Search Results - "Knevel, Rachel"

Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis by Amariuta, Tiffany, Luo, Yang, Knevel, Rachel, Okada, Yukinori, Raychaudhuri, Soumya

“…Summary Rheumatoid arthritis (RA) risk has a large genetic component (~60%) that is still not fully understood. This has hampered the design of effective…”
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E-health as a sine qua non for modern healthcare by Knevel, Rachel, Hügle, Thomas

“…In each era we need to balance between being able to provide care with our “technical skill, scientific knowledge, and human understanding” (Harrison's…”
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Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage by Shi, Jing, Knevel, Rachel, Suwannalai, Parawee, van der Linden, Michael P, Janssen, George M. C, van Veelen, Peter A, Levarht, Nivine E. W, van der Helm-van Mil, Annette H. M, Cerami, Anthony, Huizinga, Tom W. J, Toes, Rene E. M, Trouw, Leendert A

“…Autoimmune responses against posttranslationally modified antigens are a hallmark of several autoimmune diseases. For example, antibodies against citrullinated…”
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Recommendation to implementation of remote patient monitoring in rheumatology: lessons learned and barriers to take by Hamann, Philip, Knitza, Johannes, Kuhn, Sebastian, Knevel, Rachel

“…Remote patient monitoring (RPM) leverages advanced technology to monitor and manage patients’ health remotely and continuously. In 2022 European Alliance of…”
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Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity by Curtis, Jeffrey R., van der Helm‐van Mil, Annette H., Knevel, Rachel, Huizinga, Tom W., Haney, Douglas J., Shen, Yijing, Ramanujan, Saroja, Cavet, Guy, Centola, Michael, Hesterberg, Lyndal K., Chernoff, David, Ford, Kerri, Shadick, Nancy A., Hamburger, Max, Fleischmann, Roy, Keystone, Edward, Weinblatt, Michael E.

“…Objective Quantitative assessment of disease activity in rheumatoid arthritis (RA) is important for patient management, and additional objective information…”
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EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria by van der Heijde, Désirée, van der Helm-van Mil, Annette H M, Aletaha, Daniel, Bingham, Clifton O, Burmester, Gerd R, Dougados, Maxime, Emery, Paul, Felson, David, Knevel, Rachel, Kvien, Tore K, Landewé, Robert B M, Lukas, Cédric, McInnes, Iain, Silman, Alan J, Smolen, Josef S, Stanislawska-Biernat, Ewa, Zink, Angela, Combe, Bernard

“…The aim of this report was to propose a definition for erosive disease in the context of inflammatory arthritis in light of the 2010 American College of…”
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Medical Records-Based Genetic Studies of the Complement System by Khan, Atlas, Shang, Ning, Petukhova, Lynn, Zhang, Jun, Shen, Yufeng, Hebbring, Scott J, Moncrieffe, Halima, Kottyan, Leah C, Namjou-Khales, Bahram, Knevel, Rachel, Raychaudhuri, Soumya, Karlson, Elizabeth W, Harley, John B, Stanaway, Ian B, Crosslin, David, Denny, Joshua C, Elkind, Mitchell S V, Gharavi, Ali G, Hripcsak, George, Weng, Chunhua, Kiryluk, Krzysztof

“…Genetic variants in complement genes have been associated with a wide range of human disease states, but well-powered genetic association studies of complement…”
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Baseline serum adipokine levels predict radiographic progression in early rheumatoid arthritis by Klein‐Wieringa, Inge R., van der Linden, Michael P. M., Knevel, Rachel, Kwekkeboom, Joanneke C., van Beelen, Els, Huizinga, Tom W. J., van der Helm‐van Mil, Annette, Kloppenburg, Margreet, Toes, René E. M., Ioan‐Facsinay, Andreea

“…Objective Adipose tissue can secrete soluble mediators (adipokines) with potent immune regulatory functions. Some adipokines have been previously associated…”
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Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases by Traylor, Matthew, Knevel, Rachel, Cui, Jing, Taylor, John, Harm-Jan, Westra, Conaghan, Philip G, Cope, Andrew P, Curtis, Charles, Emery, Paul, Newhouse, Stephen, Patel, Hamel, Steer, Sophia, Gregersen, Peter, Shadick, Nancy A, Weinblatt, Michael E, Van Der Helm-van Mil, Annette, Barrett, Jennifer H, Morgan, Ann W, Lewis, Cathryn M, Scott, Ian C

“…Previous studies of radiological damage in rheumatoid arthritis (RA) have used candidate-gene approaches, or evaluated single genome-wide association studies…”
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An evaluation of molecular and clinical remission in rheumatoid arthritis by assessing radiographic progression by van der Helm-van Mil, Annette H M, Knevel, Rachel, Cavet, Guy, Huizinga, Tom W J, Haney, Douglas J

“…To determine whether molecular remission defined by a multi-biomarker disease activity (MBDA) score predicts a reduced risk of joint damage progression, and…”
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Genetic predisposition of the severity of joint destruction in rheumatoid arthritis: a population-based study by Knevel, Rachel, Gröndal, Gerður, Huizinga, Tom W J, Visser, A Willemien, Jónsson, Helgi, Víkingsson, Arnór, Geirsson, Arni Jón, Steinsson, Kristján, van der Helm-van Mil, Annette H M

“…The susceptibility to rheumatoid arthritis (RA) is partly heritable, but whether the severity of RA is also influenced by genetics has not been determined. The…”
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Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis by Knevel, Rachel, Klein, Kerstin, Somers, Klaartje, Ospelt, Caroline, Houwing-Duistermaat, Jeanine J, van Nies, Jessica A B, de Rooy, Diederik P C, de Bock, Laura, Kurreeman, Fina A S, Schonkeren, Joris, Stoeken-Rijsbergen, Gerrie, Helmer, Quinta, van der Linden, Michael P M, Kern, Marlena, Manjarrez-Orduno, Nataly, Rodriguez-Rodriquez, Luis, Stinissen, Piet, Huizinga, Tom W J, Toes, Rene E M, Gay, Steffen, Gregersen, Peter K, Somers, Veerle, van der Helm-van Mil, Annette H M

“…Joint destruction is a hallmark of autoantibody-positive rheumatoid arthritis (RA), though the severity is highly variable between patients. The processes…”
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Population-based user-perceived experience of Rheumatic?: a novel digital symptom-checker in rheumatology by Lundberg, Karin, Qin, Ling, Aulin, Cecilia, van Spil, Willem Evert, Maurits, Marc P, Knevel, Rachel

“…ObjectiveDigital symptom-checkers (SCs) have potential to improve rheumatology triage and reduce diagnostic delays. In addition to being accurate, SCs should…”
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The ACPA recognition profile and subgrouping of ACPA-positive RA patients by Willemze, Annemiek, Böhringer, Stefan, Knevel, Rachel, Levarht, E W Nivine, Stoeken-Rijsbergen, Gerrie, Houwing-Duistermaat, Jeanine J, van der Helm-van Mil, Annette H M, Huizinga, Tom W J, Toes, René E M, Trouw, Leendert A

“…Anticitrullinated protein antibodies (ACPA) are the most predictive factor for the development of rheumatoid arthritis (RA). Epitope spreading towards more…”
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Defining erosive disease typical of RA in the light of the ACR/EULAR 2010 criteria for rheumatoid arthritis; results of the data driven phase by Knevel, Rachel, Lukas, Cédric, van der Heijde, Désirée, Rincheval, Nathalie, Combe, Bernard, van der Helm-van Mil, Annette H M

“…According to the 2010 criteria, rheumatoid arthritis (RA) can be classified in the presence of ≥6 points on the criteria or 'typical' erosive disease…”
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Rapid Response to Remdesivir in Hospitalised COVID-19 Patients: A Propensity Score Weighted Multicentre Cohort Study by Leegwater, Emiel, Dol, Lisa, Benard, Menno R., Roelofsen, Eveline E., Delfos, Nathalie M., van der Feltz, Machteld, Mollema, Femke P. N., Bosma, Liesbeth B. E., Visser, Loes E., Ottens, Thomas H., van Burgel, Nathalie D., Arbous, Sesmu M., El Bouazzaoui, Lahssan H., Knevel, Rachel, Groenwold, Rolf H. H., de Boer, Mark G. J., Visser, Leo G., Rosendaal, Frits R., Wilms, Erik B., van Nieuwkoop, Cees

“…Introduction Remdesivir is a registered treatment for hospitalised patients with COVID-19 that has moderate clinical effectiveness. Anecdotally, some patients’…”
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Rheumatic ?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study by Knevel, Rachel, Knitza, Johannes, Hensvold, Aase, Circiumaru, Alexandra, Bruce, Tor, Evans, Sebastian, Maarseveen, Tjardo, Maurits, Marc, Beaart-van de Voorde, Liesbeth, Simon, David, Kleyer, Arnd, Johannesson, Martina, Schett, Georg, Huizinga, Tom, Svanteson, Sofia, Lindfors, Alexandra, Klareskog, Lars, Catrina, Anca

“…Digital diagnostic decision support tools promise to accelerate diagnosis and increase health care efficiency in rheumatology. is an online tool developed by…”
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Development and validation of an early warning model for hospitalized COVID-19 patients: a multi-center retrospective cohort study by Smit, Jim M., Krijthe, Jesse H., Tintu, Andrei N., Endeman, Henrik, Ludikhuize, Jeroen, van Genderen, Michel E., Hassan, Shermarke, El Moussaoui, Rachida, Westerweel, Peter E., Goekoop, Robbert J., Waverijn, Geeke, Verheijen, Tim, den Hollander, Jan G., de Boer, Mark G. J., Gommers, Diederik A. M. P. J., van der Vlies, Robin, Schellings, Mark, Carels, Regina A., van Nieuwkoop, Cees, Arbous, Sesmu M., van Bommel, Jasper, Knevel, Rachel, de Rijke, Yolanda B., Reinders, Marcel J. T.

“…Background Timely identification of deteriorating COVID-19 patients is needed to guide changes in clinical management and admission to intensive care units…”
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From real-world electronic health record data to real-world results using artificial intelligence by Knevel, Rachel, Liao, Katherine P

“…With the worldwide digitalisation of medical records, electronic health records (EHRs) have become an increasingly important source of real-world data (RWD)…”
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Rheumatoid arthritis: 2014 treat-to-target RA recommendations--strategy is key by Huizinga, Tom, Knevel, Rachel

“…The treatment recommendations for rheumatoid arthritis (RA) have been updated. Among the changes included, rheumatologists are advised to share treatment…”
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