara

“…Gastrointestinal mucosal damage due to human immunodeficiency virus (HIV) infection leads to microbial translocation and immune activation, contributing to the…”
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Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana by Di Cristanziano, Veronica, Weimer, Kristina, Böttcher, Sindy, Sarfo, Fred Stephen, Dompreh, Albert, Cesar, Lucio-Garcia, Knops, Elena, Heger, Eva, Wirtz, Maike, Kaiser, Rolf, Norman, Betty, Phillips, Richard Odame, Feldt, Torsten, Eberhardt, Kirsten Alexandra

“…In the post-polio eradication era, increasing attention is given to non-polio enteroviruses. Most of the data about enteroviruses in sub-Saharan Africa are…”
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Combined Therapy with Intravenous Immunoglobulins, Letermovir and (Val-)Ganciclovir in Complicated Courses of CMV-Infection in Transplant Recipients by Di Cristanziano, Veronica, Affeldt, Patrick, Trappe, Moritz, Wirtz, Maike, Heger, Eva, Knops, Elena, Kaiser, Rolf, Stippel, Dirk, Müller, Roman-Ulrich, Holtick, Udo, Scheid, Christoph, Kann, Martin, Kurschat, Christine E., Grundmann, Franziska

“…The treatment options for cytomegalovirus (CMV) infections in immunosuppressed patients are limited, mainly consisting of (val-)ganciclovir (VGC/GCV) as the…”
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CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue by Augustin, Max, Horn, Carola, Ercanoglu, Meryem Seda, Sandaradura de Silva, Ute, Bondet, Vincent, Suarez, Isabelle, Chon, Seung-Hun, Nierhoff, Dirk, Knops, Elena, Heger, Eva, Vivaldi, Carlo, Schäfer, Hartmut, Oette, Mark, Fätkenheuer, Gerd, Klein, Florian, Duffy, Darragh, Müller-Trutwin, Michaela, Lehmann, Clara

“…(1) Background: The gut-associated lymphatic tissue (GALT) represents the largest lymphoid organ, and is considered to be the largest HIV reservoir. The exact…”
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High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates by VERHEYEN, Jens, VERHOFSTEDE, Chris, NIJHUIS, Monique, KNOPS, Elena, VANDEKERCKHOVE, Linos, FUN, Axel, BRUNEN, Diede, DAUWE, Kenny, WENSING, Annemarie M. J, PFISTER, Herbert, KAISER, Rolf

“…Bevirimat is the first drug of a new class of antivirals that hamper the maturation of HIV. The objective of this study was to evaluate the sequence…”
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CMV-IgG pre-allogeneic hematopoietic stem cell transplantation and the risk for CMV reactivation and mortality by Eberhardt, Kirsten Alexandra, Jung, Verena, Knops, Elena, Heger, Eva, Wirtz, Maike, Steger, Gertrud, Kaiser, Rolf, Affeldt, Patrick, Holtick, Udo, Klein, Florian, Scheid, Christof, Di Cristanziano, Veronica

“…Cytomegalovirus (CMV) represents one of the most common infectious complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT)…”
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geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data by Döring, Matthias, Büch, Joachim, Friedrich, Georg, Pironti, Alejandro, Kalaghatgi, Prabhav, Knops, Elena, Heger, Eva, Obermeier, Martin, Däumer, Martin, Thielen, Alexander, Kaiser, Rolf, Lengauer, Thomas, Pfeifer, Nico

“…Abstract Identifying resistance to antiretroviral drugs is crucial for ensuring the successful treatment of patients infected with viruses such as human…”
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Detection of SARS-CoV-2 viremia before onset of COVID-19 symptoms in an allo-transplanted patient with acute leukemia by Di Cristanziano, Veronica, Meyer-Schwickerath, Charlotte, Eberhardt, Kirsten Alexandra, Rybniker, Jan, Heger, Eva, Knops, Elena, Hallek, Michael, Klein, Florian, Holtick, Udo, Jung, Norma

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Analysis of antibodies from HCV elite neutralizers identifies genetic determinants of broad neutralization by Weber, Timm, Potthoff, Julian, Bizu, Sven, Labuhn, Maurice, Dold, Leona, Schoofs, Till, Horning, Marcel, Ercanoglu, Meryem S., Kreer, Christoph, Gieselmann, Lutz, Vanshylla, Kanika, Langhans, Bettina, Janicki, Hanna, Ströh, Luisa J., Knops, Elena, Nierhoff, Dirk, Spengler, Ulrich, Kaiser, Rolf, Bjorkman, Pamela J., Krey, Thomas, Bankwitz, Dorothea, Pfeifer, Nico, Pietschmann, Thomas, Flyak, Andrew I., Klein, Florian

“…The high genetic diversity of hepatitis C virus (HCV) complicates effective vaccine development. We screened a cohort of 435 HCV-infected individuals and found…”
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Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R by Lübke, Nadine, Jensen, Björn, Hüttig, Falk, Feldt, Torsten, Walker, Andreas, Thielen, Alexander, Däumer, Martin, Obermeier, Martin, Kaiser, Rolf, Knops, Elena, Heger, Eva, Sierra, Saleta, Oette, Mark, Lengauer, Thomas, Timm, Jörg, Häussinger, Dieter

“…In this case report, the emergence of HIV-1 resistance to dolutegravir is identified early after the initiation of antiretroviral treatment…”
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Torque teno virus‐DNA load as individual cytomegalovirus risk assessment parameter upon allogeneic hematopoietic stem cell transplantation by Spiertz, Arlene, Tsakmaklis, Anastasia, Farowski, Fedja, Knops, Elena, Heger, Eva, Wirtz, Maike, Kaiser, Rolf, Holtick, Udo, Vehreschild, Maria J. G. T., Di Cristanziano, Veronica

“…Abstract Background Immune recovery following allogeneic hematopoietic stem cell transplantation (allo‐HSCT) decisively influences the occurrence of…”
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