Search Results - "Knight, Colette"
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Heart Failure: An Underappreciated Complication of Diabetes. A Consensus Report of the American Diabetes Association
Published in Diabetes care (07-07-2022)“…Heart failure (HF) has been recognized as a common complication of diabetes, with a prevalence of up to 22% in individuals with diabetes and increasing…”
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Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors
Published in Nature communications (13-10-2014)“…Insulin integrates hepatic glucose and lipid metabolism, directing nutrients to storage as glycogen and triglyceride. In type 2 diabetes, levels of the former…”
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SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
Published in Cell metabolism (01-10-2008)“…In yeast, worms, and flies, an extra copy of the gene encoding the Sirtuin Sir2 increases metabolic efficiency, as does administration of polyphenols like…”
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Stem Cell Educator therapy in type 1 diabetes: From the bench to clinical trials
Published in Autoimmunity reviews (01-05-2022)“…Type 1 diabetes (T1D) is an autoimmune disease that causes a deficit of pancreatic islet β cells. Millions of individuals worldwide have T1D, and its incidence…”
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Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions
Published in Cell reports (Cambridge) (23-06-2015)“…Obesity is associated with higher incidence of cancer, but the predisposing mechanisms remain poorly understood. The NAD+-dependent deacetylase…”
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Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats
Published in Diabetes (New York, N.Y.) (01-11-2011)“…Sirtuin 1 (SIRT1) and its activator resveratrol are emerging as major regulators of metabolic processes. We investigate the site of resveratrol action on…”
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Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700
Published in Diabetes (New York, N.Y.) (01-12-2017)Get full text
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Erratum. Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats. Diabetes 2011;60:2691-2700
Published in Diabetes (New York, N.Y.) (01-12-2017)Get full text
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Evidence for a Role of Proline and Hypothalamic Astrocytes in the Regulation of Glucose Metabolism in Rats
Published in Diabetes (New York, N.Y.) (01-04-2013)“…The metabolism of lactate to pyruvate in the mediobasal hypothalamus (MBH) regulates hepatic glucose production. Because astrocytes and neurons are…”
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Acute Exposure of the Mediobasal Hypothalamus to Amyloid-β25-35 Perturbs Hepatic Glucose Metabolism
Published in Journal of Alzheimer's disease (26-06-2015)“…Patients with Alzheimer's disease (AD) have a higher risk for developing insulin resistance and diabetes. Amyloid plaques, a hallmark of AD, are composed of…”
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A Rare Case of Hypercalcemic Crisis Secondary to a Squamous Cell Carcinoma Arising from a Nonhealing Ulcer
Published in AACE clinical case reports (01-01-2017)“…Objective: To report a case of hypercalcemic crisis in an African American male who presented with a nonhealing ulcer which was later found to be squamous cell…”
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8264 An Interesting Case of Hypophysitis in a Young Woman
Published in Journal of the Endocrine Society (05-10-2024)“…Abstract Disclosure: A. Garcia: None. R. Sharma: None. C.M. Knight: None. Background Hypophysitis is an uncommon disorder and presents with clinical signs and…”
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2237-PUB: Diabetes Inside: Regional Collaborative to Improve DM and CVD Care Quality
Published in Diabetes (New York, N.Y.) (01-06-2020)“…The American Diabetes Association (ADA) and the American Heart Association launched a multi-faceted national partnership in 2018, Know Diabetes by Heart™, to…”
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Offene Bildungsressourcen an der RWTH Aachen
Published in Informationspraxis (01-04-2021)“…Als Folge der weltweiten Pandemie des Coronavirus im Jahr 2020 sind viele Universitäten kurzfristig gezwungen, zumindest vorübergehend auf Online-Lehre…”
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Abstract 11944: A Unique Presentation of Sheehan’s Syndrome With Acute Pericarditis
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionSheehan’s syndrome (post-partum pituitary hemorrhage) is a rare but fatal complication. Depending upon the pituitary damage, secretion of one or…”
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Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats
Published in Diabetes (New York, N.Y.) (2011)Get full text
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Integrated Control Of Hepatic Lipogenesis Vs. Glucose Production Requires FoxO Transcription Factors
Published in Nature communications (13-10-2014)“…Insulin integrates hepatic glucose and lipid metabolism, directing nutrients to storage as glycogen and triglyceride. In type 2 diabetes, levels of the former…”
Get full text
Journal Article