Search Results - "Knobbe, Tim"

A Joint Pharmacokinetic Model for the Simultaneous Description of Plasma and Whole Blood Tacrolimus Concentrations in Kidney and Lung Transplant Recipients by Koomen, Jeroen V., Knobbe, Tim J., Zijp, Tanja R., Kremer, Daan, Gan, C. Tji, Verschuuren, Erik A. M., Bakker, Stephan J. L., Touw, Daan J., Colin, Pieter J.

“…Background and Objective Historically, dosing of tacrolimus is guided by therapeutic drug monitoring (TDM) of the whole blood concentration, which is strongly…”
Get full text

Kidney Transplantation Improves Health-Related Quality of Life in Older Recipients by de Boer, Silke E, Knobbe, Tim J, Kremer, Daan, van Munster, Barbara C, Nieuwenhuijs-Moeke, Gertrude J, Pol, Robert A, Bakker, Stephan J L, Berger, Stefan P, Sanders, Jan Stephan F

“…Kidney transplantation is the best treatment for kidney failure in older patients. However, little is known regarding changes in health-related quality of life…”
Get full text

Effect of vitamin K supplementation on serum calcification propensity and arterial stiffness in vitamin K-deficient kidney transplant recipients: A double-blind, randomized, placebo-controlled clinical trial by Eelderink, Coby, Kremer, Daan, Riphagen, Ineke J., Knobbe, Tim J., Schurgers, Leon J., Pasch, Andreas, Mulder, D.J., Corpeleijn, Eva, Navis, Gerjan, Bakker, Stephan.J.L., de Borst, Martin H., te Velde-Keyzer, Charlotte A.

“…Vitamin K deficiency is common among kidney transplant recipients (KTRs) and likely contributes to progressive vascular calcification and stiffness. In this…”
Get full text

Plasma endotrophin, reflecting tissue fibrosis, is associated with graft failure and mortality in KTRs: results from two prospective cohort studies by Kremer, Daan, Alkaff, Firas F, Post, Adrian, Knobbe, Tim J, Tepel, Martin, Thaunat, Olivier, Berger, Stefan P, van den Born, Jacob, Genovese, Federica, Karsdal, Morten A, Rasmussen, Daniel G K, Bakker, Stephan J L

“…ABSTRACT Background Fibrosis is a suggested cause of graft failure and mortality among kidney transplant recipients (KTRs). Accumulating evidence suggests that…”
Get full text

Low selenium intake is associated with risk of all-cause mortality in kidney transplant recipients by Yepes-Calderón, Manuela, Kremer, Daan, Post, Adrian, Sotomayor, Camilo G, Seidel, Ulrike, Huebbe, Patricia, Knobbe, Tim J, Lüersen, Kai, Eisenga, Michele F, Corpeleijn, Eva, de Borst, Martin H, Navis, Gerjan J, Rimbach, Gerald, Bakker, Stephan J L

“…ABSTRACT Background Deficiency of the essential trace element selenium is common in kidney transplant recipients (KTR), potentially hampering antioxidant and…”
Get full text

Expeditious quantification of plasma tacrolimus with liquid chromatography tandem mass spectrometry in solid organ transplantation by Zijp, Tanja R, Knobbe, Tim J, van Hateren, Kai, Roggeveld, Jan, Blokzijl, Hans, Tji Gan, C, JL Bakker, Stephan, Jongedijk, Erwin M, Investigators, TransplantLines, Touw, Daan J

“…•Report on LC-MS/MS method for quantitation of tacrolimus in plasma.•The method was validated following EMA and FDA guidelines.•Bioanalytical challenges are…”
Get full text

Tremor after solid organ transplantation: Results from the TransplantLines Biobank and Cohort Study by Stouwe, A. Madelein M., Riemersma, Niels L., Knobbe, Tim J., Kremer, Daan, Nolte, Svea, Plasmeijer, Danieke B., Gomes‐Neto, Antonio. W., Bakker, Stephan J. L., Drost, Gea, Elting, Jan Willem J.

“…Background and purpose Tremor is a frequent complaint of solid organ transplant recipients. We report on the largest population investigated with clinical…”
Get full text

Employment Status and Work Functioning among Kidney Transplant Recipients by Knobbe, Tim J, Kremer, Daan, Abma, Femke I, Annema, Coby, Berger, Stefan P, Navis, Gerjan J, van der Mei, Sijrike F, Bültmann, Ute, Visser, Annemieke, Bakker, Stephan J L

“…To date, employment figures of kidney transplant recipients in Europe are inconsistent. Additionally, little is known about work functioning of employed kidney…”
Get full text

Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation by Swarte, J Casper, Li, Yanni, Hu, Shixian, Björk, Johannes R, Gacesa, Ranko, Vich Vila, Arnau, Douwes, Rianne M, Collij, Valerie, Kurilshikov, Alexander, Post, Adrian, Klaassen, Marjolein A Y, Eisenga, Michele F, Gomes-Neto, António W, Kremer, Daan, Jansen, Bernadien H, Knobbe, Tim J, Berger, Stefan P, Sanders, Jan-Stephan F, Heiner-Fokkema, M Rebecca, Porte, Robert J, Cuperus, Frans J C, de Meijer, Vincent E, Wijmenga, Cisca, Festen, Eleonora A M, Zhernakova, Alexandra, Fu, Jingyuan, Harmsen, Hermie J M, Blokzijl, Hans, Bakker, Stephan J L, Weersma, Rinse K

“…Organ transplantation is a life-saving treatment for patients with end-stage disease, but survival rates after transplantation vary considerably. There is now…”
Get more information

Vitamin C deficiency after kidney transplantation: a cohort and cross-sectional study of the TransplantLines biobank by Yepes-Calderón, Manuela, van der Veen, Yvonne, Martín del Campo S, Fernando, Kremer, Daan, Sotomayor, Camilo G., Knobbe, Tim J., Vos, Michel J., Corpeleijn, Eva, de Borst, Martin H., Bakker, Stephan J. L.

“…Purpose Vitamin C deficiency is associated with excess mortality in kidney transplant recipients (KTR). We aim to evaluate plasma vitamin C status at different…”
Get full text

Creatine homeostasis and the kidney: comparison between kidney transplant recipients and healthy controls by Post, Adrian, Groothof, Dion, Kremer, Daan, Knobbe, Tim J., Abma, Willem, Koops, Christa A., Tsikas, Dimitrios, Wallimann, Theo, Dullaart, Robin P.F., Franssen, Casper F.M., Kema, Ido P., Heiner-Fokkema, M. Rebecca, Bakker, Stephan J.L.

“…Creatine is a natural nitrogenous organic acid that is integral to energy metabolism and crucial for proper cell functioning. The kidneys are involved in the…”
Get full text

Rationale and design of TransplantLines: a prospective cohort study and biobank of solid organ transplant recipients by Eisenga, Michele F, Gomes-Neto, Antonio W, van Londen, Marco, Ziengs, Aaltje L, Douwes, Rianne M, Stam, Suzanne P, Osté, Maryse C J, Knobbe, Tim J, Hessels, Niek R, Buunk, Anne M, Annema, Coby, Siebelink, Marion J, Racz, Emoke, Spikman, Jacoba M, Bodewes, Frank A J A, Pol, Robert A, Berger, Stefan P, Drost, Gea, Porte, Robert J, Leuvenink, Henri G D, Damman, Kevin, Verschuuren, Erik A M, de Meijer, Vincent E, Blokzijl, Hans, Bakker, Stephan J L

“…IntroductionIn the past decades, short-term results after solid organ transplantation have markedly improved. Disappointingly, this has not been accompanied by…”
Get full text

Airflow Limitation, Fatigue, and Health-Related Quality of Life in Kidney Transplant Recipients by Knobbe, Tim J, Kremer, Daan, Eisenga, Michele F, van Londen, Marco, Gomes-Neto, António W, Douwes, Rianne M, Gan, C Tji, Corpeleijn, Eva, Annema, Coby, Navis, Gerjan, Berger, Stefan P, Bakker, Stephan J L

“…Many kidney transplant recipients suffer from fatigue and poor health-related quality of life. Airflow limitation may be an underappreciated comorbidity among…”
Get full text

Tremor, Daily Functioning, and Health-Related Quality of Life in Solid Organ Transplant Recipients by Riemersma, Niels L, Kremer, Daan, Knobbe, Tim J, Gan, C Tji, Nolte, Svea, Gomes-Neto, António W, Blokzijl, Hans, de Meijer, Vincent E, Damman, Kevin, Eisenga, Michele F, Drost, Gea, Elting, Jan Willem J, Touw, Daan J, Berger, Stefan P, Bakker, Stephan J L, van der Stouwe, A M Madelein

“…Solid organ transplant recipients (SOTR) frequently report tremor. Data concerning tremor-related impairment and its potential impact on health-related quality…”
Get full text

Smoking, Alcohol Intake and Torque Teno Virus in Stable Kidney Transplant Recipients by Doorenbos, Caecilia S E, Jonker, Jip, Hao, Jiasi, Gore, Edmund J, Kremer, Daan, Knobbe, Tim J, de Joode, Anoek A E, Sanders, Jan Stephan F, Thaunat, Olivier, Niesters, Hubert G M, Van Leer-Buter, Coretta C, Bakker, Stephan J L

“…Torque Teno Virus (TTV) is a non-pathogenic virus that is highly prevalent among kidney transplant recipients (KTRs). Its circulating load is associated with…”
Get full text

Creatine and creatinine quantified using nuclear magnetic resonance: A method validation study and clinical associations between circulating creatine and fatigue in kidney transplant recipients by Post, Adrian, Garcia, Erwin, Shalaurova, Irina, Matyus, Steven P., González-Delgado, Jessica M., Doorenbos, Caecilia S.E., van der Veen, Yvonne, Shah, Svati H., Kraus, William E., Kremer, Daan, Knobbe, Tim J., Bakker, Stephan J.L., Dullaart, Robin P.F., Connelly, Margery A.

“…•We presented a validated method for the simultaneous measurement of circulating creatine and creatinine.•This assay offers accurate and efficient…”
Get full text

Sleep quality, fatigue, societal participation and health-related quality of life in kidney transplant recipients: a cross-sectional and longitudinal cohort study by Knobbe, Tim J, Kremer, Daan, Eisenga, Michele F, van Londen, Marco, Annema, Coby, Bültmann, Ute, Kema, Ido P, Navis, Gerjan J, Berger, Stefan P, Bakker, Stephan J L

“…ABSTRACT Background Fatigue and impaired health-related quality of life (HRQoL) are common among kidney transplant recipients (KTR). We hypothesized that both…”
Get full text

Health-related quality of life is linked to the gut microbiome in kidney transplant recipients by Swarte, J. Casper, Knobbe, Tim J., Björk, Johannes R., Gacesa, Ranko, Nieuwenhuis, Lianne M., Zhang, Shuyan, Vila, Arnau Vich, Kremer, Daan, Douwes, Rianne M., Post, Adrian, Quint, Evelien E., Pol, Robert A., Jansen, Bernadien H., de Borst, Martin H., de Meijer, Vincent E., Blokzijl, Hans, Berger, Stefan P., Festen, Eleonora A. M., Zhernakova, Alexandra, Fu, Jingyuan, Harmsen, Hermie J. M., Bakker, Stephan J. L., Weersma, Rinse K.

“…Kidney transplant recipients (KTR) have impaired health-related quality of life (HRQoL) and suffer from intestinal dysbiosis. Increasing evidence shows that…”
Get full text

Urinary Copper Excretion Is Associated with Long-Term Graft Failure in Kidney Transplant Recipients by Yepes-Calderon, Manuela, Kremer, Daan, Post, Adrian, Sotomayor, Camilo G, Seidel, Ulrike, Huebbe, Patricia, Knobbe, Tim J, Lüersen, Kai, Eisenga, Michele F, Corpeleijn, Eva, de Borst, Martin H, Navis, Gerjan J, Rimbach, Gerald, Bakker, Stephan J L

“…In chronic kidney disease, proteinuria increases urinary copper excretion, inducing oxidative tubular damage and worsening kidney function. We investigated…”
Get more information

Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients by Swarte, J Casper, Zhang, Shuyan, Nieuwenhuis, Lianne M, Gacesa, Ranko, Knobbe, Tim J, De Meijer, Vincent E, Damman, Kevin, Verschuuren, Erik A M, Gan, Tji C, Fu, Jingyuan, Zhernakova, Alexandra, Harmsen, Hermie J M, Blokzijl, Hans, Bakker, Stephan J L, Björk, Johannes R, Weersma, Rinse K

“…Gut microbiome composition is associated with multiple diseases, but relatively little is known about its relationship with long-term outcome measures. While…”
Get more information