Search Results - "Knoll, Andrea"
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PNA FIT-Probes for the Dual Color Imaging of Two Viral mRNA Targets in Influenza H1N1 Infected Live Cells
Published in Bioconjugate chemistry (17-10-2012)“…Fluorogenic hybridization probes that allow RNA imaging provide information as to how the synthesis and transport of particular RNA molecules is orchestrated…”
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2
Prevalence of coat colour traits and congenital disorders of South American camelids in Austria, Germany and Switzerland
Published in Acta veterinaria scandinavica (18-09-2020)“…The increasing popularity of alpacas and llamas outside of South America is undeniable. The associated limited genetic diversity raises questions about health…”
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3
Remote Control of Lipophilic Nucleic Acids Domain Partitioning by DNA Hybridization and Enzymatic Cleavage
Published in Journal of the American Chemical Society (19-12-2012)“…Lateral partitioning of lipid-modified molecules between liquid-disordered (ld) and liquid-ordered (lo) domains depends on the type of lipid modification,…”
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4
Synthesis and Functional Studies of a Membrane-Bound THF-Gramicidin Cation Channel
Published in Angewandte Chemie International Edition (03-03-2000)“…Synthetic THF – gramicidin hybrids incorporated in membranes form cation‐selective ion channels. These were evident from the measurement of single channel…”
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5
Double FIT hybridization probes - towards enhancing brightness, turn-on and specificity of RNA detection
Published in Chemical science (Cambridge) (12-04-2023)“…Efficient fluorogenic hybridization probes combine high brightness and specificity of fluorescence signaling with large turn-on of fluorescence. Herein, we…”
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Dual fluorophore PNA FIT-probes--extremely responsive and bright hybridization probes for the sensitive detection of DNA and RNA
Published in Organic & biomolecular chemistry (28-09-2012)“…Fluorescently labeled oligonucleotides are commonly employed as probes to detect specific DNA or RNA sequences in homogeneous solution. Useful probes should…”
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7
Chemo-biological mRNA imaging with single nucleotide specificity
Published in Chemical communications (Cambridge, England) (05-12-2019)“…Unambiguous imaging of C → U edited mRNA calls for a method that distinguishes a locally high concentration of unbound probe or single nucleotide mismatched…”
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Fluorescence Imaging of Influenza H1N1 mRNA in Living Infected Cells Using Single-Chromophore FIT-PNA
Published in Angewandte Chemie (International ed.) (18-02-2011)“…A message from the virus was detected by a peptide nucleic acid probe that contains thiazole orange as a fluorescent base surrogate (see picture). The high…”
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9
Comparing Agent‐Based Delivery of DNA and PNA Forced Intercalation (FIT) Probes for Multicolor mRNA Imaging
Published in Chembiochem : a European journal of chemical biology (15-02-2019)“…Fluorogenic oligonucleotide probes allow mRNA imaging in living cells. A key challenge is the cellular delivery of probes. Most delivery agents, such as…”
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10
FIT probes: Peptide nucleic acid probes with a fluorescent base surrogate enable real-time DNA quantification and single nucleotide polymorphism discovery
Published in Analytical biochemistry (15-04-2008)“…The ability to accurately quantify specific nucleic acid molecules in complex biomolecule solutions in real time is important in diagnostic and basic research…”
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Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes
Published in Journal of perinatology (01-04-2020)“…Objective To determine the associations between age at first postnatal corticosteroids (PNS) exposure and risk for severe bronchopulmonary dysplasia (BPD) and…”
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12
Cortisol awakening response and developmental outcomes at 6–7 years in children born extremely preterm
Published in Pediatric research (01-02-2023)“…Background Extremely preterm (EPT) birth has been related to dysregulation of stress responses and behavioral/learning problems at school age. Early adverse…”
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13
Stammlose PNA‐Beacons für die empfindliche DNA‐ und RNA‐Detektion mit geringem Hintergrundrauschen
Published in Angewandte Chemie (24-11-2008)“…Ein Wechsel des Energietransfermechanismus (von Kontaktlöschen zu FRET) steigert die Empfindlichkeit fluoreszenzmarkierter Hybridisierungssonden…”
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14
Low-Noise Stemless PNA Beacons for Sensitive DNA and RNA Detection
Published in Angewandte Chemie (International ed.) (24-11-2008)“…A change of the energy transfer mechanism (from contact quenching to FRET) increases the responsiveness of fluorescent hybridization probes. The communication…”
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15
Relocation Issues in Child Custody Evaluations: A Survey of Professionals
Published in Family court review (01-07-2016)“…We report on a sample of 90 child custody evaluators in the United States, who completed an online questionnaire on their attitudes and beliefs in child…”
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Fluorescence Imaging of Influenza Virus H1N1 mRNA in Living Infected Cells using Single Chromophore FIT-PNA
Published in Biophysical journal (01-02-2011)Get full text
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17
Use of the combination of the BRIEF and basc-2 in assessment of ADHD
Published 01-01-2013“…ADHD is one of the most frequently diagnosed childhood disorders in the United States today; however, diagnostic specificity remains challenging. Accepted…”
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Dissertation -
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Synthesis and functional studies of THF-gramicidin hybrid ion channels
Published in Organic & biomolecular chemistry (21-08-2003)“…THF-gramicidin hybrids 2-4 with the L-THF amino acid 1 in positions 11 and 12 and compounds 5-8 with the D-THF amino acid ent-1 in positions 10 and 11 were…”
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Journal Article -
19
Cyclohexylether δ-Amino Acids: New Leads for Selectivity Filters in Ion Channels
Published in Angewandte Chemie International Edition (01-06-2001)“…Synthetic ion channels containing δ‐amino acids can become cation selective! δ‐Amino acids with a cyclohexylether unit (see structure) were combined with…”
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20
Tetrahydropyran-Amino Acids: Novel Building Blocks for Gramicidin-Hybrid Ion Channels
Published in European Journal of Organic Chemistry (01-06-2006)“…The stereoselective synthesis of a cis‐2,6‐disubstituted tetrahydropyran bearing a δ‐amino acid has been achieved starting from N‐Boc‐leucinal. The THP amino…”
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