Search Results - "Knapp, Jason"

Murine Mast Cells That Are Deficient in IFNAR-Signaling Respond to Viral Infection by Producing a Large Amount of Inflammatory Cytokines, a Low Level of Reactive Oxygen Species, and a High Rate of Cell Death by Mehrani, Yeganeh, Knapp, Jason P, Kakish, Julia E, Tieu, Sophie, Javadi, Helia, Chan, Lily, Stegelmeier, Ashley A, Napoleoni, Christina, Bridle, Byram W, Karimi, Khalil

“…Mat cells (MCs) are located in the skin and mucous membranes at points where the body meets the environment. When activated, MCs release inflammatory…”
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Tumor Temperature: Friend or Foe of Virus-Based Cancer Immunotherapy by Knapp, Jason P, Kakish, Julia E, Bridle, Byram W, Speicher, David J

“…The temperature of a solid tumor is often dissimilar to baseline body temperature and, compared to healthy tissues, may be elevated, reduced, or a mix of both…”
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Investigating the effect of reduced temperatures on the efficacy of rhabdovirus-based viral vector platforms by Kakish, Julia E, Mehrani, Yeganeh, Kodeeswaran, Arthane, Geronimo, Katrina, Clark, Mary Ellen, van Vloten, Jacob P, Karimi, Khalil, Mallard, Bonnie A, Meng, Baozhong, Bridle, Byram W, Knapp, Jason P

“…Rhabdoviral vectors can induce lysis of cancer cells. While studied almost exclusively at 37 °C, viruses are subject to a range of temperatures , including…”
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Cytokine Storm Syndrome in SARS-CoV-2 Infections: A Functional Role of Mast Cells by Hafezi, Bahareh, Chan, Lily, Knapp, Jason P, Karimi, Negar, Alizadeh, Kimia, Mehrani, Yeganeh, Bridle, Byram W, Karimi, Khalil

“…Cytokine storm syndrome is a cascade of escalated immune responses disposing the immune system to exhaustion, which might ultimately result in organ failure…”
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Tumour vasculature: Friend or foe of oncolytic viruses? by Santry, Lisa A., van Vloten, Jacob P., Knapp, Jason P., Matuszewska, Kathy, McAusland, Thomas M., Minott, Jessica A., Mould, Robert C., Stegelmeier, Ashley A., Major, Pierre P., Wootton, Sarah K., Petrik, James J., Bridle, Byram W.

“…In the past two decades there have been substantial advances in understanding the anti-cancer mechanisms of oncolytic viruses (OVs). OVs can mediate their…”
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Characterisation and Sensitivity of a Canine Mast Cell Tumour Line to Oncolytic Viruses by Mehrani, Yeganeh, Kakish, Julia E., Napoleoni, Christina, Thompson, Jennifer Jane, Knapp, Jason P., Minott, Jessica A., Yates, Jacob G. E., Stuart, Deirdre, Coomber, Brenda L., Foster, Robert A., Bridle, Byram W., Karimi, Khalil

“…Canine mast cell tumours (MCTs) are one of the most common skin cancers of dogs. Surgical removal is the primary treatment, but recurrence and metastasis can…”
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Review of Influenza Virus Vaccines: The Qualitative Nature of Immune Responses to Infection and Vaccination Is a Critical Consideration by Chan, Lily, Alizadeh, Kasra, Alizadeh, Kimia, Fazel, Fatemeh, Kakish, Julia E., Karimi, Negar, Knapp, Jason P., Mehrani, Yeganeh, Minott, Jessica A., Morovati, Solmaz, Rghei, Amira, Stegelmeier, Ashley A., Vanderkamp, Sierra, Karimi, Khalil, Bridle, Byram W.

“…Influenza viruses have affected the world for over a century, causing multiple pandemics. Throughout the years, many prophylactic vaccines have been developed…”
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Optimal Expression, Function, and Immunogenicity of an HIV-1 Vaccine Derived from the Approved Ebola Vaccine, rVSV-ZEBOV by Azizi, Hiva, Knapp, Jason P, Li, Yue, Berger, Alice, Lafrance, Marc-Alexandre, Pedersen, Jannie, de la Vega, Marc-Antoine, Racine, Trina, Kang, Chil-Yong, Mann, Jamie F S, Dikeakos, Jimmy D, Kobinger, Gary, Arts, Eric J

“…Vesicular stomatitis virus (VSV) remains an attractive platform for a potential HIV-1 vaccine but hurdles remain, such as selection of a highly immunogenic…”
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Intranasal vaccination with a Newcastle disease virus-vectored vaccine protects hamsters from SARS-CoV-2 infection and disease by Warner, Bryce M., Santry, Lisa A., Leacy, Alexander, Chan, Mable, Pham, Phuc H., Vendramelli, Robert, Pei, Yanlong, Tailor, Nikesh, Valcourt, Emelissa, Leung, Anders, He, Shihua, Griffin, Bryan D., Audet, Jonathan, Willman, Marnie, Tierney, Kevin, Albietz, Alixandra, Frost, Kathy L., Yates, Jacob G.E., Mould, Robert C., Chan, Lily, Mehrani, Yeganeh, Knapp, Jason P., Minott, Jessica A., Banadyga, Logan, Safronetz, David, Wood, Heidi, Booth, Stephanie, Major, Pierre P., Bridle, Byram W., Susta, Leonardo, Kobasa, Darwyn, Wootton, Sarah K.

“…The pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19). Worldwide efforts are being made…”
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Radiographic, Push-out and Confocal Comparison of RootEnd Fillings with BC Root Repair Material Alone or Combined with BC Sealer Using Two Different Placement Techniques with and without Pretreatment with EDTA by Knapp, Jason

“…OBJECTIVE: This study aimed to determine if EDTA pretreatment or addition of sealer before application of putty effects root-end filling quality.MATERIALS AND…”
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Efficacy of root-end filling techniques using premixed putty type bioceramic cements: an ex vivo study by Knapp, Jason, Kirkpatrick, Timothy, Ontiveros, Joe C., Jaramillo, David E., Kim, Hyeon-Cheol, Jeong, Ji Wook

“…Objectives Currently, premixed putty-type bioceramic cements (PPBCs) have become popular materials for root-end fillings. This study investigated three…”
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Enhancement of CD4 Binding, Host Cell Entry, and Sensitivity to CD4bs Antibody Inhibition Conferred by a Natural but Rare Polymorphism in the HIV-1 Envelope by Ratcliff, Annette N, Venner, Colin M, Olabode, Abayomi S, Knapp, Jason, Pankrac, Joshua, Derecichei, Iulian, Gibson, Richard M, Finzi, Andrés, Li, Yue, Mann, Jamie F S, Arts, Eric J

“…A rare but natural polymorphism in the HIV-1 envelope (Env) glycoprotein, lysine at position 425 was selected as a mutation conferring resistance to maraviroc…”
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Designing an Optimal HIV-1 Env Immunogen for the Vesicular Stomatitis Virus Vaccine Platform and Elucidating the Role of HIV-1 Nef in Env Traffickingl by Knapp, Jason

“…Current vesicular stomatitis virus (VSV)-based HIV vaccines require an optimal HIV envelope immunogen to improve protection in vivo. Furthermore, the…”
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A heterogeneous human immunodeficiency virus-like particle (VLP) formulation produced by a novel vector system by Pankrac, Joshua, Klein, Katja, McKay, Paul F., King, Deborah F. L., Bain, Katie, Knapp, Jason, Biru, Tsigereda, Wijewardhana, Chanuka N., Pawa, Rahul, Canaday, David H., Gao, Yong, Fidler, Sarah, Shattock, Robin J., Arts, Eric J., Mann, Jamie F. S.

“…First identified as the etiological agent behind Acquired Immunodeficiency Syndrome (AIDS) in the early 1980s, HIV-1 has continued to spread into a global…”
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Microleakage in the proximal walls of direct and indirect posterior resin slot restorations by Fruits, Terry J, Knapp, Jason A, Khajotia, Sharukh S

“…This study compared the degree of microleakage in the proximal walls of direct and indirect resin slot restorations in relation to the types of dentin bonding…”
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Use of artificial intelligence to identify cardiovascular compromise in a model of hemorrhagic shock by Glass, Todd F, Knapp, Jason, Amburn, Philip, Clay, Bruce A, Kabrisky, Matt, Rogers, Steven K, Garcia, Victor F

“…OBJECTIVETo determine whether a prototype artificial intelligence system can identify volume of hemorrhage in a porcine model of controlled hemorrhagic shock…”
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