Search Results - "Knochel, Paul"

Recent Advances of the Halogen–Zinc Exchange Reaction by Balkenhohl, Moritz, Knochel, Paul

“…For the preparation of zinc organometallics bearing highly sensitive functional groups such as ketones, aldehydes or nitro groups, especially mild halogen–zinc…”
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Improving the Halogen–Magnesium Exchange by using New Turbo‐Grignard Reagents by Ziegler, Dorothée S., Wei, Baosheng, Knochel, Paul

“…This Minireview describes the scope of the halogen–magnesium exchange. It shows that the use of the turbo‐Grignard reagent (iPrMgCl⋅LiCl) greatly enhances the…”
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Highly Regioselective Addition of Allylic Zinc Halides and Various Zinc Enolates to [1.1.1]Propellane by Schwärzer, Kuno, Zipse, Hendrik, Karaghiosoff, Konstantin, Knochel, Paul

“…We report a range of highly regioselective openings of [1.1.1]propellane with various allylic zinc halides, as well as zinc enolates of ketones, esters and…”
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Regio- and Chemoselective Metalation of Arenes and Heteroarenes Using Hindered Metal Amide Bases by Haag, Benjamin, Mosrin, Marc, Ila, Hiriyakkanavar, Malakhov, Vladimir, Knochel, Paul

“…The preparation of highly functionalized organometallic compounds can be achieved by direct CH activation of a broad range of unsaturated substrates using…”
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Transition-Metal-Free BF3‑Mediated Regioselective Direct Alkylation and Arylation of Functionalized Pyridines Using Grignard or Organozinc Reagents by Chen, Quan, du Jourdin, Xavier Mollat, Knochel, Paul

“…A formal regioselective cross-coupling of various pyridines with alkyl and aryl groups can be achieved by a BF3·OEt2-mediated addition of Grignard or…”
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TMPZnCl·LiCl: A New Active Selective Base for the Directed Zincation of Sensitive Aromatics and Heteroaromatics by Mosrin, Marc, Knochel, Paul

“…A wide range of polyfunctional aryl and heteroaryl zinc reagents were efficiently prepared in THF via direct zincation using TMPZnCl·LiCl, a new exceptionally…”
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Sodiation of Arenes and Heteroarenes in Continuous Flow by Weidmann, Niels, Ketels, Marthe, Knochel, Paul

“…The first sodiations of (hetero)arenes in continuous flow using NaDA (sodium diisopropylamide) in Me2EtN are reported. This flow procedure enables sodiation of…”
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Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para‐Disubstituted Benzenes from [1.1.1]Propellane by Makarov, Ilya S., Brocklehurst, Cara E., Karaghiosoff, Konstantin, Koch, Guido, Knochel, Paul

“…We report a general preparation of arylated bicyclo[1.1.1]pentanes through the opening of [1.1.1]propellane with various arylmagnesium halides. After…”
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Iron‐Mediated Electrophilic Amination of Organozinc Halides using Organic Azides by Graßl, Simon, Singer, Johannes, Knochel, Paul

“…A wide range of alkyl‐, aryl‐ and heteroarylzinc halides were aminated with highly functionalized alkyl, aryl, and heterocyclic azides. The reaction proceeds…”
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Radical Catalysis of Kumada Cross-Coupling Reactions Using Functionalized Grignard Reagents by Manolikakes, Georg, Knochel, Paul

“…Palladium, radically different: A wide range of polyfunctional aryl‐ and heteroarylmagnesium reagents undergo fast Kumada cross‐couplings (see scheme) with…”
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A Photoconductive Thienothiophene-Based Covalent Organic Framework Showing Charge Transfer Towards Included Fullerene by Dogru, Mirjam, Handloser, Matthias, Auras, Florian, Kunz, Thomas, Medina, Dana, Hartschuh, Achim, Knochel, Paul, Bein, Thomas

“…Filling a honeycomb: The thienothiophene‐based covalent organic framework (COF) can be loaded with a complementary semiconductor, such as a fullerene…”
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Practical Continuous-Flow Trapping Metalations of Functionalized Arenes and Heteroarenes Using TMPLi in the Presence of Mg, Zn, Cu, or La Halides by Becker, Matthias R., Knochel, Paul

“…The flow metalation of various arenes and heteroarenes involving an in situ trapping with metal salts (ZnCl2⋅2 LiCl, MgCl2, CuCN⋅2 LiCl, LaCl3⋅2 LiCl) under…”
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Synthesis of Functionalized Benzo[b]thiophenes by the Intramolecular Copper-Catalyzed Carbomagnesiation of Alkynyl(aryl)thioethers by Kunz, Thomas, Knochel, Paul

“…Highly functional: A copper(I)‐catalyzed intramolecular carbomagnesiation under mild conditions transforms readily available alkynyl(aryl)thioethers into…”
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Synthesis of Functionalized Diaryl Sulfides by Cobalt-Catalyzed Coupling between Arylzinc Pivalates and Diaryl Disulfides by Dong, Zhi-Bing, Balkenhohl, Moritz, Tan, Eric, Knochel, Paul

“…An efficient protocol for the cobalt-catalyzed preparation of diaryl sulfides from solid organozinc pivalates and commercially available diaryl disulfides is…”
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Preparation of Functionalized Indoles and Azaindoles by the Intramolecular Copper-Mediated Carbomagnesiation of Ynamides by Frischmuth, Annette, Knochel, Paul

“…Variations on a theme: A mild and general intramolecular copper‐mediated carbomagnesiation procedure for the synthesis of functionalized indoles as well as 4‐,…”
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Mixed Mg/Li Amides of the Type R2NMgCl⋅LiCl as Highly Efficient Bases for the Regioselective Generation of Functionalized Aryl and Heteroaryl Magnesium Compounds by Krasovskiy, Arkady, Krasovskaya, Valeria, Knochel, Paul

“…Two are better than one: Mixed lithium‐magnesium complexes of the type R2NMgCl⋅LiCl are kinetically highly active bases that convert a range of polyfunctional…”
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Strategies To Prepare and Use Functionalized Organometallic Reagents by Klatt, Thomas, Markiewicz, John T, Sämann, Christoph, Knochel, Paul

“…Polyfunctional zinc and magnesium organometallic reagents occupy a central position in organic synthesis. Most organic functional groups are tolerated by zinc…”
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Continuous Flow Preparation of Benzylic Sodium Organometallics by Harenberg, Johannes H., Reddy Annapureddy, Rajasekar, Karaghiosoff, Konstantin, Knochel, Paul

“…We report a lateral sodiation of alkyl(hetero)arenes using on‐demand generated hexane‐soluble (2‐ethylhexyl)sodium (1) in the presence of TMEDA…”
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A LiCl-Mediated Br/Mg Exchange Reaction for the Preparation of Functionalized Aryl- and Heteroarylmagnesium Compounds from Organic Bromides by Krasovskiy, Arkady, Knochel, Paul

“…A wide range of aryl and heteroaryl bromides, which are usually sluggish in exchange reactions, are readily converted into the corresponding Grignard reagents…”
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Room Temperature Synthesis of Covalent–Organic Framework Films through Vapor-Assisted Conversion by Medina, Dana D, Rotter, Julian M, Hu, Yinghong, Dogru, Mirjam, Werner, Veronika, Auras, Florian, Markiewicz, John T, Knochel, Paul, Bein, Thomas

“…We describe the facile synthesis of several two-dimensional covalent–organic frameworks (2D COFs) as films by vapor-assisted conversion at room temperature…”
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