Search Results - "Knobloch, Jürgen"

Biomarkers for Comorbidities Modulate the Activity of T-Cells in COPD by Jamal Jameel, Kaschin, Gallert, Willem-Jakob, Yanik, Sarah D., Panek, Susanne, Kronsbein, Juliane, Jungck, David, Koch, Andrea, Knobloch, Jürgen

“…In smoking-induced chronic obstructive pulmonary disease (COPD), various comorbidities are linked to systemic inflammation and infection-induced exacerbations…”
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Olfactory receptors impact pathophysiological processes of lung diseases in bronchial epithelial cells by Weidinger, Daniel, Jacobsen, Julian, Alisch, Desiree, Uebner, Hendrik, Heinen, Natalie, Greune, Lea, Westhoven, Saskia, Jamal Jameel, Kaschin, Kronsbein, Juliane, Pfaender, Stephanie, Taube, Christian, Reuter, Sebastian, Peters, Marcus, Hatt, Hanns, Knobloch, Jürgen

“…Therapeutic options for steroid-resistant non-type 2 inflammation in obstructive lung diseases are limited. Bronchial epithelial cells are key in the…”
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Shedding light on an old mystery: Thalidomide suppresses survival pathways to induce limb defects by Knobloch, Jürgen, Rüther, Ulrich

“…Many hypotheses have been proposed to explain the molecular mechanism of thalidomide teratogenicity, in particular regarding to limb defects. Most experimental…”
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Long-Term Cryopreservation of Nasal Polyp Tissue in a Biobank for the Isolation and Culture of Primary Epithelial Cells by Kim, Jonghui, Hegener, Karla, Hagedorn, Claudia, Jamal Jameel, Kaschin, Weidinger, Daniel, Seuthe, Inga Marte Charlott, Eichhorn, Sabine, Kreppel, Florian, Knobloch, Jürgen, Park, Jonas Jae-Hyun

“…Epithelial cells may play an important role in the pathologic process of chronic rhinosinusitis with nasal polyps. Therefore, providing epithelial cells from a…”
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OR2AT4 and OR1A2 counterregulate molecular pathophysiological processes of steroid-resistant inflammatory lung diseases in human alveolar macrophages by Weidinger, Daniel, Jamal Jameel, Kaschin, Alisch, Desiree, Jacobsen, Julian, Bürger, Paul, Ruhe, Matthias, Yusuf, Faisal, Rohde, Simon, Störtkuhl, Klemens, Kaufmann, Peter, Kronsbein, Juliane, Peters, Marcus, Hatt, Hanns, Giannakis, Nikolaos, Knobloch, Jürgen

“…Therapeutic options for steroid-resistant non-type 2 inflammation in obstructive lung diseases are lacking. Alveolar macrophages are central in the progression…”
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Quantitative Secretome Analysis of Activated Jurkat Cells Using Click Chemistry-Based Enrichment of Secreted Glycoproteins by Witzke, Kathrin E, Rosowski, Kristin, Müller, Christian, Ahrens, Maike, Eisenacher, Martin, Megger, Dominik A, Knobloch, Jürgen, Koch, Andrea, Bracht, Thilo, Sitek, Barbara

“…Quantitative secretome analyses are a high-performance tool for the discovery of physiological and pathophysiological changes in cellular processes. However,…”
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Olfactory Receptors Modulate Physiological Processes in Human Airway Smooth Muscle Cells by Kalbe, Benjamin, Knobloch, Jürgen, Schulz, Viola M, Wecker, Christine, Schlimm, Marian, Scholz, Paul, Jansen, Fabian, Stoelben, Erich, Philippou, Stathis, Hecker, Erich, Lübbert, Hermann, Koch, Andrea, Hatt, Hanns, Osterloh, Sabrina

“…Pathophysiological mechanisms in human airway smooth muscle cells (HASMCs) significantly contribute to the progression of chronic inflammatory airway diseases…”
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The regulation of Dkk1 expression during embryonic development by Lieven, Oliver, Knobloch, Jürgen, Rüther, Ulrich

“…During embryogenesis, the Dkk1 mediated Wnt inhibition controls the spatiotemporal dynamics of cell fate determination, cell differentiation and cell death…”
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Thalidomide Induces Limb Anomalies by PTEN Stabilization, Akt Suppression, and Stimulation of Caspase-Dependent Cell Death by Knobloch, Juergen, Schmitz, Ingo, Goetz, Katrin, Schulze-Osthoff, Klaus, Ruether, Ulrich

“…Errata ( vol. 32 , p. 1757 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Simple, low-cost, and well-performing method, the outgrowth technique, for the isolation of cells from nasal polyps by Kim, Jonghui, Hegener, Karla, Hagedorn, Claudia, Weidinger, Daniel, Jamal Jameel, Kashin, Seuthe, Inga Marte Charlott, Eichhorn, Sabine, Kreppel, Florian, Park, Jonas Jae-Hyun, Knobloch, Jürgen

“…Abstract Background Epithelial cells are an important part of the pathomechanism in chronic rhinosinusitis with nasal polyps. It is therefore essential to…”
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Evaluation of Two Nested PCR Assays for Detection of Histoplasma capsulatum DNA in Human Tissue by BIALEK, Ralf, FEUCHT, Antje, AEPINUS, Christian, JUST-NÜBLING, Gudrun, ROBERTSON, Valerie J, KNOBLOCH, Jürgen, HOHLE, Rolf

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Thalidomide Resistance Is Based on the Capacity of the Glutathione-Dependent Antioxidant Defense by Knobloch, Jürgen, Reimann, Kerstin, Klotz, Lars-Oliver, Rüther, Ulrich

“…Thalidomide as an effective treatment for multiple myeloma and leprosy has also caused birth defects in thousands of children five decades ago particularly in…”
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The formin-homology protein SmDia interacts with the Src kinase SmTK and the GTPase SmRho1 in the gonads of Schistosoma mansoni by Quack, Thomas, Knobloch, Jürgen, Beckmann, Svenja, Vicogne, Jérome, Dissous, Colette, Grevelding, Christoph G

“…Schistosomiasis (bilharzia) is a parasitic disease of worldwide significance affecting human and animals. As schistosome eggs are responsible for pathogenesis,…”
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Isolas of 2-Pulse Solutions in Homoclinic Snaking Scenarios by Knobloch, Jürgen, Lloyd, David J. B., Sandstede, Björn, Wagenknecht, Thomas

“…Homoclinic snaking refers to the bifurcation structure of symmetric localised roll patterns that are often found to lie on two sinusoidal “snaking” bifurcation…”
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Multiple homoclinic orbits in conservative and reversible systems by Homburg, Ale Jan, Knobloch, Jürgen

“…We study dynamics near multiple homoclinic orbits to saddles in conservative and reversible flows. We consider the existence of two homoclinic orbits in the…”
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Detection of Paracoccidioides brasiliensis in Tissue Samples by a Nested PCR Assay by BIALEK, R, IBRICEVIC, A, AEPINUS, C, NAJVAR, L. K, FOTHERGILL, A. W, KNOBLOCH, J, GRAYBILL, J. R

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Cracks in the shell--zooming in on eggshell formation in the human parasite Schistosoma mansoni by Ebersberger, Ingo, Knobloch, Jürgen, Kunz, Werner

“…Schistosomiasis, currently the second most common parasitic disease of humans in tropical regions is caused by the eggs of trematode worms of the genus…”
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Diagnosis and Monitoring of Murine Histoplasmosis by a Nested PCR Assay by BIALEK, Ralf, FISCHER, Jörg, FEUCHT, Antje, NAJVAR, Laura K, DIETZ, Klaus, KNOBLOCH, Jürgen, GRAYBILL, John R

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Resveratrol Attenuates the Release of Inflammatory Cytokines from Human Bronchial Smooth Muscle Cells Exposed to Lipoteichoic Acid in Chronic Obstructive Pulmonary Disease by Knobloch, Jürgen, Wahl, Chiara, Feldmann, Maria, Jungck, David, Strauch, Justus, Stoelben, Erich, Koch, Andrea

“…During bacterial infections, pathogen‐associated molecular patterns (PAMPs) induce cytokine/chemokine release in immunoactive cells. This increases…”
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The monocyte-dependent immune response to bacteria is suppressed in smoking-induced COPD by Knobloch, Jürgen, Panek, Susanne, Yanik, Sarah Derya, Jamal Jameel, Kaschin, Bendella, Zeynep, Jungck, David, Bürger, Paul, Bülthoff, Eike, Struck, Birte, Giannakis, Nikolaos, Rupp, Jan, Kronsbein, Juliane, Peters, Marcus, Koch, Andrea

“…COPD patients have an increased susceptibility to bacterial airway infections that can induce exacerbations. In response to infections, circulating monocytes…”
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