Search Results - "Knittel, Caroline H."
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Iodine-Mediated Tryptathionine Formation Facilitates the Synthesis of Amanitins
Published in Journal of the American Chemical Society (08-09-2021)“…Synthetic methods on the macrocyclization of peptides are of high interest since they facilitate the synthesis of various types of potentially bioactive…”
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Bioconjugation Strategies for Revealing the Roles of Lipids in Living Cells
Published in Accounts of chemical research (01-11-2022)“…Conspectus The structural boundaries of living cells are composed of numerous membrane-forming lipids. Lipids not only are crucial for the cellular…”
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A Convergent Total Synthesis of the Death Cap Toxin α‐Amanitin
Published in Angewandte Chemie International Edition (27-03-2020)“…The toxic bicyclic octapeptide α‐amanitin is mostly found in different species of the mushroom genus Amanita, with the death cap (Amanita phalloides) as one of…”
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Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL
Published in Angewandte Chemie International Edition (05-06-2023)“…Lanthipeptides are ribosomally‐synthesized natural products from bacteria featuring stable thioether‐crosslinks and various bioactivities. Herein, we report on…”
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Eine konvergente Totalsynthese des Pilztoxins α‐Amanitin
Published in Angewandte Chemie (27-03-2020)“…Das toxische bicyclische Octapeptid α‐Amanitin kommt hauptsächlich in Spezies der Pilzgattung Amanita vor, wobei der Grüne Knollenblätterpilz (Amanita…”
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Rücktitelbild: Eine konvergente Totalsynthese des Pilztoxins α‐Amanitin (Angew. Chem. 14/2020)
Published in Angewandte Chemie (27-03-2020)“…Das Gift des Knollenblätterpilzes, α‐Amanitin, steht seit einigen Jahren im Fokus als Bestandteil von Antikörper‐Wirkstoff‐Konjugaten für die Krebstherapie…”
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7
Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL
Published in Angewandte Chemie (05-06-2023)“…Lanthipeptides are ribosomally‐synthesized natural products from bacteria featuring stable thioether‐crosslinks and various bioactivities. Herein, we report on…”
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Back Cover: A Convergent Total Synthesis of the Death Cap Toxin α‐Amanitin (Angew. Chem. Int. Ed. 14/2020)
Published in Angewandte Chemie International Edition (27-03-2020)“…The death cap toxin α‐amanitin has received increasing attention as a toxin component of antibody–drug conjugates in cancer research. A new route to this…”
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