Search Results - "Knöbel, Y."

Ferric iron is genotoxic in non-transformed and preneoplastic human colon cells by Knöbel, Y., Weise, A., Glei, M., Sendt, W., Claussen, U., Pool-Zobel, B.L.

“…Iron could be a relevant risk factor for carcinogenesis since it catalyses the formation of reactive oxygen species (ROS), which damage DNA. We previously…”
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Ferric iron increases ROS formation, modulates cell growth and enhances genotoxic damage by 4-hydroxynonenal in human colon tumor cells by Knöbel, Y., Glei, M., Osswald, K., Pool-Zobel, B.L.

“…Iron is a relevant risk factor for colorectal cancer due to its genotoxic properties. Here we hypothesised that iron-overload causes other toxic effects, which…”
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Blood mononucleocytes are sensitive to the DNA damaging effects of iron overload--in vitro and ex vivo results with human and rat cells by Park, Eunju, Glei, Michael, Knöbel, Yvonne, Pool-Zobel, Beatrice L

“…Iron exposure enhances colorectal carcinogeneis, by producing reactive oxygen species, which damage lipids, proteins and DNA. We recently demonstrated that…”
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A Human Volunteer Study to Determine the Prebiotic Effects of Lactulose Powder on Human Colonic Microbiota by Tuohy, Kieran M., Ziemer, Cherie J., Klinder, Annett, Knöbel, Yvonne, Pool-Zobel, Beatrice L., Gibson, Glenn R.

“…The prebiotic effects of lactulose were monitored in a human feeding study. Prebiotics are dietary carbohydrates that have a selective microbial metabolism in…”
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Results of GPS satellite-synchronized end-to-end transient simulation and dynamic state tests on 500 kV and 750 kV circuits by Jodice, J.A., Knobel, Y., Carr, K., Savchenko, E., Molkov, A., Sokolov, V.

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