Search Results - "Klymchenko, A.S."

FLIM nanoscopy resolves the structure and preferential adsorption in the co-nonsolvency of PNIPAM microgels in methanol-water by Centeno, S.P., Nothdurft, K., Klymchenko, A.S., Pich, A., Richtering, W., Wöll, D.

“…Polymer microgels are swollen macromolecular networks with a typical size of hundred of nanometers to several microns that show an extraordinary open and…”
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Monitoring Biophysical Properties of Lipid Membranes by Environment-Sensitive Fluorescent Probes by Demchenko, Alexander P., Mély, Yves, Duportail, Guy, Klymchenko, Andrey S.

“…We review the main trends in the development of fluorescence probes to obtain information about the structure, dynamics, and interactions in biomembranes…”
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Switchable Nile Red-Based Probe for Cholesterol and Lipid Order at the Outer Leaflet of Biomembranes by Kucherak, Oleksandr A, Oncul, Sule, Darwich, Zeinab, Yushchenko, Dmytro A, Arntz, Youri, Didier, Pascal, Mély, Yves, Klymchenko, Andrey S

“…Cholesterol and sphingomyelin form together a highly ordered membrane phase, which is believed to play important biological functions in plasma membranes of…”
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Fluorogenic Squaraine Dimers with Polarity-Sensitive Folding As Bright Far-Red Probes for Background-Free Bioimaging by Karpenko, Iuliia A, Collot, Mayeul, Richert, Ludovic, Valencia, Christel, Villa, Pascal, Mély, Yves, Hibert, Marcel, Bonnet, Dominique, Klymchenko, Andrey S

“…Polarity-sensitive fluorogenic dyes raised considerable attention because they can turn on their fluorescence after binding to biological targets, allowing…”
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Fluorene Analogues of Prodan with Superior Fluorescence Brightness and Solvatochromism by Kucherak, Oleksandr A, Didier, Pascal, Mély, Yves, Klymchenko, Andrey S

“…In a search for environmentally sensitive (solvatochromic) dyes with superior properties, we extended the electronic conjugation of one of the best…”
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Liquid Ordered and Gel Phases of Lipid Bilayers: Fluorescent Probes Reveal Close Fluidity but Different Hydration by M’Baye, Gora, Mély, Yves, Duportail, Guy, Klymchenko, Andrey S.

“…Hydration and fluidity of lipid bilayers in different phase states were studied using fluorescent probes selectively located at the interface. The probe of…”
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Dipolar 3-methoxychromones as bright and highly solvatochromic fluorescent dyes by Kucherak, Oleksandr A, Richert, Ludovic, Mély, Yves, Klymchenko, Andrey S

“…Herein, three environment-sensitive (solvatochromic) fluorescent dyes presenting a strong electron acceptor 3-methoxychromone unit and varied electron donor…”
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Virus-Sized DNA Nanoparticles for Gene Delivery Based on Micelles of Cationic Calixarenes by Rodik, Roman V., Klymchenko, Andrey S., Jain, Namrata, Miroshnichenko, Stanislav I., Richert, Ludovic, Kalchenko, Vitaly I., Mély, Yves

“…Macrocyclic amphiphilic molecules based on calix[4]arenes are highly attractive for controlled supramolecular assembly of DNA into small nanoparticles, since…”
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Counterion-enhanced cyanine dye loading into lipid nano-droplets for single-particle tracking in zebrafish by Kilin, Vasyl N, Anton, Halina, Anton, Nicolas, Steed, Emily, Vermot, Julien, Vandamme, Thierry F, Mely, Yves, Klymchenko, Andrey S

“…Abstract Superior brightness of fluorescent nanoparticles places them far ahead of the classical fluorescent dyes in the field of biological imaging. However,…”
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Biodistribution of X‑Ray Iodinated Contrast Agent in Nano-Emulsions Is Controlled by the Chemical Nature of the Oily Core by Attia, Mohamed F, Anton, Nicolas, Chiper, Manuela, Akasov, Roman, Anton, Halina, Messaddeq, Nadia, Fournel, Sylvie, Klymchenko, Andrey S, Mély, Yves, Vandamme, Thierry F

“…In this study, we investigated the role of the chemical nature of the oil droplet core of nano-emulsions used as contrast agents for X-ray imaging on their…”
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A Universal Nucleoside with Strong Two-Band Switchable Fluorescence and Sensitivity to the Environment for Investigating DNA Interactions by Dziuba, Dmytro, Postupalenko, Viktoriia Y, Spadafora, Marie, Klymchenko, Andrey S, Guérineau, Vincent, Mély, Yves, Benhida, Rachid, Burger, Alain

“…With the aim of developing a new tool to investigate DNA interactions, a nucleoside analogue incorporating a 3-hydroxychromone (3HC) fluorophore as a…”
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Fluorescent Biomembrane Probe for Ratiometric Detection of Apoptosis by Shynkar, Vasyl V, Klymchenko, Andrey S, Kunzelmann, Corinne, Duportail, Guy, Muller, Christian D, Demchenko, Alexander P, Freyssinet, Jean-Marie, Mely, Yves

“…Herein, we developed the first ratiometric fluorescent probe for apoptosis detection. This probe incorporates selectively into the outer leaflet of the cell…”
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Thermodynamically Stable Dispersions of Quantum Dots in a Nematic Liquid Crystal by Prodanov, Maksym F, Pogorelova, Nataliya V, Kryshtal, Alexander P, Klymchenko, Andrey S, Mely, Yves, Semynozhenko, Vladimir P, Krivoshey, Alexander I, Reznikov, Yurii A, Yarmolenko, Sergey N, Goodby, John W, Vashchenko, Valerii V

“…Using transmittance electron microscopy, fluorescence and polarizing optical microscopy, optical spectroscopy, and fluorescent correlation spectroscopy, it was…”
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Fluorescent Amino Acid Undergoing Excited State Intramolecular Proton Transfer for Site-Specific Probing and Imaging of Peptide Interactions by Sholokh, Marianna, Zamotaiev, Oleksandr M, Das, Ranjan, Postupalenko, Viktoriia Y, Richert, Ludovic, Dujardin, Denis, Zaporozhets, Olga A, Pivovarenko, Vasyl G, Klymchenko, Andrey S, Mély, Yves

“…Fluorescent amino acids bearing environment-sensitive fluorophores are highly valuable tools for site-selective probing of peptide/ligand interactions. Herein,…”
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Squaraine as a bright, stable and environment-sensitive far-red label for receptor-specific cellular imaging by Karpenko, I A, Klymchenko, A S, Gioria, S, Kreder, R, Shulov, I, Villa, P, Mély, Y, Hibert, M, Bonnet, D

“…Herein, we show that a far-red arylidene-squaraine dye is stable against nucleophiles, in contrast to arene-squaraines. Owing to the fluorescence enhancement…”
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Location, dynamics and solvent relaxation of a nile red-based phase-sensitive fluorescent membrane probe by Saxena, Roopali, Shrivastava, Sandeep, Haldar, Sourav, Klymchenko, Andrey S., Chattopadhyay, Amitabha

“…•The fluorophore in NR12S is localized at the membrane interface.•NR12S displays phase-sensitive REES in membranes.•Fluorescence properties of NR12S are…”
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A novel leaflet-selective fluorescence labeling technique reveals differences between inner and outer leaflets at high bilayer curvature by Chiantia, Salvatore, Klymchenko, Andrey S., London, Erwin

“…Understanding the differences in the physical properties of the inner and outer leaflet of membranes and how the leaflets are coupled to each other requires…”
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Ab initio study of the solvent H-bonding effect on ESIPT reaction and electronic transitions of 3-hydroxychromone derivatives by Kenfack, Cyril A, Klymchenko, Andrey S, Duportail, Guy, Burger, Alain, Mély, Yves

“…The electronic transitions occurring in 4-(N,N-dimethylamino)-3-hydroxyflavone (DMAF) and 2-furanyl-3-hydroxychromone (FHC) were investigated using the TDDFT…”
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Rational Design of a Solvatochromic Fluorescent Uracil Analogue with a Dual-Band Ratiometric Response Based on 3-Hydroxychromone by Dziuba, Dmytro, Karpenko, Iuliia A., Barthes, Nicolas P. F., Michel, Benoît Y., Klymchenko, Andrey S., Benhida, Rachid, Demchenko, Alexander P., Mély, Yves, Burger, Alain

“…Fluorescent nucleoside analogues with strong and informative responses to their local environment are in urgent need for DNA research. In this work, the…”
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Calixarenes and related macrocycles as gene delivery vehicles by Rodik, Roman V., Klymchenko, Andrey S., Mely, Yves, Kalchenko, Vitaly I.

“…The success of gene therapy depends largely on the development of new efficient gene delivery vehicles. The emerging class of molecules for this application is…”
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