Search Results - "Knezevic, Lea"

Prolonged T-cell activation and long COVID symptoms independently associate with severe COVID-19 at 3 months by Santopaolo, Marianna, Gregorova, Michaela, Hamilton, Fergus, Arnold, David, Long, Anna, Lacey, Aurora, Oliver, Elizabeth, Halliday, Alice, Baum, Holly, Hamilton, Kristy, Milligan, Rachel, Pearce, Olivia, Knezevic, Lea, Morales Aza, Begonia, Milne, Alice, Milodowski, Emily, Jones, Eben, Lazarus, Rajeka, Goenka, Anu, Finn, Adam, Maskell, Nicholas, Davidson, Andrew D, Gillespie, Kathleen, Wooldridge, Linda, Rivino, Laura

“…Coronavirus disease-19 (COVID-19) causes immune perturbations which may persist long term, and patients frequently report ongoing symptoms for months after…”
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Engineering Blood and Lymphatic Microvascular Networks in Fibrin Matrices by Knezevic, Lea, Schaupper, Mira, Mühleder, Severin, Schimek, Katharina, Hasenberg, Tobias, Marx, Uwe, Priglinger, Eleni, Redl, Heinz, Holnthoner, Wolfgang

“…Vascular network engineering is essential for nutrient delivery to tissue-engineered constructs and, consequently, their survival. In addition, the…”
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Development and evaluation of low-volume tests to detect and characterize antibodies to SARS-CoV-2 by Halliday, Alice, Long, Anna E, Baum, Holly E, Thomas, Amy C, Shelley, Kathryn L, Oliver, Elizabeth, Gupta, Kapil, Francis, Ore, Williamson, Maia Kavanagh, Di Bartolo, Natalie, Randell, Matthew J, Ben-Khoud, Yassin, Kelland, Ilana, Mortimer, Georgina, Ball, Olivia, Plumptre, Charlie, Chandler, Kyla, Obst, Ulrike, Secchi, Massimiliano, Piemonti, Lorenzo, Lampasona, Vito, Smith, Joyce, Gregorova, Michaela, Knezevic, Lea, Metz, Jane, Barr, Rachael, Morales-Aza, Begonia, Oliver, Jennifer, Collingwood, Lucy, Hitchings, Benjamin, Ring, Susan, Wooldridge, Linda, Rivino, Laura, Timpson, Nicholas, McKernon, Jorgen, Muir, Peter, Hamilton, Fergus, Arnold, David, Woolfson, Derek N, Goenka, Anu, Davidson, Andrew D, Toye, Ashley M, Berger, Imre, Bailey, Mick, Gillespie, Kathleen M, Williams, Alistair J K, Finn, Adam

“…Low-volume antibody assays can be used to track SARS-CoV-2 infection rates in settings where active testing for virus is limited and remote sampling is…”
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Sensitivity Tuning of Tcr-Engineered T-Cells Using CD8 Co-Receptor Variants by Knezevic, Lea

“…TCR-engineered T-cells are a promising tool for the treatment of haematological and solid malignancies. The key to the success of T-cell therapy lies in the…”
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High-affinity CD8 variants enhance the sensitivity of pMHCI antigen recognition via low-affinity TCRs by Knezevic, Lea, Wachsmann, Tassilo L.A., Francis, Ore, Dockree, Tamsin, Bridgeman, John S., Wouters, Anne, de Wet, Ben, Cole, David K., Clement, Mathew, McLaren, James E., Gostick, Emma, Ladell, Kristin, Llewellyn-Lacey, Sian, Price, David A., van den Berg, Hugo A., Tabi, Zsuzsanna, Sessions, Richard B., Heemskerk, Mirjam H.M., Wooldridge, Linda

“…The recognition of cell surface presented peptide-Major Histocompatibility Complex Class I (pMHCI) molecules by CD8 T-cells involves cooperative binding of the…”
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CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor by Clement, Mathew, Knezevic, Lea, Dockree, Tamsin, McLaren, James E., Ladell, Kristin, Miners, Kelly L., Llewellyn-Lacey, Sian, Rubina, Anzelika, Francis, Ore, Cole, David K., Sewell, Andrew K., Bridgeman, John S., Price, David A., van den Berg, Hugo A., Wooldridge, Linda

“…CD8⁺ T cells are inherently cross-reactive and recognize numerous peptide antigens in the context of a given major histocompatibility complex class I (MHCI)…”
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Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2 by Goenka, Anu, Halliday, Alice, Gregorova, Michaela, Milodowski, Emily, Thomas, Amy, Williamson, Maia Kavanagh, Baum, Holly, Oliver, Elizabeth, Long, Anna E., Knezevic, Lea, Williams, Alistair J.K., Lampasona, Vito, Piemonti, Lorenzo, Gupta, Kapil, Di Bartolo, Natalie, Berger, Imre, Toye, Ashley M., Vipond, Barry, Muir, Peter, Bernatoniene, Jolanta, Bailey, Mick, Gillespie, Kathleen M., Davidson, Andrew D., Wooldridge, Linda, Rivino, Laura, Finn, Adam

“…Severe COVID-19 appears rare in children. This is unexpected, especially in young infants, who are vulnerable to severe disease caused by other respiratory…”
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404. Development of Combinational Cellular Immunotherapy to Treat Pediatric Acute Myeloid Leukemia Patients by vanTil, Niek P., Knežević, Lea, Plantinga, Maud, de Haar, Colin, Hoeben, Rob C., Gonçalves, Manuel A., Nierkens, Stefan, Boelens, Jaap Jan

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