Search Results - "Knight, William"

A Review of the Evidence for the Use of Telemedicine Within Stroke Systems of Care: A Scientific Statement From the American Heart Association/American Stroke Association by SCHWAMM, Lee H, HOLLOWAY, Robert G, MAYBERG, Marc, MEYER, Brett C, MEYERS, Philip M, SKALABRIN, Elaine, WECHSLER, Lawrence R, AMARENCO, Pierre, AUDEBERT, Heinrich J, BAKAS, Tamilyn, CHUMBLER, Neale R, HANDSCHU, Rene, JAUCH, Edward C, KNIGHT, William A, LEVINE, Steven R

“…The aim of this new statement is to provide a comprehensive and evidence-based review of the scientific data evaluating the use of telemedicine for stroke care…”
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MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A by Rocha, Agostinho G, Franco, Antonietta, Krezel, Andrzej M, Rumsey, Jeanne M, Alberti, Justin M, Knight, William C, Biris, Nikolaos, Zacharioudakis, Emmanouil, Janetka, James W, Baloh, Robert H, Kitsis, Richard N, Mochly-Rosen, Daria, Townsend, R Reid, Gavathiotis, Evripidis, Dorn, 2nd, Gerald W

“…Mitofusins (MFNs) promote fusion-mediated mitochondrial content exchange and subcellular trafficking. Mutations in cause neurodegenerative Charcot-Marie-Tooth…”
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Framing governance for a contested emerging technology:insights from AI policy by Ulnicane, Inga, Knight, William, Leach, Tonii, Stahl, Bernd Carsten, Wanjiku, Winter-Gladys

“…This paper examines how the governance in AI policy documents have been framed as way to resolve public controversies surrounding AI. It draws on the studies…”
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Endovascular Therapy for Patients With Acute Ischemic Stroke During the COVID-19 Pandemic: A Proposed Algorithm by Smith, Matthew S., Bonomo, Jordan, Knight, William A., Prestigiacomo, Charles J., Richards, Christopher T., Ramser, Evan, Adeoye, Opeolu, Bertsch, Stuart, Shirani, Peyman, Vagal, Achala, Fichtenbaum, Carl J., Housholder, Anne, Khatri, Pooja, Kleindorfer, Dawn O., Broderick, Joseph P., Grossman, Aaron W.

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Striatal oxidative damages and neuroinflammation correlate with progression and survival of Lewy body and Alzheimer diseases by Li, Huifangjie, Knight, William, Xu, Jinbin

“…Neurodegenerative diseases are a class of chronic and complex disorders featuring progressive loss of neurons in distinct brain areas. The mechanisms…”
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Emergency Neurological Life Support: Traumatic Spine Injury by Stein, Deborah M., Knight, William A.

“…Traumatic spine injuries (TSIs) carry significantly high risks of morbidity, mortality, and exorbitant health care costs from associated medical needs…”
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Does a high Mandard score really define a poor response to chemotherapy in oesophageal adenocarcinoma? by Knight, William R. C., Baker, Cara R., Griffin, Nyree, Wulaningsih, Wahyu, Kelly, Mark, Davies, Andrew R., Gossage, James A.

“…Background A high Mandard score implies a non-response to chemotherapy in oesophageal adenocarcinoma. However, some patients exhibit tumour volume reduction…”
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Time to consider animal data governance: perspectives from neuroscience by Eke, Damian, Ogoh, George, Knight, William, Stahl, Bernd

“…Scientific research relies mainly on multimodal, multidimensional big data generated from both animal and human organisms as well as technical data. However,…”
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The ED-SED Study: A Multicenter, Prospective Cohort Study of Practice Patterns and Clinical Outcomes Associated With Emergency Department SEDation for Mechanically Ventilated Patients by Fuller, Brian M., Roberts, Brian W., Mohr, Nicholas M., Knight, William A., Adeoye, Opeolu, Pappal, Ryan D., Marshall, Stacy, Alunday, Robert, Dettmer, Matthew, Goyal, Munish, Gibson, Colin, Levine, Brian J., Gardner-Gray, Jayna M., Mosier, Jarrod, Dargin, James, Mackay, Fraser, Johnson, Nicholas J., Lokhandwala, Sharukh, Hough, Catherine L., Tonna, Joseph E., Tsolinas, Rachel, Lin, Frederick, Qasim, Zaffer A., Harvey, Carrie E., Bassin, Benjamin, Stephens, Robert J., Yan, Yan, Carpenter, Christopher R., Kollef, Marin H., Avidan, Michael S.

“…OBJECTIVES:To characterize emergency department sedation practices in mechanically ventilated patients, and test the hypothesis that deep sedation in the…”
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Why Is It Too Cold? Towards a Mechanistic Understanding of Cold‐Water Pollution Effects on Recruitment of an Imperiled Warmwater Fish by Gilbert, Eliza I., Diver, Tracy A., Mussmann, Steven M., Saltzgiver, Melody J., Knight, William K., Durst, Scott L., Farrington, Michael A., Clark Barkalow, Stephani L., Tobler, Michael, Franssen, Nathan R.

“…ABSTRACT Environmental temperature shapes the ontogeny of ectotherms by influencing rates of growth and development which can be key determinants of survival…”
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Genetic encoding of the post-translational modification 2-hydroxyisobutyryl-lysine by Knight, William A, Cropp, T Ashton

“…We report the synthesis and genetic encoding of a recently discovered post-translational modification, 2-hydroxyisobutyryl-lysine, to the genetic code of E…”
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Analysis of outcomes of a transoral circular stapled anastomosis following major upper gastrointestinal cancer resection by Foley, Daniel M, Emanuwa, Emudiaga J E, Knight, William R C, Baker, Cara R, Kelly, Mark, McEwan, Ricardo, Zylstra, Janine, Davies, Andrew R, Gossage, James A

“…Esophageal anastomoses performed following esophagectomy and total gastrectomy are technically challenging with a significant risk of anastomotic leak. A safe,…”
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Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype by Li, Huifangjie, Knight, William C, Yang, Pengfei, Guo, Yingqiu, Perlmutter, Joel S, Morris, John C, Bateman, Randall J, Benzinger, Tammie L S, Xu, Jinbin

“…We found interactions between dopamine and oxidative damage in the striatum involved in advanced neurodegeneration, which probably change the microglial…”
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Responsible Data Governance of Neuroscience Big Data by Fothergill, B Tyr, Knight, William, Stahl, Bernd Carsten, Ulnicane, Inga

“…Current discussions of the ethical aspects of big data are shaped by concerns regarding the social consequences of both the widespread adoption of machine…”
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Impact of Misting Systems on Local Particulate Matter (PM) Levels by Knight, William L., Fraser, Matthew P., Herckes, Pierre

“…In hot, arid environments, many outdoor spaces are cooled by misting systems. These systems spray a fine mist of water droplets that cool down the surrounding…”
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Predicting response to neoadjuvant chemotherapy in patients with oesophageal adenocarcinoma by Bott, Rebecca K, George, Gincy, McEwen, Ricardo, Zylstra, Janine, Knight, William R C, Baker, Cara R, Kelly, Mark, Griffin, Nyree, McAddy, Naami, Maisey, Nick, Van Hemelrijck, Mieke, Gossage, James A, Lagergren, Jesper, Davies, Andrew R

“…Neoadjuvant chemotherapy is often used prior to surgical resection for oesophageal adenocarcinoma but remains ineffective in a high proportion of patients. The…”
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DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat by Nistala, Ravi, Habibi, Javad, Aroor, Annayya, Sowers, James R., Hayden, Melvin R., Meuth, Alex, Knight, William, Hancock, Tamara, Klein, Thomas, DeMarco, Vincent G., Whaley‐Connell, Adam

“…Objective Obesity‐related glomerulopathy is characterized initially by glomerular hyperfiltration with hypertrophy and then development of proteinuria…”
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From Responsible Research and Innovation to responsibility by design by Stahl, Bernd Carsten, Akintoye, Simisola, Bitsch, Lise, Bringedal, Berit, Eke, Damian, Farisco, Michele, Grasenick, Karin, Guerrero, Manuel, Knight, William, Leach, Tonii, Nyholm, Sven, Ogoh, George, Rosemann, Achim, Salles, Arleen, Trattnig, Julia, Ulnicane, Inga

“…Drawing on more than eight years working to implement Responsible Research and Innovation (RRI) in the Human Brain Project, a large EU-funded research project…”
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Adjuvant therapy following neoadjuvant chemotherapy and surgery for oesophageal adenocarcinoma in patients with clear resection margins by Bott, Rebecca K, Beckmann, Kerri, Zylstra, Janine, Wilkinson, Michelle J, Knight, William R C, Baker, Cara R, Kelly, Mark, Maisey, Nick, Waters, Justin, Van Hemelrijck, Mieke, Smyth, Elizabeth C, Allum, William H, Lagergren, Jesper, Gossage, James A, Cunningham, David, Davies, Andrew R

“…The role of adjuvant therapy in patients with oesophagogastric adenocarcinoma treated by neoadjuvant chemotherapy (NAC) and surgery is contentious. In UK…”
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KEY Careers: Increasing Retention and Graduation Rates With Career Interventions by Clayton, Karley, Wessel, Roger D., McAtee, Jim, Knight, William E.

“…The purpose of the study was to investigate how promoting participation in KEY Careers, a career intervention program available to all incoming matriculates,…”
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