Search Results - "Knüchel, R"

Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro by Noetzel, E, Rose, M, Bornemann, J, Gajewski, M, Knüchel, R, Dahl, E

“…Tumorigenesis and tumor progression are associated with dysfunction of the nuclear transport machinery at the level of import and export receptors…”
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Mesenchymal stem cells can be recruited to wounded tissue via hepatocyte growth factor‐loaded biomaterials by Kamp, J., Paefgen, V., Wöltje, M., Böbel, M., Jaekel, J., Rath, B., Labude, N., Knüchel, R., Jahnen‐Dechent, W., Neuss, Sabine

“…Mesenchymal stem cells (MSC) are precursor cells of mesodermal tissue and, because of their trophic phenotype, they are known to play beneficial roles in wound…”
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Frequent loss of SFRP1 expression in multiple human solid tumours: association with aberrant promoter methylation in renal cell carcinoma by Dahl, E, Wiesmann, F, Woenckhaus, M, Stoehr, R, Wild, P J, Veeck, J, Knüchel, R, Klopocki, E, Sauter, G, Simon, R, Wieland, W F, Walter, B, Denzinger, S, Hartmann, A, Hammerschmied, C G

“…Oncogenic wingless-related mouse mammary tumour virus (Wnt) signalling, caused by epigenetic inactivation of specific pathway regulators like the putative…”
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Growth factor-functionalized silk membranes support wound healing in vitro by Bienert, Michaela, Hoss, M, Bartneck, M, Weinandy, S, Böbel, M, Jockenhövel, S, Knüchel, R, Pottbacker, K, Wöltje, M, Jahnen-Dechent, W, Neuss, S

“…Chronic wounds represent a serious problem in daily medical routine requiring improved wound care. Silk of the domesticated silkworm (Bombyx mori) has been…”
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Different proliferative and survival capacity of CLL-cells in a newly established in vitro model for pseudofollicles by Plander, M, Seegers, S, Ugocsai, P, Diermeier-Daucher, S, Iványi, J, Schmitz, G, Hofstädter, F, Schwarz, S, Orsó, E, Knüchel, R, Brockhoff, G

“…Chronic lymphocytic leukemia (CLL) is a malignancy of mature B-lymphocytes that manifests in a variety of clinical courses. The accumulation of CLL-cells is…”
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Intermediate filament dynamics and breast cancer: Aberrant promoter methylation of the Synemin gene is associated with early tumor relapse by Noetzel, E, Rose, M, Sevinc, E, Hilgers, R-D, Hartmann, A, Naami, A, Knüchel, R, Dahl, E

“…Synemin (SYNM) is a type IV intermediate filament that has recently been shown to interact with the LIM domain protein zyxin, thereby possibly modulating cell…”
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361: The putative tumor suppressor gene Dickkopf-3 (DKK3) and its role in the carcinogenesis of breast cancer by Lorsy, E, Veeck, J, Knüchel, R, Dahl, E

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Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation by Messmann, H, Endlicher, E, Freunek, G, Rümmele, P, Schölmerich, J, Knüchel, R

“…Background and aims: Longstanding ulcerative colitis (UC), especially in the presence of epithelial dysplasia, is associated with an increased risk of…”
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Long-term survival and bipotent terminal differentiation of human mesenchymal stem cells (hMSC) in combination with a commercially available three-dimensional collagen scaffold by Neuss, S, Stainforth, R, Salber, J, Schenck, P, Bovi, M, Knüchel, R, Perez-Bouza, A

“…Researchers working in the field of tissue engineering ideally combine autologous cells and biocompatible scaffolds to replace defect tissues/organs. Due to…”
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Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype by Kristiansen, G, Rose, M, Geisler, C, Fritzsche, F R, Gerhardt, J, Lüke, C, Ladhoff, A-M, Knüchel, R, Dietel, M, Moch, H, Varga, Z, Theurillat, J-P, Gorr, T A, Dahl, E

“…Background: We aimed to clarify the incidence and the clinicopathological value of non-muscle myoglobin (Mb) in a large cohort of non-invasive and invasive…”
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Hypoxia induces the expression of transketolase-like 1 in human colorectal cancer by Bentz, S, Cee, A, Endlicher, E, Wojtal, K A, Naami, A, Pesch, T, Lang, S, Schubert, P, Fried, M, Weber, A, Coy, J F, Goelder, S, Knüchel, R, Hausmann, M, Rogler, G

“…Transketolase-like (TKTL) 1 is one of the key enzymes for anaerobic sugar degradation even in the presence of oxygen (aerobic glycolysis)…”
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Whole bladder photodynamic therapy with 5-aminolevulinic acid using a white light source by Waidelich, R, Beyer, W, Knchel, R, Stepp, H, Baumgartner, R, Schrder, J, Hofstetter, A, Kriegmair, M

“…To determine whether whole bladder photodynamic therapy after intravesical administration of 5-aminolevulinic acid using a white light source would destroy…”
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Sticky Platelet Syndrome: An Underrecognized Cause of Graft Dysfunction and Thromboembolic Complications in Renal Transplant Recipients by Mühlfeld, A. S., Ketteler, M., Schwamborn, K., Eitner, F., Schneider, B., Gladziwa, U., Knüchel, R., Floege, J.

“…Sticky platelet syndrome (SPS) leads to hyperaggregabilty of platelets in response to physiologic stimuli. In this report we describe three patients with…”
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Endoscopic detection of transitional cell carcinoma with 5-aminolevulinic acid: results of 1012 fluorescence endoscopies by Zaak, Dirk, Kriegmair, Martin, Stepp, Herbert, Stepp, Helmut, Baumgartner, Reinhold, Oberneder, Ralph, Schneede, Peter, Corvin, Stefan, Frimberger, Dominic, Knüchel, Ruth, Hofstetter, Alfons

“…Objectives. The initial encouraging results using 5-aminolevulinic acid (5-ALA) induced fluorescence endoscopy (AFE) have promised a procedure with an…”
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Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence by Kriegmair, M, Baumgartner, R, Knüchel, R, Stepp, H, Hofstädter, F, Hofstetter, A

“…We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence. A…”
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Expression of the p53 and maspin protein in primary prostate cancer: Correlation with clinical features by Machtens, Stefan, Serth, Jürgen, Bokemeyer, Carsten, Bathke, Wolfgang, Minssen, Antje, Kollmannsberger, Christian, Hartmann, Jörg, Knüchel, Ruth, Kondo, Masahiko, Jonas, Udo, Kuczyk, Markus

“…The serine protease inhibitor Maspin has been reported to inhibit the invasiveness and motility of prostate cancer tumor cells. Additionally, a p53‐dependent…”
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Barrett's esophagus: a discrepancy between macroscopic and histological diagnosis by Endlicher, E, Rümmele, P, Beer, S, Knüchel, R, Rath, H, Schlottmann, K, Grossmann, J, Woenckhaus, U, Schölmerich, J, Messmann, H

“…The diagnosis of Barrett's esophagus at present requires endoscopic and histological confirmation of specialized intestinal metaplasia. This study…”
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Autofluorescence imaging to optimize 5-ALA-induced fluorescence endoscopy of bladder carcinoma by Frimberger, D, Zaak, D, Stepp, H, Knüchel, R, Baumgartner, R, Schneede, P, Schmeller, N, Hofstetter, A

“…Objectives. To design an optical system for detecting autofluorescence (AF) of bladder tumors and to determine the success of reducing the false-positive rate…”
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Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis by VEECK, J, NIEDERACHER, D, HUSZKA, C, KNÜCHEL, R, DAHL, E, AN, H, KLOPOCKI, E, WIESMANN, F, BETZ, B, GALM, O, CAMARA, O, DÜRST, M, KRISTIANSEN, G

“…The canonical Wnt signalling pathway plays a key role during embryogenesis and defects in this pathway have been implicated in the pathogenesis of various…”
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Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection by Zaak, D, Frimberger, D, Stepp, H, Wagner, S, Baumgartner, R, Schneede, P, Siebels, M, Knüchel, R, Kriegmair, M, Hofstetter, A

“…5-Aminolevulinic acid induced fluorescence endoscopy has outstanding sensitivity for detecting early stage bladder cancer. Nevertheless, a third of the lesions…”
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