Search Results - "Klugman, K P"

Use of a Rapid Test of Pneumococcal Colonization Density to Diagnose Pneumococcal Pneumonia by Albrich, W. C., Madhi, S. A., Adrian, P. V., van Niekerk, N., Mareletsi, T., Cutland, C., Wong, M., Khoosal, M., Karstaedt, A., Zhao, P., Deatly, A., Sidhu, M., Jansen, K. U., Klugman, K. P.

“…Background. There is major need for a more sensitive assay for the diagnosis of pneumococcal community-acquired pneumonia (CAP). We hypothesized that…”
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Nomenclature of Major Antimicrobial-Resistant Clones of Streptococcus pneumoniae Defined by the Pneumococcal Molecular Epidemiology Network by MCGEE, L, MCDOUGAL, L, KLUGMAN, K. P, ZHOU, J, SPRATT, B. G, TENOVER, F. C, GEORGE, R, HAKENBRFCK, R, HRYNIEWICZ, W, LEFEVRE, J. C, TOMASZ, A

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Mutations within the rplD Gene of Linezolid-Nonsusceptible Streptococcus pneumoniae Strains Isolated in the United States by DONG, W, CHOCHUA, S, MCGEE, L, JACKSON, D, KLUGMAN, K. P, VIDAL, J. E

“…Three invasive Streptococcus pneumoniae strains nonsusceptible to linezolid were isolated in the United States between 2001 and 2012 from the CDC's Active…”
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Estimating the prevalence of coinfection with influenza virus and the atypical bacteria Bordetella pertussis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae by Mina, M. J., Burke, R. M., Klugman, K. P.

“…Coinfections with common bacterial respiratory pathogens and influenza viruses are well-known causes of disease, often via synergistic interactions between the…”
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Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose by Klugman, K.P, Madhi, S.A, Adegbola, R.A, Cutts, F, Greenwood, B, Hausdorff, W.P

“…Abstract Protection against serotype 1 could not be demonstrated in two randomized trials of 9 valent pneumococcal conjugate vaccines. An analysis of the…”
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Increased Disease Burden and Antibiotic Resistance of Bacteria Causing Severe Community-Acquired Lower Respiratory Tract Infections in Human Immunodeficiency Virus Type 1-Infected Children by Madhi, Shabir A, Petersen, Karen, Madhi, Anas, Khoosal, Mannikhant, Klugman, Keith P.

“…To improve the management of lower respiratory tract infections (LRTI) in human immunodeficiency virus type 1 (HIV-1)-infected children, we assessed the burden…”
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Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro by Anderson, R., Steel, H. C., Cockeran, R., von Gottberg, A., de Gouveia, L., Klugman, K. P., Mitchell, T. J., Feldman, C.

“…Objectives To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin,…”
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Temporal association of infant immunisation with pneumococcal conjugate vaccine on the ecology of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonisation in a rural South African community by Nzenze, S.A, Shiri, T, Nunes, M.C, Klugman, K.P, Kahn, K, Twine, R, de Gouveia, L, von Gottberg, A, Madhi, S.A

“…Highlights • PCV immunisation at 6, 10 and 40 weeks, with no catch-up campaign, reduces vaccine serotype colonisation in infants. • Also, community-wide…”
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Severity of illness scoring systems in patients with bacteraemic pneumococcal pneumonia: implications for the intensive care unit care by Feldman, C., Alanee, S., Yu, V.L., Richards, G.A., Ortqvist, A., Rello, J., Chiou, C.C. C., Chedid, M.B. F., Wagener, M.M., Klugman, K.P.

“…Severity of illness scoring systems are useful for decisions on the management of patients with community-acquired pneumonia (CAP), including assessing the…”
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An International Prospective Study of Pneumococcal Bacteremia: Correlation with In Vitro Resistance, Antibiotics Administered, and Clinical Outcome by Yu, Victor L., Chiou, Christine C. C., Feldman, Charles, Ortqvist, Ake, Rello, Jordi, Morris, Arthur J., Baddour, Larry M., Luna, Carlos M., Snydman, David R., Ip, Margaret, Ko, Wen Chien, Chedid, M. Bernadete F., Andremont, Antoine, Klugman, Keith P.

“…We performed a prospective, international, observational study of 844 hospitalized patients with blood cultures positive for Streptococcus pneumoniae. Fifteen…”
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Association of Serotypes of Streptococcus pneumoniae with Disease Severity and Outcome in Adults: An International Study by Alanee, S. R. J., McGee, L., Jackson, D., Chiou, C. C., Feldman, C., Morris, A. J., Ortqvist, A., Rello, J., Luna, C. M., Baddour, L. M., Ip, M., Yu, V. L., Klugman, K. P.

“…Background. The introduction of conjugate pneumococcal vaccination for children has reduced the burden of invasive disease due to pneumococcal conjugate…”
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Outcome of Cephalosporin Treatment for Serious Infections Due to Apparently Susceptible Organisms Producing Extended-Spectrum β-Lactamases: Implications for the Clinical Microbiology Laboratory by PATERSON, David L, KO, Wen-Chien, VON GOTTBERG, Anne, CASELLAS, Jose Maria, MULAZIMOGLU, Lutfiye, KLUGMAN, Keith P, BONOMO, Robert A, RICE, Louis B, MCCORMACK, Joseph G, YU, Victor L

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Immunogenicity and Impact on Nasopharyngeal Carriage of a Nonavalent Pneumococcal Conjugate Vaccine by Mbelle, Nontombi, Huebner, Robin E., Wasas, Avril D., Kimura, Alan, Chang, Ih, Klugman, Keith P.

“…The safety, immunogenicity, and impact on carriage of a nonvalent pneumococcal vaccine given at ages 6, 10, and 14 weeks were examined in a double-blind,…”
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A century of pneumococcal vaccination research in humans by Grabenstein, J.D., Klugman, K.P.

“…Sir Almroth Wright coordinated the first trial of a whole-cell pneumococcal vaccine in South Africa from 1911 to 1912. Wright started a chain of events that…”
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Fluoroquinolone Resistance in Invasive Streptococcus pyogenes Isolates Due to Spontaneous Mutation and Horizontal Gene Transfer by PLETZ, M. W. R, MCGEE, L, VAN BENEDEN, C. A, PETIT, S, BARDSLEY, M, BARLOW, M, KLUGMAN, K. P

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Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae by Anderson, R., Steel, H. C., Cockeran, R., Smith, A. M., von Gottberg, A., de Gouveia, L., Brink, A., Klugman, K. P., Mitchell, T. J., Feldman, C.

“…Objectives To investigate the effects of clarithromycin (0.01–0.5 mg/L) alone or in combination with ceftriaxone (0.1 and 0.25 mg/L) on pneumolysin production…”
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The successful clone: the vector of dissemination of resistance in Streptococcus pneumoniae by KLUGMAN, Keith P

“…A small number of pneumococcal clones dominate the population of antibiotic-resistant pneumococci. The emergence of fluoroquinolone resistance in these clones…”
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Impact of conjugate Haemophilus influenzae type b (Hib) vaccine introduction in South Africa by VON GOTTBERG, A, DE GOUVEIA, L, MADHI, S. A, DU PLESSIS, M, QUAN, V, SOMA, K, HUEBNER, R, FLANNERY, B, SCHUCHAT, A, KLUGMAN, K. P

“…To analyse trends in reported invasive Haemophilus influenzae disease in South Africa within the first five years of introduction of conjugate Haemophilus…”
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Epidemiology of Ciprofloxacin Resistance and Its Relationship to Extended-Spectrum β-Lactamase Production in Klebsiella pneumoniae Isolates Causing Bacteremia by Paterson, David L., Mulazimoglu, Lutfiye, Casellas, Jose Maria, Ko, Wen-Chien, Goossens, Herman, Von Gottberg, Anne, Mohapatra, Sunita, Trenholme, Gordon M., Klugman, Keith P., McCormack, Joseph G., Yu, Victor L.

“…A prospective study of Klebsiella pneumoniae bacteremia was performed in 12 hospitals in 7 countries. Of 452 episodes of bacteremia, 25 (5.5%) were caused by…”
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Bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in cerebrospinal fluid of children with acute bacterial meningitis by KLUGMAN, K. P, FRIEDLAND, I. R, BRADLEY, J. S

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