Search Results - "Knoll, Laura"

Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction by Martorelli Di Genova, Bruno, Wilson, Sarah K, Dubey, J P, Knoll, Laura J

“…Many eukaryotic microbes have complex life cycles that include both sexual and asexual phases with strict species specificity. Whereas the asexual cycle of the…”
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Long-Term Relationships: the Complicated Interplay between the Host and the Developmental Stages of Toxoplasma gondii during Acute and Chronic Infections by Pittman, Kelly J, Knoll, Laura J

“…Toxoplasma gondii represents one of the most common parasitic infections in the world. The asexual cycle can occur within any warm-blooded animal, but the…”
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Entamoeba histolytica: Five facts about modeling a complex human disease in rodents by Mendoza Cavazos, Carolina, Knoll, Laura J

“…Because the cyst stage of E. histolytica cannot be induced in culture or rodents, Entamoeba invadens has served as an excellent model for the study of…”
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Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection by Pittman, Kelly J, Aliota, Matthew T, Knoll, Laura J

“…The obligate intracellular parasite Toxoplasma gondii establishes a life-long chronic infection within any warm-blooded host. After ingestion of an encysted…”
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Parasite microbiome project: Grand challenges by Dheilly, Nolwenn M, Martínez Martínez, Joaquín, Rosario, Karyna, Brindley, Paul J, Fichorova, Raina N, Kaye, Jonathan Z, Kohl, Kevin D, Knoll, Laura J, Lukeš, Julius, Perkins, Susan L, Poulin, Robert, Schriml, Lynn, Thompson, Luke R

“…About the Authors: Nolwenn M. Dheilly * E-mail: nolwenn.dheilly@stonybrook.edu (NMD); jmartinez@bigelow.org (JMM) Affiliation: School of Marine and Atmospheric…”
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Dual metabolomic profiling uncovers Toxoplasma manipulation of the host metabolome and the discovery of a novel parasite metabolic capability by Olson, William J, Martorelli Di Genova, Bruno, Gallego-Lopez, Gina, Dawson, Anthony R, Stevenson, David, Amador-Noguez, Daniel, Knoll, Laura J

“…The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key metabolites and must scavenge these from the host. It is unclear how T…”
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Sex in a dish: high-efficiency Toxoplasma pre-sexual development by Hryckowian, Nicole D., Knoll, Laura J.

“…Antunes et al. successfully grew cat-restricted stages of Toxoplasma gondii in cell culture by targeting parasite epigenetics and transcription factors. The…”
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Breakthroughs in microbiology made possible with organoids by Ramírez-Flores, Carlos J, Knoll, Laura J

“…Organoids are cultured from stem cells and form three-dimensional (3D) structures that mimic the organ, including multiple cell types, protein expression, and…”
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Development of Complex Models to Study Co- and Polymicrobial Infections and Diseases by Rall, Glenn, Knoll, Laura J

“…Glenn Rall * E-mail: glenn.rall@fccc.edu (GR); ljknoll@wisc.edu (LJK) Affiliation: Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of…”
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Proteomic and transcriptomic analyses of early and late-chronic Toxoplasma gondii infection shows novel and stage specific transcripts by Garfoot, Andrew L, Wilson, Gary M, Coon, Joshua J, Knoll, Laura J

“…The protozoan pathogen Toxoplasma gondii has the unique ability to develop a chronic infection in the brain of its host by transitioning from the fast growing…”
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Patatin‐like phospholipases in microbial infections with emerging roles in fatty acid metabolism and immune regulation by Apicomplexa by Wilson, Sarah K., Knoll, Laura J.

“…Summary Emerging lipidomic technologies have enabled researchers to dissect the complex roles of phospholipases in lipid metabolism, cellular signaling and…”
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Transcriptional Analysis Shows a Robust Host Response to Toxoplasma gondii during Early and Late Chronic Infection in Both Male and Female Mice by Garfoot, Andrew L, Cervantes, Patrick W, Knoll, Laura J

“…The long-term host effects caused by the protozoan parasite are poorly understood. High-throughput RNA sequencing analysis previously determined that the host…”
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Investigating the role of interleukin 10 on Eimeria intestinal pathogenesis in broiler chickens by Arendt, Maria, Elissa, Jonathan, Schmidt, Natalie, Michael, Emily, Potter, Nicole, Cook, Mark, Knoll, Laura J.

“…•Intestinal cytokine responses differ by section during a mixed Eimeria infection.•Duodenal intestinal epithelial cell IL-10 and IFNγ increase during Eimeria…”
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A Toxoplasma gondii patatin-like phospholipase contributes to host cell invasion by Wilson, Sarah K, Heckendorn, Justine, Martorelli Di Genova, Bruno, Koch, Lindsey L, Rooney, Peggy J, Morrissette, Naomi, Lebrun, Maryse, Knoll, Laura J

“…Toxoplasma gondii is an obligate intracellular parasite that can invade any nucleated cell of any warm-blooded animal. In a previous screen to identify…”
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Comparisons of the Sexual Cycles for the Coccidian Parasites Eimeria and Toxoplasma by Martorelli Di Genova, Bruno, Knoll, Laura J

“…and spp. are widely prevalent Coccidian parasites that undergo sexual reproduction during their life cycle. can infect any warm-blooded animal in its asexual…”
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Editorial overview of Pearls Microbiome Series: E pluribus unum by Hogan, Deborah A, Heitman, Joseph, Jabra-Rizk, Mary Ann, Knoll, Laura J, Leong, John M, Silverman, Neal

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RIPK3 Facilitates Host Resistance to Oral Toxoplasma gondii Infection by Cervantes, Patrick W, Martorelli Di Genova, Bruno, Erazo Flores, Billy Joel, Knoll, Laura J

“…infection activates pattern recognition receptor (PRR) pathways that drive innate inflammatory responses to control infection. Necroptosis is a proinflammatory…”
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Emergence of Constructor-Based Irreversibility in Quantum Systems: Theory and Experiment by Marletto, Chiara, Vedral, Vlatko, Knoll, Laura T, Piacentini, Fabrizio, Bernardi, Ettore, Rebufello, Enrico, Avella, Alessio, Gramegna, Marco, Degiovanni, Ivo Pietro, Genovese, Marco

“…How irreversibility arises in a universe with time-reversal symmetric laws is a central problem in physics. In this Letter, we discuss a radically different…”
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Using Entamoeba muris To Model Fecal-Oral Transmission of Entamoeba in Mice by Mendoza Cavazos, Carolina, Heredia, Marienela Y, Owens, Leah A, Knoll, Laura J

“…There are several species that colonize humans, but only Entamoeba histolytica causes severe disease. E. histolytica is transmitted through the fecal-oral…”
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VESPA: an optimized protocol for accurate metabarcoding-based characterization of vertebrate eukaryotic endosymbiont and parasite assemblages by Owens, Leah A., Friant, Sagan, Martorelli Di Genova, Bruno, Knoll, Laura J., Contreras, Monica, Noya-Alarcon, Oscar, Dominguez-Bello, Maria G., Goldberg, Tony L.

“…Protocols for characterizing taxonomic assemblages by deep sequencing of short DNA barcode regions (metabarcoding) have revolutionized our understanding of…”
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