Search Results - "Knopp, Kristeene"
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Zika virus cell tropism in the developing human brain and inhibition by azithromycin
Published in Proceedings of the National Academy of Sciences - PNAS (13-12-2016)“…The rapid spread of Zika virus (ZIKV) and its association with abnormal brain development constitute a global health emergency. Congenital ZIKV infection…”
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Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens
Published in Genome medicine (25-08-2016)“…Ocular infections remain a major cause of blindness and morbidity worldwide. While prognosis is dependent on the timing and accuracy of diagnosis, the etiology…”
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3
Zika virus alters centrosome organization to suppress the innate immune response
Published in EMBO reports (05-09-2022)“…Zika virus (ZIKV) is a flavivirus transmitted via mosquitoes and sex to cause congenital neurodevelopmental defects, including microcephaly. Inherited forms of…”
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Genome-Wide Knockout Screen Identifies Human Sialomucin CD164 as an Essential Entry Factor for Lymphocytic Choriomeningitis Virus
Published in mBio (28-06-2022)“…Lymphocytic choriomeningitis virus (LCMV) is a well-studied mammarenavirus that can be fatal in congenital infections. However, our understanding of LCMV and…”
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LCMV glycosylation modulates viral fitness and cell tropism
Published in PloS one (07-01-2013)“…The glycoprotein (GP) of arenaviruses is glycosylated at 11 conserved N-glycosylation sites. We constructed recombinant lymphocytic choriomeningitis virus…”
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A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D
Published in Toxins (10-09-2021)“…Human botulism can be caused by botulinum neurotoxin (BoNT) serotypes A to G. Here, we present an antibody-based antitoxin composed of four human monoclonal…”
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Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system
Published in Laboratory investigation (01-02-2014)“…Coxsackievirus B3 (CVB3) and lymphocytic choriomeningitis virus (LCMV) are both neurotropic RNA viruses, which can establish a persistent infection and cause…”
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Single nucleoprotein residue modulates arenavirus replication complex formation
Published in mBio (28-04-2015)“…The Arenaviridae are enveloped, negative-sense RNA viruses with several family members that cause hemorrhagic fevers. This work provides immunofluorescence…”
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Glycosylation modulates arenavirus glycoprotein expression and function
Published in Virology (New York, N.Y.) (20-01-2011)“…Abstract The glycoprotein of lymphocytic choriomeningitis virus (LCMV) contains nine potential N-linked glycosylation sites. We investigated the function of…”
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Erratum to: Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens
Published in Genome medicine (22-11-2016)“…It has come to our attention that there is an error in Fig. 3a for this article [1]. The correct version of Fig. 3a can be found below. The red markers now…”
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Using Phage Display to Select Antibodies Recognizing Post-translational Modifications Independently of Sequence Context
Published in Molecular & cellular proteomics (01-12-2006)“…Many cellular activities are controlled by post-translational modifications, the study of which is hampered by the lack of specific reagents due in large part…”
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Intranasal parainfluenza virus type 5 (PIV5)-vectored RSV vaccine is safe and immunogenic in healthy adults in a phase 1 clinical study
Published in Science advances (27-10-2023)“…Respiratory syncytial virus (RSV) can lead to serious disease in infants, and no approved RSV vaccine is available for infants. This first in-human clinical…”
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Tissue‐Selective Effects of Injected Deoxycholate
Published in Dermatologic surgery (01-06-2010)“…BACKGROUND Recent studies suggest that the principal active ingredient in phosphatidylcholine‐containing injectable fat‐reduction formulations is actually…”
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Dissecting the Multiple Functions of the Lymphocytic Choriomeningitis Virus Nucleoprotein
Published 01-01-2015“…The Arenaviridae are enveloped, negative-sense RNA viruses with several family members that cause hemorrhagic fevers. These viruses encode only four open…”
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Dissertation -
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Phage Wrapping with Cationic Polymers Eliminates Non-specific Binding between M13 Phage and High pI Target Proteins
Published in Journal of the American Chemical Society (18-11-2009)“…M13 phage have provided scaffolds for nanostructure synthesis based upon self-assembled inorganic and hard materials interacting with phage-displayed peptides…”
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Phage Wrapping with Cationic Polymers Eliminates Nonspecific Binding between M13 Phage and High p I Target Proteins
Published in Journal of the American Chemical Society (18-11-2009)Get full text
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Phage Wrapping with Cationic Polymers Eliminates Nonspecific Binding between M13 Phage and High pI Target Proteins
Published in Journal of the American Chemical Society (18-11-2009)“…M13 phage have provided scaffolds for nanostructure synthesis based upon self-assembled inorganic and hard materials interacting with phage-displayed peptides…”
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Journal Article