Search Results - "Klotz, L"

Posttranscriptional regulation of FOXO expression: microRNAs and beyond by Urbánek, P, Klotz, L‐O

“…Forkhead box, class O (FOXO) transcription factors are major regulators of diverse cellular processes, including fuel metabolism, oxidative stress response and…”
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Activities and Effects of Ergot Alkaloids on Livestock Physiology and Production by Klotz, James L

“…Consumption of feedstuffs contaminated with ergot alkaloids has a broad impact on many different physiological mechanisms that alters the homeostasis of…”
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Global Impact of Ergot Alkaloids by Klotz, James L

“…For many years, ergot alkaloids have been considered both a problem to be mitigated and a potential medical cure [...]…”
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Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress by Manolopoulos, K N, Klotz, L-O, Korsten, P, Bornstein, S R, Barthel, A

“…Oxidative stress is an important determinant not only in the pathogenesis of Alzheimer's disease (AD), but also in insulin resistance (InsRes) and diabetic…”
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The endocannabinoid system in bovine tissues: characterization of transcript abundance in the growing Holstein steer by Kent-Dennis, Coral, Klotz, James L

“…The endocannabinoid system (ECS) is highly integrated with seemingly all physiological and pathophysiological processes in the body. There is increasing…”
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Denosumab for the prevention of skeletal complications in metastatic castration-resistant prostate cancer: comparison of skeletal-related events and symptomatic skeletal events by Smith, M.R., Coleman, R.E., Klotz, L., Pittman, K., Milecki, P., Ng, S., Chi, K.N., Balakumaran, A., Wei, R., Wang, H., Braun, A., Fizazi, K.

“…In this analysis of a phase III trial in patients with castration-resistant prostate cancer and bone metastases, treatment with denosumab reduced the risk of…”
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Active surveillance for intermediate-risk prostate cancer by Dall'Era, M A, Klotz, L

“…Background: Utilization of active surveillance (AS) for prostate cancer is increasing. Optimal selection criteria for this approach are undefined and questions…”
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Prognostic relevance of regional lymph-node distribution in patients with N1-positive non-small cell lung cancer: A retrospective single-center analysis by Eichhorn, F., Klotz, L.V., Muley, T., Kobinger, S., Winter, H., Eichhorn, M.E.

“…•Nodal positive (N1) NSCLC population can be split towards different prognostic subgroups.•Increased nodal burden (pN1b, multiple zone involvement) is…”
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Isoflavone supplementation, via red clover hay, alters the rumen microbial community and promotes weight gain of steers grazing mixed grass pastures by Harlow, Brittany E, Flythe, Michael D, Kagan, Isabelle A, Goodman, Jack P, Klotz, James L, Aiken, Glen E

“…Biochanin A, an isoflavone present in the pasture legume red clover (Trifloium pratense L.), alters fermentation in the rumen of cattle and other ruminants…”
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Metformin and prostate cancer stem cells: a novel therapeutic target by Mayer, M J, Klotz, L H, Venkateswaran, V

“…Prostate cancer is the second most frequently diagnosed cancer in the world. Localized disease can be effectively treated with radiation therapy or radical…”
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Immunomodulation by cannabidiol in bovine primary ruminal epithelial cells by Kent-Dennis, C, Klotz, James L

“…Abstract Background Ruminant livestock experience a number of challenges, including high concentrate diets, weaning and transport, which can increase their…”
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Influence of postruminal casein infusion and exogenous glucagon-like peptide 2 administration on the jejunal mucosal transcriptome in cattle by Trotta, Ronald J, Swanson, Kendall C, Klotz, James L, Harmon, David L

“…We previously demonstrated that postruminal casein infusion and exogenous glucagon-like peptide 2 (GLP-2) administration independently stimulated growth and…”
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Effect of biochanin A on the rumen microbial community of Holstein steers consuming a high fiber diet and subjected to a subacute acidosis challenge by Harlow, Brittany E, Flythe, Michael D, Klotz, James L, Harmon, David L, Aiken, Glen E

“…Subacute rumen acidosis (SARA) occurs when highly fermentable carbohydrates are introduced into the diet, decreasing pH and disturbing the microbial ecology of…”
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High socioeconomic impact on prescription behavior despite unrestricted access to disease-modifying therapies in people with multiple sclerosis by Samadzadeh, S, Havla, J, Lepka, K, Brinks, R, Meuth, S G, Klotz, L, Albrecht, P

“…Economic and health care restraints strongly impact on drug prescription for chronic diseases. We aimed to identify potential factors for prescription behavior…”
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Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer by NAM, R. K, SUGAR, L, TRACHTENBERG, J, NAROD, S. A, SETH, A, YANG, W, SRIVASTAVA, S, KLOTZ, L. H, YANG, L-Y, STANIMIROVIC, A, ENCIOIU, E, NEILL, M, LOBLAW, D. A

“…The prostate-specific gene, TMPRSS2 is fused with the gene for the transcription factor ERG in a large proportion of human prostate cancers. The prognostic…”
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Active surveillance for prostate cancer: patient selection and management by Klotz, L

“…Screening for prostate cancer using prostate-specific antigen (PSA) has been appealing. However, the significant associated decline in prostate cancer…”
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Serotonin receptor‐mediated vasorelaxation occurs primarily through 5‐HT4 activation in bovine lateral saphenous vein by Trotta, Ronald J., Harmon, David L., Klotz, James L.

“…To better understand mechanisms of serotonin‐ (5‐HT) mediated vasorelaxation, isolated lateral saphenous veins from cattle were assessed for vasoactivity using…”
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Patient selection for prostate focal therapy in the era of active surveillance: an International Delphi Consensus Project by Tay, K J, Scheltema, M J, Ahmed, H U, Barret, E, Coleman, J A, Dominguez-Escrig, J, Ghai, S, Huang, J, Jones, J S, Klotz, L H, Robertson, C N, Sanchez-Salas, R, Scionti, S, Sivaraman, A, de la Rosette, J, Polascik, T J

“…Background: Whole-gland extirpation or irradiation is considered the gold standard for curative oncological treatment for localized prostate cancer, but is…”
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Active Surveillance with Selective Delayed Intervention Using PSA Doubling Time for Good Risk Prostate Cancer by Klotz, Laurence

“…Good risk prostate cancer, defined as patients with a Gleason score of 6 or less, PSA <10–15, and T1c–T2a, now constitutes 50% of newly diagnosed prostate…”
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Influence of Prolonged Serotonin and Ergovaline Pre-Exposure on Vasoconstriction Ex Vivo by Valente, Eriton E L, Harmon, David L, Klotz, James L

“…Ergot alkaloid mycotoxins interfere in many functions associated with serotonergic neurotransmitters. Therefore, the objective was to evaluate whether the…”
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