Search Results - "Kluiver, Thomas A"

Hepatocyte organoids and cell transplantation: What the future holds by Peng, Weng Chuan, Kraaier, Lianne J., Kluiver, Thomas A.

“…Historically, primary hepatocytes have been difficult to expand or maintain in vitro. In this review, we will focus on recent advances in establishing…”
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Extracellular vesicle‐mediated delivery of CRISPR/Cas9 ribonucleoprotein complex targeting proprotein convertase subtilisin‐kexin type 9 (Pcsk9) in primary mouse hepatocytes by Ilahibaks, Nazma F., Kluiver, Thomas A., Jong, Olivier G., Jager, Saskia C. A., Schiffelers, Raymond M., Vader, Pieter, Peng, Weng Chuan, Lei, Zhiyong, Sluijter, Joost P. G.

“…The loss‐of‐function of the proprotein convertase subtilisin–kexin type 9 (Pcsk9) gene has been associated with significant reductions in plasma serum…”
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Targeting pediatric cancers via T-cell recognition of the monomorphic MHC class I-related protein MR1 by Cornel, Annelisa M., van der Sman, Loutje, van Dinter, Jip T, Arrabito, Marta, Dunnebach, Ester, van Hoesel, Marliek, Kluiver, Thomas A, Lopes, Ana P, Dautzenberg, Noël M M, Dekker, Linde, van Rijn, Jorik M, van den Beemt, Denise A M H, Buhl, Juliane L, du Chatinier, Aimee, Barneh, Farnaz, Lu, Yuyan, Lo Nigro, Luca, Krippner-Heidenreich, Anja, Sebestyén, Zsolt, Kuball, Jurgen, Hulleman, Esther, Drost, Jarno, van Heesch, Sebastiaan, Heidenreich, Olaf T, Peng, Weng Chuan, Nierkens, Stefan

“…Human leukocyte antigen (HLA) restriction of conventional T-cell targeting introduces complexity in generating T-cell therapy strategies for patients with…”
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Dual targeting of cancer metabolome and stress antigens affects transcriptomic heterogeneity and efficacy of engineered T cells by Hernández-López, Patricia, van Diest, Eline, Brazda, Peter, Heijhuurs, Sabine, Meringa, Angelo, Hoorens van Heyningen, Lauren, Riillo, Caterina, Schwenzel, Caroline, Zintchenko, Marina, Johanna, Inez, Nicolasen, Mara J. T., Cleven, Astrid, Kluiver, Thomas A., Millen, Rosemary, Zheng, Jiali, Karaiskaki, Froso, Straetemans, Trudy, Clevers, Hans, de Bree, Remco, Stunnenberg, Hendrik G., Peng, Weng Chuan, Roodhart, Jeanine, Minguet, Susana, Sebestyén, Zsolt, Beringer, Dennis X., Kuball, Jürgen

“…Few cancers can be targeted efficiently by engineered T cell strategies. Here, we show that γδ T cell antigen receptor (γδ TCR)-mediated cancer metabolome…”
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