Search Results - "Knepper, Paul A"

Resting nailfold capillary blood flow in primary open-angle glaucoma by Cousins, Clara C, Chou, Jonathan C, Greenstein, Scott H, Brauner, Stacey C, Shen, Lucy Q, Turalba, Angela V, Houlihan, Patricia, Ritch, Robert, Wiggs, Janey L, Knepper, Paul A, Pasquale, Louis R

“…An altered haemodynamic profile for various ocular posterior segment capillary beds has been documented in primary open-angle glaucoma (POAG). POAG may also…”
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Nailfold Capillary Abnormalities in Primary Open-Angle Glaucoma: A Multisite Study by Pasquale, Louis R, Hanyuda, Akiko, Ren, Ai, Giovingo, Michael, Greenstein, Scott H, Cousins, Clara, Patrianakos, Thomas, Tanna, Angelo P, Wanderling, Christopher, Norkett, William, Wiggs, Janey L, Green, Kelsey, Kang, Jae H, Knepper, Paul A

“…There is considerable evidence for systemic vascular dysfunction in primary open-angle glaucoma (POAG). We performed nailfold capillary video microscopy to…”
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Nailfold Capillary Hemorrhages: Microvascular Risk Factors for Primary Open-Angle Glaucoma by Knepper, Paul A., Giovingo, Michael C., Kakouri, Agni, Bielskus, Indre E., Barry, Jordan L., Pfahler, Nicholas M., Volpe, Nicholas J.

“…Background. Primary open-angle glaucoma (POAG) is associated with systemic microvascular dysfunction including hemorrhages and other abnormalities of the…”
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Cross Talk Between TGF-β2 and TLR-4 by Knepper, Paul A

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The effect of various media and probe angles on the power output of the Cyclo G6 Glaucoma Laser System by Patel, Shyam, Kakouri, Agni, Chaudhary, Shweta, Knepper, Paul A., Pfahler, Nicholas M., Samples, John, Giovingo, Michael

“…To evaluate the effect of various media and Iridex MicroPulse P3 (MP3) probe angles on the power output from the Cyclo G6 Glaucoma Laser (G6) System. A laser…”
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Hypophosphorylation of Aqueous Humor sCD44 and Primary Open-Angle Glaucoma by Knepper, Paul A, Miller, Adam M, Choi, John, Wertz, Robert D, Nolan, Michael J, Goossens, William, Whitmer, Susan, Yue, Beatrice Y. J. T, Ritch, Robert, Liebmann, Jeffrey M, Allingham, R. Rand, Samples, John R

“…The ectodomain of CD44, the principal receptor for hyaluronic acid (HA), is shed as a 32-kDa fragment-soluble CD44 (sCD44)-which is cytotoxic to trabecular…”
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Effect of chondroitin sulfate on intraocular pressure in rats by Belforte, Nicolás, Sande, Pablo, de Zavalía, Nuria, Knepper, Paul A, Rosenstein, Ruth E

“…To study the effect of intracameral injections of chondroitin sulfate (CS) on intraocular pressure (IOP), retinal function, and histology in rats. Acute or…”
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sCD44 overexpression increases intraocular pressure and aqueous outflow resistance by Giovingo, Michael, Nolan, Michael, McCarty, Ryan, Pang, Iok-Hou, Clark, Abbot F, Beverley, Rachel M, Schwartz, Steven, Stamer, W Daniel, Walker, Loyal, Grybauskas, Algis, Skuran, Kevin, Kuprys, Paulius V, Yue, Beatrice Y J T, Knepper, Paul A

“…CD44 plays major roles in multiple physiologic processes. The ectodomain concentration of the CD44 receptor, soluble CD44 (sCD44), is significantly increased…”
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ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells by Grybauskas, Algis, Koga, Tomoyo, Kuprys, Paulius V, Nolan, Michael, McCarty, Ryan, Walker, Loyal, Green, Kelsey A, Norkett, William M, Yue, Beatrice Y J T, Knepper, Paul A

“…The aqueous humor nourishes the avascular tissues of the anterior segment, and the trabecular meshwork (TM) plays a role in the efflux of endogenous substances…”
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sCD44 internalization in human trabecular meshwork cells by Nolan, Michael J, Koga, Tomoyo, Walker, Loyal, McCarty, Ryan, Grybauskas, Algis, Giovingo, Michael C, Skuran, Kevin, Kuprys, Paulius V, Knepper, Paul A

“…To determine whether soluble CD44 (sCD44), a likely biomarker of primary open-angle glaucoma (POAG), is internalized in cultured human trabecular meshwork (TM)…”
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Lactate treatment causes NF-κB activation and CD44 shedding in cultured trabecular meshwork cells by MILLER, Adam M, NOLAN, Michael J, CHOI, John, KOGA, Tomoyo, XIANG SHEN, YUE, Beatrice Y. J. T, KNEPPER, Paul A

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Soluble CD44 Is Cytotoxic to Trabecular Meshwork and Retinal Ganglion Cells In Vitro by Choi, John, Miller, Adam M, Nolan, Michael J, Yue, Beatrice Y. J. T, Thotz, Susan T, Clark, Abbot F, Agarwal, Neeraj, Knepper, Paul A

“…Current glaucoma research targets neuroprotective therapies for retinal ganglion cells (RGCs) in primary open-angle glaucoma (POAG). The purpose of this study…”
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Aqueous Humor sCD44 Concentration and Visual Field Loss in Primary Open-angle Glaucoma by Nolan, Michael J, Giovingo, Michael C, Miller, Adam M, Wertz, Robert D, Ritch, Robert, Liebmann, Jeffrey M, Rand Allingham, R, Herndon, Leon W, Wax, Martin B, Smolyak, Regina, Hasan, Fareed, Barnett, Edward M, Samples, John R, Knepper, Paul A

“…PURPOSETo correlate aqueous humor soluble CD44 (sCD44) concentration, visual field loss, and glaucoma risk factors in primary open-angle glaucoma (POAG)…”
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The Presence of Transcription Factors in Chicken Albumin, Yolk and Blastoderm by Paul A. Knepper, Chandra S. K. Mayanil, Erin Hayes, William Goossens, Byrne, Richard W., David G. Mc Lone

“…Embryonic development is determined by preset intrinsic programs and extrinsic signals. To explore the possibility that transcription factors are present at…”
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The Presence of Transcription Factors in Fetal Bovine Sera by Knepper, P A, Mayanil, C S, Goossens, W, McLone, D C, Hayes, E

“…Three sources of fetal bovine serum (FBS) were fractionated by ammonium sulfate precipitation and by sodium dodecyl sulfate-polyacrylamide gel electrophoresis…”
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Reconstitution of Trabecular Meshwork GAGs: Influence of Hyaluronic Acid and Chondroitin Sulfate on Flow Rates by Knepper, Paul A, Fadel, James R, Miller, Adam M, Goossens, William, Choi, John, Nolan, Michael J, Whitmer, Susan

“…PURPOSE:This study was undertaken to determine whether the concentration of hyaluronic acid (HA) and of chondroitin sulfate (CS) occurring in the normal and…”
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Ultrastructural studies of primary congenital glaucoma in rabbits by Knepper, P A, Goossens, W, McLone, D G

“…The cause of congenital glaucoma is unknown. To determine whether the site of impaired aqueous outflow is the entrance to the trabecular meshwork (TM), within…”
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Consensus recommendations for trabecular meshwork cell isolation, characterization and culture by Keller, Kate E., Bhattacharya, Sanjoy K., Borrás, Theresa, Brunner, Thomas M., Chansangpetch, Sunee, Clark, Abbott F., Dismuke, W. Michael, Du, Yiqin, Elliott, Michael H., Ethier, C. Ross, Faralli, Jennifer A., Freddo, Thomas F., Fuchshofer, Rudolf, Giovingo, Michael, Gong, Haiyan, Gonzalez, Pedro, Huang, Alex, Johnstone, Murray A., Kaufman, Paul L., Kelley, Mary J., Knepper, Paul A., Kopczynski, Casey C., Kuchtey, John G., Kuchtey, Rachel W., Kuehn, Markus H., Lieberman, Raquel L., Lin, Shan C., Liton, Paloma, Liu, Yutao, Lütjen-Drecoll, Elke, Mao, Weiming, Masis-Solano, Marisse, McDonnell, Fiona, McDowell, Colleen M., Overby, Darryl R., Pattabiraman, Padmanabhan P., Raghunathan, Vijay K., Rao, P. Vasanth, Rhee, Douglas J., Chowdhury, Uttio Roy, Russell, Paul, Samples, John R., Schwartz, Donald, Stubbs, Evan B., Tamm, Ernst R., Tan, James C., Toris, Carol B., Torrejon, Karen Y., Vranka, Janice A., Wirtz, Mary K., Yorio, Thomas, Zhang, Jie, Zode, Gulab S., Fautsch, Michael P., Peters, Donna M., Acott, Ted S., Stamer, W. Daniel

“…Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular mechanisms involved in the regulation of conventional outflow…”
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The cause of Chiari II malformation: a unified theory by McLone, D G, Knepper, P A

“…The cause of the Chiari II hindbrain deformity in children born with a myelomeningocele can be explained by the lack of distention of the embryonic ventricular…”
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Ocular Hypotensive and Aqueous Outflow-enhancing Effects of AL-3037A (Sodium Ferri Ethylenediaminetetraacetate) by Pang, Iok-Hou, Moll, Hans, McLaughlin, Marsha A, Knepper, Paul A, De Santis, Louis, Epstein, David L, Clark, Abbot F

“…AL-3037A (Sodium ferri ethylenediaminetetraacetate), a novel compound shown to stimulate the degradation of glycosaminoglycans, was evaluated for its effects…”
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