Search Results - "Knippenberg, Stefan"
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The influence of lipid membranes on fluorescent probes' optical properties
Published in Biochimica et biophysica acta. Biomembranes (01-02-2021)“…Organic fluorophores embedded in lipid bilayers can nowadays be described by a multiscale computational approach. Combining different length and time scales, a…”
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Conformational Changes as Driving Force for Phase Recognition: The Case of Laurdan
Published in Langmuir (03-09-2019)“…The development of a universal probe to assess the phase of a lipid membrane is one of the most ambitious goals for fluorescence spectroscopy. The ability of a…”
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Influence of Membrane Phase on the Optical Properties of DPH
Published in Molecules (Basel, Switzerland) (17-09-2020)“…The fluorescent molecule diphenylhexatriene (DPH) has been often used in combination with fluorescence anisotropy measurements, yet little is known regarding…”
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Hydration- and Temperature-Dependent Fluorescence Spectra of Laurdan Conformers in a DPPC Membrane
Published in Cells (Basel, Switzerland) (01-08-2024)“…The widely used Laurdan probe has two conformers, resulting in different optical properties when embedded in a lipid bilayer membrane, as demonstrated by our…”
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A Blue-Light-Emitting BODIPY Probe for Lipid Membranes
Published in Langmuir (12-04-2016)“…Here we describe a new BODIPY-based membrane probe (1) that provides an alternative to dialkylcarbocyanine dyes, such as DiI-C18, that can be excited in the…”
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Synthesis and Optical Properties of Pyrrolo[3,2‑b]pyrrole-2,5(1H,4H)‑dione (iDPP)-Based Molecules
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (04-04-2013)“…We describe the synthesis and photophysical properties of a series of derivatives of pyrrolo[3,2-b]pyrrole-2,5(1H,4H)-dione-3,6-diyl (iDPP) linked to two…”
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Push/Pull Effect as Driving Force for Different Optical Responses of Azobenzene in a Biological Environment
Published in Journal of physical chemistry. C (16-04-2020)“…The specific relationship between the alkyl tail lengths of four azobenzene probes embedded in DOPC liquid disorder membrane and their (non) linear optical…”
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Triggering On/Off States of Photoswitchable Probes in Biological Environments
Published in Journal of the American Chemical Society (29-03-2017)“…The use of hybrid systems for which the change in properties of one component triggers the change in properties of the other is of outmost importance when…”
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Theoretical Study of the Fragmentation Pathways of Norbornane in Its Doubly Ionized Ground State
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (25-10-2007)“…The potential energy surface of norbornane in its dicationic singlet ground state has been investigated in detail using density functional theory along with…”
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Environmental effects on the charge transfer properties of Graphene quantum dot based interfaces
Published in International journal of quantum chemistry (15-05-2019)“…Graphene quantum dots (GQD) are interesting materials due to the confined sizes which allow to exploit their optoelectronic properties, especially when they…”
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Probing the Shape and Stereochemistry of Molecular Orbitals in Locally Flexible Aromatic Chains: A Penning Ionization Electron Spectroscopy and Green's Function Study of the Electronic Structure of Biphenyl
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (24-11-2005)“…We report on the results of an exhaustive study of the interplay between the valence electronic structure, the topology and reactivity of orbitals, and the…”
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Generalized polarization and time-resolved fluorescence provide evidence for different populations of Laurdan in lipid vesicles
Published in Journal of photochemistry and photobiology. B, Biology (01-01-2024)“…The solvatochromic dye Laurdan is widely used in sensing the lipid packing of both model and biological membranes. The fluorescence emission maximum shifts…”
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Multiscale Modeling Unravels the Influence of Biomembranes on the Photochemical Properties of Embedded Anti-Oxidative Polyphenolic and Phenanthroline Chelating Dyes
Published in The journal of physical chemistry. B (12-01-2023)“…The embedding of caffeate methyl ester, the flavonoids luteolin and quercetin, and the o-phenanthroline and neocuproine in a liquid disordered lipid bilayer…”
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Cyanine dyes with tail length asymmetry enhance photoselection: A multiscale study on DiD probes in a liquid disordered membrane
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-01-2020)“…Visualization of membrane domains like lipid rafts in natural or artificial membranes is a crucial task for cell biology. For this purpose, fluorescence…”
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Dual photoisomerization mechanism of azobenzene embedded in a lipid membrane
Published in Journal of materials chemistry. B, Materials for biology and medicine (15-03-2023)“…The photoisomerization of chromophores embedded in biological environments is of high importance for biomedical applications, but it is still challenging to…”
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Exhibiting environment sensitive optical properties through multiscale modelling: A study of photoactivatable probes
Published in Journal of photochemistry and photobiology. A, Chemistry. (01-03-2022)“…[Display omitted] •Activatable fluorescent probe assesses tumor biomarker cyclooxygenase-2 enzyme.•The ANQ-IMC-6 probe relies on its good binding scaffold and…”
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Laurdan as a Molecular Rotor in Biological Environments
Published in ACS applied bio materials (16-12-2019)“…Laurdan is one of the most used fluorescent probes for lipid membrane phase recognition. Despite its wide use for optical techniques and its versatility as a…”
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Investigation into Biological Environments through (Non)linear Optics: A Multiscale Study of Laurdan Derivatives
Published in Journal of chemical theory and computation (13-12-2016)“…The fluorescent marker Laurdan and its new derivative, C-Laurdan, have been investigated by means of theoretical calculations in a DOPC lipid bilayer membrane…”
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Computational modeling reveals the influence of lipid membrane phases on fluorescent probes' optical properties
Published in European biophysics journal (2021)Get full text
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Combining (Non)linear Optical and Fluorescence Analysis of DiD To Enhance Lipid Phase Recognition
Published in Journal of chemical theory and computation (09-10-2018)“…The widespread interest in phase recognition of lipid membranes has led to the use of different optical techniques to enable differentiation of healthy and not…”
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