Search Results - "Knaus, William A."

Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012 by Zimmerman, Jack E, Kramer, Andrew A, Knaus, William A

“…A decrease in disease-specific mortality over the last twenty years has been reported for patients admitted to United States (US) hospitals, but data for…”
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Impact of Patient Distance to Radiation Therapy on Mastectomy Use in Early-Stage Breast Cancer Patients by SCHROEN, Anneke T, BRENIN, David R, KELLY, Maria D, KNAUS, William A, SLINGLUFF, Craig L

“…Treatment access underlies quality cancer care. We hypothesize that mastectomy rates in a rural state are independently influenced by distance to radiation…”
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All Public Health is Local: Lessons From Eagle County During the First 2 Years of the Coronavirus Disease-2019 Pandemic by Knaus, William A., Kehoe, Shaneis, Lindley, Chris

“…BACKGROUNDDuring the coronavirus disease-2019 (COVID-19) pandemic cumulative United States COVID-19 deaths per capita were higher than all other large,…”
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What Do Women Know About Breast Density? Results From a Population Survey of Virginia Women by Guterbock, Thomas M., PhD, Cohn, Wendy F., PhD, Rexrode, Deborah L., PhD, Eggleston, Casey M., PhD, Dean-McKinney, Melissa, RN, Novicoff, Wendy M., PhD, Yaffe, Martin J., PhD, Knaus, William A., MD, Harvey, Jennifer A., MD

“…Abstract Purpose Breast density reduces the sensitivity of mammography and is a moderate independent risk factor for breast cancer. Virginia is one of 24…”
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New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research by Knaus, William A, Marks, Richard D

“…In this issue of JAMA, Seymour and his multidisciplinary team of coauthors aim to improve the current understanding of sepsis by identifying new clinical…”
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Severity of Illness and Predictive Models in Society of Critical Care Medicine’s First 50 Years: A Tale of Concord and Conflict by Kramer, Andrew A., Zimmerman, Jack E., Knaus, William A.

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Prognostic Modeling and Major Dataset Shifts During the COVID-19 Pandemic: What Have We Learned for the Next Pandemic? by Knaus, William A.

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Relemed: sentence-level search engine with relevance score for the MEDLINE database of biomedical articles by Siadaty, Mir S, Shu, Jianfen, Knaus, William A

“…Receiving extraneous articles in response to a query submitted to MEDLINE/PubMed is common. When submitting a multi-word query (which is the majority of…”
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Evaluation of Acute Physiology and Chronic Health Evaluation III predictions of hospital mortality in an independent database by Zimmerman, Jack E, Wagner, Douglas P, Draper, Elizabeth A, Wright, Leslie, Alzola, Carlos, Knaus, William A

“…OBJECTIVETo assess the accuracy and validity of Acute Physiology and Chronic Health Evaluation (APACHE) III hospital mortality predictions in an independent…”
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Outcomes up to 5 years after severe, acute respiratory failure by Garland, Allan, Dawson, Neal V, Altmann, Irene, Thomas, Charles L, Phillips, Russell S, Tsevat, Joel, Desbiens, Norman A, Bellamy, Paul E, Knaus, William A, Connors, Jr, Alfred F

“…To use an existing database from a large cohort study with follow-up as long as 5.5 years to assess the extended prognosis of patients who survived their…”
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A Case-Control Study to Add Volumetric or Clinical Mammographic Density into the Tyrer-Cuzick Breast Cancer Risk Model by Brentnall, Adam R, Cohn, Wendy F, Knaus, William A, Yaffe, Martin J, Cuzick, Jack, Harvey, Jennifer A

“…Accurate breast cancer risk assessment for women attending routine screening is needed to guide screening and preventive interventions. We evaluated the…”
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Locating previously unknown patterns in data-mining results: a dual data- and knowledge-mining method by Siadaty, Mir S, Knaus, William A

“…Data mining can be utilized to automate analysis of substantial amounts of data produced in many organizations. However, data mining produces large numbers of…”
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The Acute Physiology and Chronic Health Evaluation II article of Knaus et al with expert commentary by Dr Derek Angus by Al-Khafaji, Ali, MD, MPH, Angus, Derek C., MD, MPH, Knaus, William A., MD

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Initial clinical validation of Health Heritage, a patient-facing tool for personal and family history collection and cancer risk assessment by Baumgart, Leigh A., Postula, Kristen J. Vogel, Knaus, William A.

“…Personal and family health histories remain important independent risk factors for cancer; however they are currently not being well collected or used…”
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Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects by Simonds, Naoko I, Khoury, Muin J, Schully, Sheri D, Armstrong, Katrina, Cohn, Wendy F, Fenstermacher, David A, Ginsburg, Geoffrey S, Goddard, Katrina A B, Knaus, William A, Lyman, Gary H, Ramsey, Scott D, Xu, Jianfeng, Freedman, Andrew N

“…A major promise of genomic research is information that can transform health care and public health through earlier diagnosis, more effective prevention and…”
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Data mining and clinical data repositories: Insights from a 667,000 patient data set by Mullins, Irene M., Siadaty, Mir S., Lyman, Jason, Scully, Ken, Garrett, Carleton T., Greg Miller, W., Muller, Rudy, Robson, Barry, Apte, Chid, Weiss, Sholom, Rigoutsos, Isidore, Platt, Daniel, Cohen, Simona, Knaus, William A.

“…Clinical repositories containing large amounts of biological, clinical, and administrative data are increasingly becoming available as health care systems…”
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CXC chemokine receptor 3 expression by activated CD8+ T cells is associated with survival in melanoma patients with stage III disease by MULLINS, Irene M, SLINGLUFF, Craig L, LEE, Jae K, GARBEE, Courtney F, JIANFEN SHU, ANDERSON, Sara G, MAYER, Melanie E, KNAUS, William A, MULLINS, David W

“…Despite the presence of tumor Ag-specific CD8(+) T cells in the peripheral blood, metastatic melanoma often evades immune-mediated destruction. Even after…”
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Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research by Goddard, Katrina A.B., Knaus, William A., Whitlock, Evelyn, Lyman, Gary H., Feigelson, Heather Spencer, Schully, Sheri D., Ramsey, Scott, Tunis, Sean, Freedman, Andrew N., Khoury, Muin J., Veenstra, David L.

“…The clinical utility is uncertain for many cancer genomic applications. Comparative effectiveness research (CER) can provide evidence to clarify this…”
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Hospital and 1-Year Survival of Patients Admitted to Intensive Care Units With Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Seneff, Michael G, Wagner, Douglas P, Wagner, Randall P, Zimmerman, Jack E, Knaus, William A

“…Objective.—To describe outcomes and identify variables associated with hospital and 1-year survival for patients admitted to an intensive care unit (ICU) with…”
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GeneX Va: VBC open source microarray database and analysis software by Lee, Jae K, Laudeman, Tom, Kanter, Jodi, James, Teela, Siadaty, Mir S, Knaus, William A, Prorok, Alyson, Bao, Yongde, Freeman, Brad, Puiu, Daniela, Wen, Li Min, Buck, Gregory A, Schlauch, Karen, Weller, Jennifer, Fox, Jay W

“…Developed by the Virginia Bioinformatics Consortium (VBC), GeneX Va is an open source, freeware database and bioinformatics analysis software for archiving and…”
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