Search Results - "Knibbe, Catherijne A"

Impact of Obesity on Drug Metabolism and Elimination in Adults and Children by Brill, Margreke J. E., Diepstraten, Jeroen, van Rongen, Anne, van Kralingen, Simone, van den Anker, John N., Knibbe, Catherijne A. J.

“…The prevalence of obesity in adults and children is rapidly increasing across the world. Several general (patho)physiological alterations associated with…”
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Impact of Bariatric Surgery in the Short and Long Term: A Need for Time-Dependent Dosing of Drugs by Lau, Cedric, van Kesteren, Charlotte, Smeenk, Robert, Huitema, Alwin, Knibbe, Catherijne A. J.

“…Sparse information is available on pharmacokinetic changes of drugs over time after bariatric surgery. By reviewing the literature on the short- and long-term…”
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Effect of Intravenous Paracetamol on Postoperative Morphine Requirements in Neonates and Infants Undergoing Major Noncardiac Surgery: A Randomized Controlled Trial by Ceelie, Ilse, de Wildt, Saskia N, van Dijk, Monique, van den Berg, Margreeth M. J, van den Bosch, Gerbrich E, Duivenvoorden, Hugo J, de Leeuw, Tom G, Mathôt, Ron, Knibbe, Catherijne A. J, Tibboel, Dick

“…IMPORTANCE Continuous morphine infusion as standard postoperative analgesic therapy in young infants is associated with unwanted adverse effects such as…”
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A randomized controlled trial of daily sedation interruption in critically ill children by Vet, Nienke J., de Wildt, Saskia N., Verlaat, Carin W. M., Knibbe, Catherijne A. J., Mooij, Miriam G., van Woensel, Job B. M., van Rosmalen, Joost, Tibboel, Dick, de Hoog, Matthijs

“…Purpose To compare daily sedation interruption plus protocolized sedation (DSI + PS) to protocolized sedation only (PS) in critically ill children. Methods In…”
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Amikacin Pharmacokinetics To Optimize Dosing in Neonates with Perinatal Asphyxia Treated with Hypothermia by Cristea, Sinziana, Smits, Anne, Kulo, Aida, Knibbe, Catherijne A J, van Weissenbruch, Mirjam, Krekels, Elke H J, Allegaert, Karel

“…Aminoglycoside pharmacokinetics (PK) is expected to change in neonates with perinatal asphyxia treated with therapeutic hypothermia (PATH). Several amikacin…”
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Developmental Changes in the Expression and Function of Cytochrome P450 3A Isoforms: Evidence from In Vitro and In Vivo Investigations by Ince, Ibrahim, Knibbe, Catherijne A. J., Danhof, Meindert, de Wildt, Saskia N.

“…The aim of this review is to discuss our current understanding of the developmental changes of the drug-metabolizing enzyme cytochrome P450 (CYP) 3A and its…”
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Midazolam Infusion and Disease Severity Affect the Level of Sedation in Children: A Parametric Time-to-Event Analysis by Upadhyay, Parth J., Vet, Nienke J., Goulooze, Sebastiaan C., Krekels, Elke H. J., de Wildt, Saskia N., Knibbe, Catherijne A. J.

“…Aim In critically ill mechanically ventilated children, midazolam is used first line for sedation, however its exact sedative effects have been difficult to…”
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Prediction of glomerular filtration rate maturation across preterm and term neonates and young infants using inulin as marker by Wu, Yunjiao, Allegaert, Karel, Flint, Robert B., Simons, Sinno H. P., Krekels, Elke H. J., Knibbe, Catherijne A. J., Völler, Swantje

“…Describing glomerular filtration rate (GFR) maturation across the heterogeneous population of preterm and term neonates and infants is important to predict the…”
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The role of population PK–PD modelling in paediatric clinical research by De Cock, Roosmarijn F. W., Piana, Chiara, Krekels, Elke H. J., Danhof, Meindert, Allegaert, Karel, Knibbe, Catherijne A. J.

“…Children differ from adults in their response to drugs. While this may be the result of changes in dose exposure (pharmacokinetics [PK]) and/or exposure…”
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When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers? by Wu, Yunjiao, Allegaert, Karel, Flint, Robert B., Goulooze, Sebastiaan C., Välitalo, Pyry A. J., de Hoog, Matthijs, Mulla, Hussain, Sherwin, Catherine M. T., Simons, Sinno H. P., Krekels, Elke H. J., Knibbe, Catherijne A. J., Völler, Swantje

“…Aims Whether and when glomerular filtration rate (GFR) in preterms catches up with term peers is unknown. This study aims to develop a GFR maturation model for…”
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Maturation of Paracetamol Elimination Routes in Preterm Neonates Born Below 32 Weeks of Gestation by Wu, Yunjiao, Völler, Swantje, Krekels, Elke H. J., Roofthooft, Daniëlla W. E., Simons, Sinno H. P., Tibboel, Dick, Flint, Robert B., Knibbe, Catherijne A. J.

“…Purpose Despite being off-label, intravenous paracetamol (PCM) is increasingly used to control mild-to-moderate pain in preterm neonates. Here we aim to…”
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The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients Before and One Year After Bariatric Surgery by Brill, Margreke J., van Rongen, Anne, van Dongen, Eric P., van Ramshorst, Bert, Hazebroek, Eric J., Darwich, Adam S., Rostami-Hodjegan, Amin, Knibbe, Catherijne A.

“…Purpose Bariatric surgery is nowadays commonly applied as treatment for morbid obesity (BMI > 40 kg/m 2 ). As information about the effects of this procedure…”
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Tobramycin Clearance Is Best Described by Renal Function Estimates in Obese and Non-obese Individuals: Results of a Prospective Rich Sampling Pharmacokinetic Study by Smit, Cornelis, Wasmann, Roeland E., Wiezer, Marinus J., van Dongen, Hendricus P. A., Mouton, Johan W., Brüggemann, Roger J. M., Knibbe, Catherijne A. J.

“…Purpose Tobramycin is an aminoglycoside antibiotic of which the 24 h exposure correlates with efficacy. Recently, we found that clearance of the aminoglycoside…”
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Impact of Obesity on Hepatic Drug Clearance: What are the Influential Variables? by Zhang, Tan, Calvier, Elisa A. M., Krekels, Elke H. J., Knibbe, Catherijne A. J.

“…Drug clearance in obese subjects varies widely among different drugs and across subjects with different severity of obesity. This study investigates…”
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Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling by Janssen, Esther J H, Välitalo, Pyry A J, Allegaert, Karel, de Cock, Roosmarijn F W, Simons, Sinno H P, Sherwin, Catherine M T, Mouton, Johan W, van den Anker, Johannes N, Knibbe, Catherijne A J

“…Because of the recent awareness that vancomycin doses should aim to meet a target area under the concentration-time curve (AUC) instead of trough…”
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Simultaneous Pharmacokinetic Modeling of Gentamicin, Tobramycin and Vancomycin Clearance from Neonates to Adults: Towards a Semi-physiological Function for Maturation in Glomerular Filtration by De Cock, Roosmarijn F. W., Allegaert, Karel, Brussee, Janneke M., Sherwin, Catherine M. T., Mulla, Hussain, de Hoog, Matthijs, van den Anker, Johannes N., Danhof, Meindert, Knibbe, Catherijne A. J.

“…ABSTRACT Purpose Since glomerular filtration rate (GFR) is responsible for the elimination of a large number of water-soluble drugs, the aim of this study was…”
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Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations by de Hoogd, Sjoerd, Goulooze, Sebastiaan C., Valkenburg, Abraham J., Krekels, Elke H. J., van Dijk, Monique, Tibboel, Dick, Knibbe, Catherijne A. J.

“…Background Morphine is commonly used for postoperative analgesia in children. Here we studied the pharmacodynamics of morphine in children after cardiac…”
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Maturation of the Glomerular Filtration Rate in Neonates, as Reflected by Amikacin Clearance by De Cock, Roosmarijn F. W., Allegaert, Karel, Schreuder, Michiel F., Sherwin, Catherine M. T., de Hoog, Matthijs, van den Anker, Johannes N., Danhof, Meindert, Knibbe, Catherijne A. J.

“…Background and Objectives During the newborn period and early infancy, renal function matures, resulting in changes in the glomerular filtration rate (GFR)…”
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Midazolam Pharmacokinetics in Morbidly Obese Patients Following Semi-Simultaneous Oral and Intravenous Administration: A Comparison with Healthy Volunteers by Brill, Margreke J. E., van Rongen, Anne, Houwink, Aletta P. I., Burggraaf, Jacobus, van Ramshorst, Bert, Wiezer, René J., van Dongen, Eric P. A., Knibbe, Catherijne A. J.

“…Background While in vitro and animal studies have shown reduced cytochrome P450 (CYP) 3A activity due to obesity, clinical studies in (morbidly) obese patients…”
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Association between anti-thymocyte globulin exposure and CD4+ immune reconstitution in paediatric haemopoietic cell transplantation: a multicentre, retrospective pharmacodynamic cohort analysis by Admiraal, Rick, MD, van Kesteren, Charlotte, PhD, Jol-van der Zijde, Cornelia M, BSc, Lankester, Arjan C, MD, Bierings, Marc B, MD, Egberts, Toine C G, Prof, van Tol, Maarten J D, PhD, Knibbe, Catherijne A J, Prof, Bredius, Robbert G M, MD, Boelens, Jaap J, Dr

“…Summary Background Anti-thymocyte globulin (ATG) was introduced into the conditioning regimen in haemopoietic cell transplantation (HCT) to prevent…”
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