Search Results - "Klukovich, Rachel"
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ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells
Published in Proceedings of the National Academy of Sciences - PNAS (09-01-2018)“…N6-methyladenosine (m6A) represents one of the most common RNA modifications in eukaryotes. Specific m6A writer, eraser, and reader proteins have been…”
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Journal Article -
2
Motile cilia of the male reproductive system require miR-34/miR-449 for development and function to generate luminal turbulence
Published in Proceedings of the National Academy of Sciences - PNAS (26-02-2019)“…Cilia are cell-surface, microtubule-based organelles that project into extracellular space. Motile cilia are conserved throughout eukaryotes, and their beat…”
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3
Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease
Published in Epigenetics & chromatin (27-02-2018)“…Environmental toxicants such as DDT have been shown to induce the epigenetic transgenerational inheritance of disease (e.g., obesity) through the germline. The…”
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Journal Article -
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Environmental Toxicant Induced Epigenetic Transgenerational Inheritance of Prostate Pathology and Stromal-Epithelial Cell Epigenome and Transcriptome Alterations: Ancestral Origins of Prostate Disease
Published in Scientific reports (18-02-2019)“…Prostate diseases include prostate cancer, which is the second most common male neoplasia, and benign prostatic hyperplasia (BPH), which affects approximately…”
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Journal Article -
5
m6A-dependent biogenesis of circular RNAs in male germ cells
Published in Cell research (01-03-2020)“…The majority of circular RNAs (circRNAs) spliced from coding genes contain open reading frames (ORFs) and thus, have protein coding potential. However, it…”
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Journal Article -
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Environmental toxicant induced epigenetic transgenerational inheritance of ovarian pathology and granulosa cell epigenome and transcriptome alterations: ancestral origins of polycystic ovarian syndrome and primary ovarian insufficiency
Published in Epigenetics (03-08-2018)“…Two of the most prevalent ovarian diseases affecting women's fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome…”
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Environmental toxicant induced epigenetic transgenerational inheritance of ovarian pathology and granulosa cell epigenome and transcriptome alterations: ancestral origins of polycystic ovarian syndrome and primary ovarian insufiency
Published in Epigenetics (01-01-2018)“…Two of the most prevalent ovarian diseases affecting women's fertility and health are Primary Ovarian Insufficiency (POI) and Polycystic Ovarian Syndrome…”
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Journal Article -
8
Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of disease
Published in Environmental epigenetics (01-04-2018)“…Epigenetic transgenerational inheritance of disease and phenotypic variation can be induced by several toxicants, such as vinclozolin. This phenomenon can…”
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9
Functions of Saccharomyces cerevisiae Ecm27p, a putative Na(+)/Ca(2+) exchanger, in calcium homeostasis, carbohydrate storage and cell cycle reentry from the quiescent phase
Published in Microbiological research (01-05-2016)“…The quiescent phase of the cell cycle is of fundamental importance for fungi, yet our understanding of this phase of the cycle is much less well understood…”
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Journal Article -
10
Functions of Saccharomyces cerevisiae Ecm27p, a putative Na+/Ca2+ exchanger, in calcium homeostasis, carbohydrate storage and cell cycle reentry from the quiescent phase
Published in Microbiological research (01-05-2016)“…The quiescent phase of the cell cycle is of fundamental importance for fungi, yet our understanding of this phase of the cycle is much less well understood…”
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Journal Article -
11
Epigenetic transgenerational inheritance of testis pathology and Sertoli cell epimutations: generational origins of male infertility
Published in Environmental epigenetics (01-07-2019)“…Abstract Male reproductive health has been in decline for decades with dropping sperm counts and increasing infertility, which has created a significant…”
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Journal Article -
12
Ethanol induces calcium influx via the Cch1-Mid1 transporter in Saccharomyces cerevisiae
Published in Archives of microbiology (01-05-2011)“…Yeast suffers from a variety of environmental stresses, such as osmotic pressure and ethanol produced during fermentation. Since calcium ions are protective…”
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13
Epigenetic Regulation of Spermatogenesis and Transgenerational Epigenetic Inheritance
Published 2018“…Epigenetics is defined as genomic modifications that alter gene expression without changing the nucleic acid sequence. These modifications come in hundreds of…”
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Dissertation -
14
Ethanol induces calcium influx via the Cchl-Midl transporter in Saccharomyces cerevisiae
Published in Archives of microbiology (2011)Get full text
Journal Article -
15
m 6 A-dependent biogenesis of circular RNAs in male germ cells
Published in Cell research (01-03-2020)“…The majority of circular RNAs (circRNAs) spliced from coding genes contain open reading frames (ORFs) and thus, have protein coding potential. However, it…”
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Journal Article -
16
Ethanol induces calcium influx via the Cch1-Mid1 transporter in Saccharomycescerevisiae
Published in Archives of microbiology (01-04-2011)“…Yeast suffers from a variety of environmental stresses, such as osmotic pressure and ethanol produced during fermentation. Since calcium ions are protective…”
Get full text
Journal Article