Search Results - "Knauer, Daniel J"

Circulating Serologic and Molecular Biomarkers in Malignant Melanoma by Palmer, Shanique R., MBBS, Erickson, Lori A., MD, Ichetovkin, Ilia, PhD, Knauer, Daniel J., PhD, Markovic, Svetomir N., MD, PhD

“…Abstract The worldwide incidence of malignant melanoma has been increasing during the past decade and is a public health concern because this disease accounts…”
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Antibody-targeted paclitaxel loaded nanoparticles for the treatment of CD20+ B-cell lymphoma by Nevala, Wendy K., Butterfield, John T., Sutor, Shari L., Knauer, Daniel J., Markovic, Svetomir N.

“…We developed a nano-antibody targeted chemotherapy (nATC) delivery strategy in which tumor specific and clinically relevant antibodies (rituximab, anti-CD20)…”
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Identification of a peptide-peptide binding motif in the coating of nab-paclitaxel nanoparticles with clinical antibodies: bevacizumab, rituximab, and trastuzumab by Butterfield, John T., Kim, Hidong, Knauer, Daniel J., Nevala, Wendy K., Markovic, Svetomir N.

“…Antibody directed chemotherapy (ADC) takes advantage of the selectivity of the monoclonal antibody to increase the efficacy of the chemotherapeutic agent,…”
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Antibody-Targeted Chemotherapy for the Treatment of Melanoma by Nevala, Wendy K, Buhrow, Sarah A, Knauer, Daniel J, Reid, Joel M, Atanasova, Elena A, Markovic, Svetomir N

“…Antibody-directed chemotherapy (ADC) offers an advantage over conventional chemotherapy because it provides antibody-directed targeting, with resultant…”
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All Three LDL Receptor Homology Regions of the LDL Receptor-Related Protein Bind Multiple Ligands by Croy, Johnny E, Shin, William D, Knauer, Mary F, Knauer, Daniel J, Komives, Elizabeth A

“…The three complete human LDL receptor homology regions of the LDL receptor-related protein (sLRP2, sLRP3, and sLRP4) have been expressed in Pichia pastoris…”
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Correction: Antibody-Targeted Chemotherapy for the Treatment of Melanoma by Nevala, Wendy K, Buhrow, Sarah A, Knauer, Daniel J, Reid, Joel M, Atanasova, Elena A, Markovic, Svetomir N

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Protease Nexin 1 Is a Potent Urinary Plasminogen Activator Inhibitor in the Presence of Collagen Type IV by Crisp, Robert J., Knauer, Mary F., Knauer, Daniel J.

“…Protease nexin 1 (PN1) in solution forms inhibitory complexes with thrombin or urokinase, which have opposing effects on the blood coagulation cascade. An…”
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The Efficient Catabolism of Thrombin-Protease Nexin 1 Complexes Is a Synergistic Mechanism That Requires Both the LDL Receptor-related Protein and Cell Surface Heparins by Knauer, Mary F., Kridel, Steven J., Hawley, Stephen B., Knauer, Daniel J.

“…Protease nexin 1 (PN1) is a serine protease inhibitor (SERPIN) that acts as a suicide substrate for thrombin (Th) and urokinase-type plasminogen activator…”
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Identification of a Binding Site in Protease Nexin I (PN1) Required for the Receptor Mediated Internalization of PN1-Thrombin Complexes by Knauer, M F, Hawley, S B, Knauer, D J

“…An overlapping synthetic peptide library was constructed representing most of the mature protease nexin I (PN1) sequence from the amino terminus to the…”
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Roles of the Heparin and Low Density Lipid Receptor-related Protein-binding Sites of Protease Nexin 1 (PN1) in Urokinase-PN1 Complex Catabolism by Crisp, Robert J., Knauer, Daniel J., Knauer, Mary F.

“…We have previously described thrombin (Th)-protease nexin 1 (PN1) inhibitory complex binding to cell surface heparins and subsequent low density lipid…”
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Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III by Kridel, Steven J., Chan, William W., Knauer, Daniel J.

“…Variant forms of human antithrombin III with glutamine or threonine substitutions at Lys114, Lys125, Lys133, Lys136, and Lys139 were expressed in insect cells…”
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SERPIN Regulation of Factor XIa by Knauer, Daniel J., Majumdar, Devdoot, Fong, Pei-Chieh, Knauer, Mary F.

“…In the present studies we have made the novel observation that protease nexin 1 (PN1), a member of theserine protease inhibitor (SERPIN) superfamily, is a…”
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Lysine Residue 114 in Human Antithrombin III Is Required for Heparin Pentasaccharide-mediated Activation by Kridel, Steven J., Knauer, Daniel J.

“…Recombinant native antithrombin III (ATIII) and two genetic variants with glutamine substitutions at lysine residues 114 and 139 were expressed in insect cells…”
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Epidermal growth factor receptor immunoreactivity in rat brain. Development and cellular localization by Gómez-Pinilla, F, Knauer, D J, Nieto-Sampedro, M

“…In rat brain, distinct epidermal growth factor-receptor immunoreactivity (EGFR-IR) first appeared in astroglia at about day 16 postnatal, reached maximum…”
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Analysis of a Structural Determinant in Thrombin-Protease Nexin 1 Complexes That Mediates Clearance by the Low Density Lipoprotein Receptor-related Protein by Knauer, Mary F., Crisp, Robert J., Kridel, Steven J., Knauer, Daniel J.

“…We recently identified a synthetic peptide, Pro47–Ile58, derived from the mature protease nexin 1 (PN1) sequence, that inhibited the low density lipoprotein…”
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Longitudinal Examination of Contextual Risk, Promotive Factors, and Psychosocial Functioning Using Structural Equation Modeling with a Sample of Serious Adolescent Offenders by Knauer, Daniel J

“…Mental health problems, including substance use problems, are more prevalent among adolescent criminal offenders than among the general population and are…”
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Epidermal Growth Factor Immunoreactive Material in the Central Nervous System: Location and Development by Fallon, James H., Seroogy, Kim B., Loughlin, Sandra E., Morrison, Richard S., Bradshaw, Ralph A., Knauer, Daniel J., Cunningham, Dennis D.

“…Epidermal growth factor (EGF) is a potent mitogen with hormonal activity in the gastrointestinal tract. Material cross-reacting with EGF was detected in the…”
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Heparin binding domain of antithrombin III: characterization using a synthetic peptide directed polyclonal antibody by Smith, Jeffrey W, Dey, Nabina, Knauer, Daniel J

“…Antithrombin III (ATIII) is a plasma-borne serine protease inhibitor that apparently forms covalent complexes with thrombin. The interaction between ATIII and…”
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Perceived racial microaggressions and psychological well-being among African American college students by Knauer, Daniel J

“…The purpose of this study was to examine the relationships among perceived racial microaggressions, social support, and indicators of psychological well-being…”
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P3-307 Identification of a domain in the amyloid precursor protein (APP) required for the LRP-mediated endocytosis of APP: protease complexes by Knauer, Mary F., Fouts, David A., Knauer, Daniel J.

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