Search Results - "Klotz, K"

International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors by Fredholm, B B, IJzerman, A P, Jacobson, K A, Klotz, K N, Linden, J

“…Four adenosine receptors have been cloned and characterized from several mammalian species. The receptors are named adenosine A 1 , A 2A , A 2B , and A 3 . The…”
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Novel 8-(p-substituted-phenyl/benzyl)xanthines with selectivity for the A2A adenosine receptor possess bronchospasmolytic activity by Yadav, Rakesh, Bansal, Ranju, Kachler, Sonja, Klotz, K.N.

“…A new series of 8-(p-substituted-phenyl/benzyl)xanthines has been synthesized and evaluated in vitro for adenosine receptor binding affinity and in vivo for…”
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Adenosine receptors and their ligands by Klotz, K N

“…The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled receptors distinguished as A1, A2A, A2B and A3 receptors. Their…”
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Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells by Hoffmann, C, Leitz, M R, Oberdorf-Maass, S, Lohse, M J, Klotz, K-N

“…Although many beta1-receptor antagonists and beta2-receptor agonists have been used in pharmacotherapy for many years their pharmacological properties at all…”
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SpermCheck® Fertility, an immunodiagnostic home test that detects normozoospermia and severe oligozoospermia by Coppola, M.A., Klotz, K.L., Kim, K.-a., Cho, H.Y., Kang, J., Shetty, J., Howards, S.S., Flickinger, C.J., Herr, J.C.

“…BACKGROUND A simple and inexpensive home sperm test could be of considerable value to couples attempting to conceive and to men curious about their fertility…”
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Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells by Klotz, K N, Hessling, J, Hegler, J, Owman, C, Kull, B, Fredholm, B B, Lohse, M J

“…Four adenosine receptor subtypes of the family of G protein-coupled receptors, designated A1, A2A, A2B and A3 are currently known. In this study all human…”
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Adenosine receptors and cancer by Fishman, P, Bar-Yehuda, S, Synowitz, M, Powell, J D, Klotz, K N, Gessi, S, Borea, P A

“…The A(1), A(2A), A(2B) and A(3) G-protein-coupled cell surface adenosine receptors (ARs) are found to be upregulated in various tumor cells. Activation of the…”
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A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists by Venkatesan, G, Paira, P, Cheong, S L, Federico, S, Klotz, K N, Spalluto, G, Pastorin, G

“…An efficient synthetic procedure was adopted to synthesize a series of new molecules containing the pyrazolo[3,4-d]pyrimidine (PP) scaffold, which have been…”
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Influence of body water distribution on skin thickness: measurements using high-frequency ultrasound by Eisenbeiss, C., Welzel, J., Eichler, W., Klotz, K.

“…Background Although it is known that the skin acts as a water reservoir and participates in the fluid content of the whole body, no method has been established…”
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Effects of candesartan and enalaprilat on the organ-specific microvascular permeability during haemorrhagic shock in rats by Schumacher, J, Puchakayala, M.R., Binkowski, K, Eichler, W, Dendorfer, A, Klotz, K.-F.

“…To counteract the contribution of angiotensin II to shock-induced ischaemic organ damage pharmacologic blockade of the renin–angiotensin-system (RAS) is…”
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Leydig-cell-tumor of the ovary that responded to GnRH-analogue administration - case report and review of the literature by Klotz, R K, Müller-Holzner, E, Fessler, S, Reimer, D U, Zervomanolakis, I, Seeber, B, Mattle, V, Wildt, L

“…Progressive hirsutism can be a symptom of an androgen-producing tumor, especially in postmenopausal women. We report a case of a 58-year-old woman who…”
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Introduction of alkynyl chains on C-8 of adenosine led to very selective antagonists of the A3 adenosine receptor by VOLPINI, Rosaria, COSTANZI, Stefano, LAMBERTUCCI, Catia, VITTORI, Sauro, KLOTZ, K.-N, LORENZEN, Anna, CRISTALLI, Gloria

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Equatorial Segment Protein (ESP) Is a Human Alloantigen Involved in Sperm-Egg Binding and Fusion by Wolkowicz, M. J, Digilio, L, Klotz, K, Shetty, J, Flickinger, C. J, Herr, J. C

“…The equatorial segment of the sperm head is known to play a role in fertilization; however, the specific sperm molecules contributing to the integrity of the…”
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Characterizing sugarbeet varieties for postharvest storage losses is complicated by environmental effects and genotype x environment interactions by Campbell, L.G, Klotz, K.L

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Hominoid-specific SPANXA/D genes demonstrate differential expression in individuals and protein localization to a distinct nuclear envelope domain during spermatid morphogenesis by Westbrook, V.A., Schoppee, P.D., Vanage, G.R., Klotz, K.L., Diekman, A.B., Flickinger, C.J., Coppola, M.A., Herr, J.C.

“…Human sperm protein associated with the nucleus on the X chromosome consists of a five-member gene family (SPANXA1, SPANXA2, SPANXB, SPANXC and SPANXD)…”
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Signaling by extracellular nucleotides and nucleosides by Illes, P, Klotz, K N, Lohse, M J

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The effect of moderate hypovolaemia on microcirculation in healthy older blood donors by Janetzko, K., Klüter, H., Kirchner, H., Klotz, K.‐F.

“…Compensation for acute blood loss requires cardiovascular integrity. In older people, asymptomatic cardiovascular impairment is common. In these subjects, even…”
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"Your Sound Is Like Your Sweat": Miles Davis's Disembodied Sound Discourse by Klotz, Kelsey A. K.

“…With an image tarnished in the jazz press through association with the drug, a sound that had been described by Barry Ulanov as feeble, and a career that…”
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[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors by Varani, K, Merighi, S, Gessi, S, Klotz, K N, Leung, E, Baraldi, P G, Cacciari, B, Romagnoli, R, Spalluto, G, Borea, P A

“…The lack of a radiolabeled selective A(3) adenosine receptor antagonist is a major drawback for an adequate characterization of this receptor subtype. This…”
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Spermatid-Specific Expression of the Novel X-Linked Gene Product SPAN-X Localized to the Nucleus of Human Spermatozoa by WESTBROOK, V. A, DIEKMAN, A. B, FLICKINGER, C. J, HERR, J. C, KLOTZ, K. L, KHOLE, V. V, VON KAP-HERR, C, GOLDEN, W. L, EDDY, R. L, SHOWS, T. B, STOLER, M. H, LEE, C.-Y. G

“…Formation of mature spermatozoa involves a series of dramatic molecular and morphological changes in the male germ cell lineage. These changes result from the…”
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