Search Results - "Knight, Y.E."

Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area by Bartsch, T., Levy, M.J., Knight, Y.E., Goadsby, P.J.

“…The novel neuropeptides orexin A and B are selectively synthesised in the lateral and posterior hypothalamus and are involved in hypothalamic regulation of…”
Get full text

The periaqueductal grey matter modulates trigeminovascular input: a role in migraine? by Knight, Y.E, Goadsby, P.J

“…The periaqueductal grey (PAG) region of the brainstem is a known modulator of somatic pain transmission. Migraine is likely to be due to episodic brain…”
Get full text

Occipital afferent activation of second order neurons in the trigeminocervical complex in rat by Le Doaré, K., Akerman, S., Holland, P.R., Lasalandra, M.P., Bergerot, A., Classey, J.D., Knight, Y.E., Goadsby, P.J.

“…Stimulation of the greater occipital nerve produces excitation of second order neurons in the trigeminocervical complex. Given that neck pain is very common in…”
Get full text

Inhibition of nociceptive dural input in the trigeminal nucleus caudalis by somatostatin receptor blockade in the posterior hypothalamus by Bartsch, T., Levy, M.J., Knight, Y.E., Goadsby, P.J.

“…Somatostatin is a neuromodulator in the central nervous system and is involved in the regulation of metabolic and neuroendocrine functions. Recent experimental…”
Get full text

The NMDA receptor antagonist MK-801 reduces Fos-like immunoreactivity within the trigeminocervical complex following superior sagittal sinus stimulation in the cat by Classey, J.D, Knight, Y.E, Goadsby, P.J

“…Expression of Fos protein is an indicator of neuronal perturbation and is readily observed in the caudal medulla and the spinal cord following…”
Get full text

Blockade of calcitonin gene-related peptide release after superior sagittal sinus stimulation in cat: a comparison of avitriptan and CP122,288 by Knight, Y.E., Edvinsson, L., Goadsby, P.J.

“…The pathophysiological basis for the pain of migraine has been the subject of substantial attention and must include activation of elements of the trigeminal…”
Get full text

Substance P blockade with the potent and centrally acting antagonist GR205171 does not effect central trigeminal activity with superior sagittal sinus stimulation by Goadsby, P.J, Hoskin, K.L, Knight, Y.E

“…The development and use of serotonin-1B/1D agonists to treat the acute attack of migraine has been a significant advance, but their vasoconstrictor effects…”
Get full text