Search Results - "Knackmuss, Stefan H J"

A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells by Reusch, Uwe, Burkhardt, Carmen, Fucek, Ivica, Le Gall, Fabrice, Le Gall, Mikaelle, Hoffmann, Karin, Knackmuss, Stefan HJ, Kiprijanov, Sergej, Little, Melvyn, Zhukovsky, Eugene A

“…To improve recruitment and activation of natural killer (NK) cells to lyse tumor cells, we isolated a human anti-CD16A antibody with similar affinity for the…”
Get full text

Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia by Reusch, Uwe, Harrington, Kimberly H, Gudgeon, Chelsea J, Fucek, Ivica, Ellwanger, Kristina, Weichel, Michael, Knackmuss, Stefan H J, Zhukovsky, Eugene A, Fox, Judith A, Kunkel, Lori A, Guenot, Jeanmarie, Walter, Roland B

“…Randomized studies with gemtuzumab ozogamicin have validated CD33 as a target for antigen-specific immunotherapy of acute myelogenous leukemia (AML). Here, we…”
Get full text

A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19+ tumor cells by Reusch, Uwe, Duell, Johannes, Ellwanger, Kristina, Herbrecht, Carmen, Knackmuss, Stefan HJ, Fucek, Ivica, Eser, Markus, McAleese, Fionnuala, Molkenthin, Vera, Le Gall, Fabrice, Topp, Max, Little, Melvyn, Zhukovsky, Eugene A

“…To harness the potent tumor-killing capacity of T cells for the treatment of CD19 + malignancies, we constructed AFM11, a humanized tetravalent bispecific…”
Get full text