Search Results - "Knaus, H."
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Containment of a traceable COVID-19 outbreak among healthcare workers at a hematopoietic stem cell transplantation unit
Published in Bone marrow transplantation (Basingstoke) (01-07-2020)Get full text
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Cerebellar Ataxia and Purkinje Cell Dysfunction Caused by Ca2+-Activated K+Channel Deficiency
Published in Proceedings of the National Academy of Sciences - PNAS (22-06-2004)“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
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rKv1.2 overexpression in the central medial thalamic area decreases caffeine‐induced arousal
Published in Genes, brain and behavior (01-11-2011)“…The voltage‐gated potassium channel Kv1.2 belongs to the shaker‐related family and has recently been implicated in the control of sleep profile on the basis of…”
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An Endoplasmic Reticulum Trafficking Signal Prevents Surface Expression of a Voltage- and Ca2+-Activated K+ Channel Splice Variant
Published in Proceedings of the National Academy of Sciences - PNAS (06-07-2004)“…Protein delivery to restricted plasma membrane domains is exquisitely regulated at different stages of the cell trafficking machinery. Traffic control involves…”
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Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca2+ -activated K+ channel
Published in Neuroscience (15-06-2007)“…Abstract Large conductance voltage and calcium-activated K+ channels play critical roles in neuronal excitability and vascular tone. Previously, we showed that…”
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A Phase I Trial of Ipilimumab (IPI) in Patients (PTS) with Myelodysplastic Syndromes (MDS) after Hypomethylating Agent (HMAS) Failure
Published in Leukemia research (01-04-2017)Get full text
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Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons
Published in Cell death & disease (16-01-2014)Get full text
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Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca(2+)-activated K+ channel
Published in Neuroscience (15-06-2007)“…Large conductance voltage and calcium-activated K(+) channels play critical roles in neuronal excitability and vascular tone. Previously, we showed that…”
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Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals
Published in The Journal of neuroscience (01-02-1996)“…Tissue expression and distribution of the high-conductance Ca(2+)-activated K+ channel Slo was investigated in rat brain by immunocytochemistry, in situ…”
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Presynaptic Ca2+-Activated K+ Channels in Glutamatergic Hippocampal Terminals and Their Role in Spike Repolarization and Regulation of Transmitter Release
Published in The Journal of neuroscience (15-12-2001)“…Large-conductance Ca(2+)-activated K(+) channels (BK, also called Maxi-K or Slo channels) are widespread in the vertebrate nervous system, but their functional…”
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Measurements of burr-hole localization for endoscopic procedures in the third ventricle in children
Published in Child's nervous system (01-03-2009)“…Objective In a retrospective study, we measured the localization for the burr hole for neuroendoscopic procedures in the third ventricle, which are determined…”
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High affinity interaction of mibefradil with voltage‐gated calcium and sodium channels
Published in British journal of pharmacology (01-06-2000)“…Mibefradil is a novel Ca2+ antagonist which blocks both high‐voltage activated and low voltage‐activated Ca2+ channels. Although L‐type Ca2+ channel block was…”
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Subunit composition of brain voltage-gated potassium channels determined by hongotoxin-1, novel peptide derived from Centruroides limbatus venom
Published in The Journal of biological chemistry (30-01-1998)“…Five novel peptidyl inhibitors of Shaker-type (Kv1) K+ channels have been purified to homogeneity from venom of the scorpion Centruroides limbatus. The…”
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Purification and reconstitution of the high-conductance, calcium-activated potassium channel from tracheal smooth muscle
Published in The Journal of biological chemistry (07-01-1994)“…The high-conductance Ca(2+)-activated K+ (maxi-K) channel from bovine tracheal smooth muscle was purified to apparent homogeneity by a combination of…”
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Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels
Published in The Journal of biological chemistry (11-02-1994)“…High conductance Ca(2+)-activated K+ (maxi-K) channels from bovine tracheal and aortic smooth muscle membranes have been purified employing monoiodotyrosine…”
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Increased Expression of Ca2+ -Sensitive K+ Channels in Aorta of Hypertensive Rats
Published in Hypertension (Dallas, Tex. 1979) (01-12-1997)“…Potassium efflux through Ca -sensitive K channels (KCa channels) is increased in arterial smooth muscle cells from hypertensive rats, but the molecular…”
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Increased Expression of Ca2+-Sensitive K+ Channels in the Cerebral Microcirculation of Genetically Hypertensive Rats: Evidence for Their Protection Against Cerebral Vasospasm
Published in Circulation research (06-04-1998)“…The Ca K channel (KCa channel) plays a key role in buffering pressure-induced constriction of small cerebral arteries. An amplified current through this…”
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Tremorgenic Indole Alkaloids Potently Inhibit Smooth Muscle High-Conductance Calcium-Activated Potassium Channels
Published in Biochemistry (Easton) (17-05-1994)“…Tremorgenic indole alkaloids produce neurological disorders (e.g., staggers syndromes) in ruminants. The mode of action of these fungal mycotoxins is not…”
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Purification, Molecular Cloning, and Expression of the Mammalian sigma1-Binding Site
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-1996)“…Sigma-ligands comprise several chemically unrelated drugs such as haloperidol, pentazocine, and ditolyl-guanidine, which bind to a family of low molecular mass…”
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