Search Results - "Knight, Michael L."

Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection by Kamel, Wael, Noerenberg, Marko, Cerikan, Berati, Chen, Honglin, Järvelin, Aino I., Kammoun, Mohamed, Lee, Jeffrey Y., Shuai, Ni, Garcia-Moreno, Manuel, Andrejeva, Anna, Deery, Michael J., Johnson, Natasha, Neufeldt, Christopher J., Cortese, Mirko, Knight, Michael L., Lilley, Kathryn S., Martinez, Javier, Davis, Ilan, Bartenschlager, Ralf, Mohammed, Shabaz, Castello, Alfredo

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins…”
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Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress by Mendonça, Luiza, Howe, Andrew, Gilchrist, James B., Sheng, Yuewen, Sun, Dapeng, Knight, Michael L., Zanetti-Domingues, Laura C., Bateman, Benji, Krebs, Anna-Sophia, Chen, Long, Radecke, Julika, Li, Vivian D., Ni, Tao, Kounatidis, Ilias, Koronfel, Mohamed A., Szynkiewicz, Marta, Harkiolaki, Maria, Martin-Fernandez, Marisa L., James, William, Zhang, Peijun

“…Since the outbreak of the SARS-CoV-2 pandemic, there have been intense structural studies on purified viral components and inactivated viruses. However,…”
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The structure of the influenza A virus genome by Dadonaite, Bernadeta, Gilbertson, Brad, Knight, Michael L., Trifkovic, Sanja, Rockman, Steven, Laederach, Alain, Brown, Lorena E., Fodor, Ervin, Bauer, David L. V.

“…Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome consists of eight single-stranded viral RNA segments contained in separate…”
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Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility by Coria, Aaztli, Wienecke, Anastacia, Knight, Michael L, Desirò, Daniel, Laederach, Alain, Borodavka, Alexander

“…Due to genome segmentation, rotaviruses must co-package eleven distinct genomic RNAs. The packaging is mediated by virus-encoded RNA chaperones, such as the…”
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Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 by Huo, Jiandong, Le Bas, Audrey, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.

“…The SARS-CoV-2 virus is more transmissible than previous coronaviruses and causes a more serious illness than influenza. The SARS-CoV-2 receptor binding domain…”
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Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient by Zhou, Daming, Duyvesteyn, Helen M. E., Chen, Cheng-Pin, Huang, Chung-Guei, Chen, Ting-Hua, Shih, Shin-Ru, Lin, Yi-Chun, Cheng, Chien-Yu, Cheng, Shu-Hsing, Huang, Yhu-Chering, Lin, Tzou-Yien, Ma, Che, Huo, Jiandong, Carrique, Loic, Malinauskas, Tomas, Ruza, Reinis R., Shah, Pranav N. M., Tan, Tiong Kit, Rijal, Pramila, Donat, Robert F., Godwin, Kerry, Buttigieg, Karen R., Tree, Julia A., Radecke, Julika, Paterson, Neil G., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Carroll, Miles W., Gilbert-Jaramillo, Javier, Knight, Michael L., James, William, Owens, Raymond J., Naismith, James H., Townsend, Alain R., Fry, Elizabeth E., Zhao, Yuguang, Ren, Jingshan, Stuart, David I., Huang, Kuan-Ying A.

“…The COVID-19 pandemic has had an unprecedented health and economic impact and there are currently no approved therapies. We have isolated an antibody, EY6A,…”
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The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme by Walker, Alexander P, Fan, Haitian, Keown, Jeremy R, Knight, Michael L, Grimes, Jonathan M, Fodor, Ervin

“…Abstract SARS-CoV-2 is a positive-sense RNA virus responsible for the Coronavirus Disease 2019 (COVID-19) pandemic, which continues to cause significant…”
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Inclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity by Chauveau, Lise, Bridgeman, Anne, Tan, Tiong K, Beveridge, Ryan, Frost, Joe N, Rijal, Pramila, Pedroza-Pacheco, Isabela, Partridge, Thomas, Gilbert-Jaramillo, Javier, Knight, Michael L, Liu, Xu, Russell, Rebecca A, Borrow, Persephone, Drakesmith, Hal, Townsend, Alain R, Rehwinkel, Jan

“…Cyclic GMP-AMP (cGAMP) is an immunostimulatory molecule produced by cGAS that activates STING. cGAMP is an adjuvant when administered alongside antigens. cGAMP…”
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Structure of an H3N2 influenza virus nucleoprotein by Knight, Michael L., Fan, Haitian, Bauer, David L. V., Grimes, Jonathan M., Fodor, Ervin, Keown, Jeremy R.

“…Influenza A viruses of the H1N1 and H3N2 subtypes are responsible for seasonal epidemic events. The influenza nucleoprotein (NP) binds to the viral genomic RNA…”
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Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using Pichia pastoris by Sherry, Lee, Grehan, Keith, Snowden, Joseph S, Knight, Michael L, Adeyemi, Oluwapelumi O, Rowlands, David J, Stonehouse, Nicola J

“…For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during viral…”
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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 by Huo, Jiandong, Bas, Audrey Le, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41594-021-00566-w…”
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Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2 by Huo, Jiangdong, Le Bas, Audrey, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern by Skelly, Donal T., Harding, Adam C., Gilbert-Jaramillo, Javier, Knight, Michael L., Longet, Stephanie, Brown, Anthony, Adele, Sandra, Adland, Emily, Brown, Helen, Tipton, Tom, Stafford, Lizzie, Mentzer, Alexander J., Johnson, Síle A., Amini, Ali, Tan, Tiong Kit, Schimanski, Lisa, Huang, Kuan-Ying A., Rijal, Pramila, Frater, John, Goulder, Philip, Conlon, Christopher P., Jeffery, Katie, Dold, Christina, Pollard, Andrew J., Sigal, Alex, de Oliveira, Tulio, Townsend, Alain R., Klenerman, Paul, Dunachie, Susanna J., Barnes, Eleanor, Carroll, Miles W., James, William S.

“…The extent to which immune responses to natural infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and immunization with vaccines…”
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Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using italic toggle="yes">Pichia pastoris /italic by Lee Sherry, Keith Grehan, Joseph S. Snowden, Michael L. Knight, Oluwapelumi O. Adeyemi, David J. Rowlands, Nicola J. Stonehouse

“…ABSTRACT For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during…”
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