Search Results - "Knapp, Maura"

Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction by Shimizu, Toru, Narang, Nikhil, Chen, Phetcharat, Yu, Brian, Knapp, Maura, Janardanan, Jyothi, Blair, John, Liao, James K

“…Although left ventricular (LV) diastolic dysfunction is often associated with hypertension, little is known regarding its underlying pathophysiological…”
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Endothelial Aryl Hydrocarbon Receptor Nuclear Translocator Mediates the Angiogenic Response to Peripheral Ischemia in Mice With Type 2 Diabetes Mellitus by Nguyen, Tu, Zheng, Mei, Knapp, Maura, Sladojevic, Nikola, Zhang, Qin, Ai, Lizhuo, Harrison, Devin, Chen, Anna, Sitikov, Albert, Shen, Le, Gonzalez, Frank J, Zhao, Qiong, Fang, Yun, Liao, James J K, Wu, Rongxue

“…Hypoxia-inducible factors (HIFs) are the master regulators of angiogenesis, a process that is impaired in patients with diabetes mellitus (DM). The…”
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Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy by Knapp, Maura, Tu, Xin, Wu, Rongxue

“…Diabetes mellitus is currently a major public health problem. A common complication of diabetes is cardiac dysfunction, which is recognized as a microvascular…”
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Abstract 9717: Reduction in Arnt/hif1 Beta Mediates Vascular Dysfunction in Mice with Type 2 Diabetes Mellitus by Wu, Rongxue, Nguyen, Tu, Zheng, Mei, Knapp, Maura, Sladojevic, Nikola, Sitikov, Albert, Liao, James K, Wu, Rongxue

“…IntroductionEndothelial dysfunction, especially at the microvasculature level, is one of the most deleterious events in diabetes. ARNT is a transcription…”
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Loss of ARNT in Endothelial Cells Mediated Inflammation Pathway Promotes Diabetic Cardiac Vascular Dysfunction by Rajasekaran, Snekha, Zheng, Mei, Knapp, Maura, Ullah, Karim, Zhang, Qin, Li, Yan, Su, Qiaozhu, Liao, James K., Zhao, Qiong, Wu, Rongxue

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Abstract 552: Bradykinin Receptor B1/ Matrix Metalloprotease 3 Pathway is a Novel Target in Preventing Cardiac Ischemia-reperfusion Injury by Zhang, Qin, Ai, Lizhuo, Liu, Lifeng, Betancourt, Cristian, Knapp, Maura, Sitikov, Albert, Sharp, Willard W, Liao, James K, Wu, Rongxue

“…Abstract only Introduction: Impaired endothelial function leads to the progression of heart failure after Ischemia-reperfusion (IR). Kinin activation of…”
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Abstract MP250: Reduction In Endothelial Aryl Hydrocarbon Receptor Nuclear Translocator (arnt) Mediates Vascular Dysfunction In Mice With Type 2 Diabetes Mellitus by Nguyen, Tu, Pan, Kaichao, Knapp, Maura, Zheng, Mei, Sladojevic, Nikola, Ai, Lizhuo, Sitikov, Albert, Gonzalez, Frank, Liao, james K, Wu, Rongxue

“…BackgroundEndothelial dysfunction, especially at the microvasculature level, is one of the most deleterious events in diabetes. ARNT is a transcription factor…”
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Abstract 63: Reduction in Glucocorticoid Receptor Expression Attenuates Pressure Overload-induced Cardiac Hypertrophy and Promotes Heart Failure in Mice by Wu, Rongxue, Knapp, Maura, Zheng, Mei, Liao, James K

“…Abstract only Background: Left ventricular hypertrophy (LVH) is an independent risk factor for heart failure and sudden death. In addition, LVH is also a…”
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Abstract 45: Endothelial Aryl Hydrocarbon Receptor Nucleatranslator (Arnt) is a Novel Regulator of Cardiac Endothelial Barrier Integrity in Diabetes by Knapp, Maura, Zheng, Mei, Sladojevic, Nikola, Zhao, Qiong, Birukov, Konstaintin G, Liao, James K, Wu, Rongxue

“…Abstract only Background: Diabetes leads to endothelial barrier dysfunction and altered endothelial permeability, which results in increased cardiovascular…”
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Abstract 392: Decreased ARNT Mediates Cardiovascular Endothelial Dysfunction in Diabetic Cardiomyopathy by Knapp, Maura, Zheng, Mei, Huang, Hao, Liao, James K, Wu, Rongxue

“…Abstract only Background: Endothelial dysfunction is thought to be one of the key risk factors leading to cardiac dysfunction. We have previously shown that…”
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Abstract 17332: Endothelial-Specific Deletion of Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Leads to Microvascular Barrier Dysfunction and Cardiomyopathy by Knapp, Maura, Zheng, Mei, Stikov, Alik, Sladojevic, Nikola, Chen, Anna, Birukov, Konstantin G, Zhao, Qiong, Patel, Amit, Liao, James K, Wu, Rongxue

“…IntroductionCardiac microvascular hyperpermeability is a key contributor to heart disease in patients with diabetes. Although the link between diabetes and…”
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Abstract 306: Endothelial Arnt Mediates Cardiac Remodeling After Ischemia Reperfusion Injury Through an MMP Pathway by Zheng, Mei, Knapp, Maura, Sladojevic, Nikola, Chen, Anna, Andrade, Jorge, Zhao, Qiong, Liao, James K, Wu, Rongxue

“…Abstract only Background: Prevention of myocardial injury following heart attack is a challenge due to lack of effective treatments and the potential to…”
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Abstract 101: Endothelial Arnt Regulates Microvascular Endothelial Barrier Function in Heart Failure Through a Novel Mmp3 Pathway by Zheng, Mei, Knapp, Maura, Andrade, Jorge, Cheng, Anna, Sladojevic, Nikola, Birukov, Konstantin G, Zhao, Qiong, liao, James K., Wu, Rongxue (Rosie)

“…Abstract only Background: Increased microvascular permeability and cardiac interstitial edema formation are major contributors to progressive myocyte…”
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Abstract 20699: Reduction of Endothelial Arnt Mediates Vascular Dysfunction in Diabetes by Knapp, Maura, Zheng, Mei, Sladojevic, Nikola, Zhao, Qiong, Liao, James K, Wu, Rongxue

“…IntroductionEndothelial dysfunction, a central hallmark of diabetes, predisposes diabetic patients to a number of cardiovascular complications. We have…”
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